F86B2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: F86B2_HUMAN
• UniProt AC: P0C5J1
• Protein Name: Putative protein N-methyltransferase FAM86B2 {ECO:0000305}
• Gene Name: FAM86B2
• Organism: Homo sapiens (Human).
• Sequence Length: 330
• Protein Sequence: MAPEENAGTELLLQGFERRFLAVRTLRSFPWQSLEAKLRDSSDSELLRDILQKTVRHPVCVKHPPSVKYAWCFLSELIKKHEAVHTEPLDKLYEVLAETLMAKESTQGHRSYLLSSGGSVTLSKSTAIISHGTTGLVTWDAALYLAEWAIENPAAFINRTVLELGSGAGLTGLAICKMCRPRAYIFSDPHSRILEQLRGNVLLNGLSLEADITGNLDSPRVTVAQLDWDVAMVHQLSAFQPDVVIAADVLYCPEAIVSLVGVLQRLAACREHKRAPEVYVAFTVRNPETCQLFTTELGRDGIRWEAEAHHDQKLFPYGEHLEMAMLNLTL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MAPEENAG -------CCCCCCHH	14.67	-
33	Phosphorylation	LRSFPWQSLEAKLRD HHCCCHHHHHHHHCC	25.06	24719451
37	Ubiquitination	PWQSLEAKLRDSSDS CHHHHHHHHCCCCCH	34.38	22817900
62	Ubiquitination	VRHPVCVKHPPSVKY CCCCCHHCCCCCHHH	45.31	-
105	Phosphorylation	ETLMAKESTQGHRSY HHHHHHHCCCCCCCE	25.89	-
106	Phosphorylation	TLMAKESTQGHRSYL HHHHHHCCCCCCCEE	39.39	-
111	Phosphorylation	ESTQGHRSYLLSSGG HCCCCCCCEEECCCC	17.92	24400094
116	Phosphorylation	HRSYLLSSGGSVTLS CCCEEECCCCEEEEC	47.33	24400094
119	Phosphorylation	YLLSSGGSVTLSKST EEECCCCEEEECCCE	18.56	24400094
121	Phosphorylation	LSSGGSVTLSKSTAI ECCCCEEEECCCEEE	27.32	-
123	Phosphorylation	SGGSVTLSKSTAIIS CCCEEEECCCEEEEE	18.39	-
177	Ubiquitination	LTGLAICKMCRPRAY HHHHHHHHHCCCCEE	34.62	-
187	Phosphorylation	RPRAYIFSDPHSRIL CCCEEEECCCCHHHH	40.45	27251275

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of F86B2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of F86B2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of F86B2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TCPB_HUMAN	CCT2	physical	23349634
TCPG_HUMAN	CCT3	physical	23349634
TCPD_HUMAN	CCT4	physical	23349634
TCPE_HUMAN	CCT5	physical	23349634
TCPZ_HUMAN	CCT6A	physical	23349634
TCPW_HUMAN	CCT6B	physical	23349634
TCPH_HUMAN	CCT7	physical	23349634
TCPQ_HUMAN	CCT8	physical	23349634
TCPA_HUMAN	TCP1	physical	23349634
TBB2A_HUMAN	TUBB2A	physical	23349634
TBB3_HUMAN	TUBB3	physical	23349634
TBB4A_HUMAN	TUBB4A	physical	23349634
TBB6_HUMAN	TUBB6	physical	23349634
UBB_HUMAN	UBB	physical	23349634
UBC_HUMAN	UBC	physical	23349634

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.