G3P1_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: G3P1_DROME
• UniProt AC: P07486
• Protein Name: Glyceraldehyde-3-phosphate dehydrogenase 1
• Gene Name: Gapdh1
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 332
• Subcellular Localization: Cytoplasm.
• Protein Sequence: MSKIGINGFGRIGRLVLRAAIDKGASVVAVNDPFIDVNYMVYLFKFDSTHGRFKGTVAAEGGFLVVNGQKITVFSERDPANINWASAGAEYVVESTGVFTTIDKASTHLKGGAKKVIISAPSADAPMFVCGVNLDAYSPDMKVVSNASCTTNCLAPLAKVINDNFEIVEGLMTTVHATTATQKTVDGPSGKLWRDGRGAAQNIIPAATGAAKAVGKVIPALNGKLTGMAFRVPTPNVSVVDLTVRLGKGATYDEIKAKVEEASKGPLKGILGYTDEEVVSTDFFSDTHSSVFDAKAGISLNDKFVKLISWYDNEFGYSNRVIDLIKYMQSKD

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
3	Acetylation	-----MSKIGINGFG -----CCCCCCCCCC	43.59	21791702
70	Ubiquitination	FLVVNGQKITVFSER EEEECCEEEEEEECC	41.57	31113955
148	Phosphorylation	MKVVSNASCTTNCLA CEEECCCCCCCCCHH	19.08	21082442
150	Phosphorylation	VVSNASCTTNCLAPL EECCCCCCCCCHHHH	20.67	21082442
173	Phosphorylation	EIVEGLMTTVHATTA HHHHHHHHEEEEEEC	30.61	21082442
174	Phosphorylation	IVEGLMTTVHATTAT HHHHHHHEEEEEECC	9.06	21082442
178	Phosphorylation	LMTTVHATTATQKTV HHHEEEEEECCCCCC	11.33	21082442
181	Phosphorylation	TVHATTATQKTVDGP EEEEEECCCCCCCCC	28.62	21082442
191	Acetylation	TVDGPSGKLWRDGRG CCCCCCCCCCCCCCC	49.57	21791702
208	Phosphorylation	QNIIPAATGAAKAVG HHHHHHHHHHHHHHH	29.47	22817900
238	Phosphorylation	RVPTPNVSVVDLTVR ECCCCCEEEEEEEEE	24.06	22817900
273	Phosphorylation	PLKGILGYTDEEVVS CCCEECCCCCCCCEE	13.94	17372656
274	Phosphorylation	LKGILGYTDEEVVST CCEECCCCCCCCEEC	34.83	17372656

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of G3P1_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of G3P1_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of G3P1_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
HSP7B_DROME	Hsc70-2	physical	22036573
TBB2_DROME	betaTub85D	physical	22036573
G3P2_DROME	Gapdh2	physical	22036573
RS15B_DROME	RpS15Ab	physical	22036573
SRF_DROME	bs	physical	22036573
GPDA_DROME	Gpdh	physical	12756285

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.