ESPB1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ESPB1_HUMAN
• UniProt AC: Q96BH3
• Protein Name: Epididymal sperm-binding protein 1
• Gene Name: ELSPBP1
• Organism: Homo sapiens (Human).
• Sequence Length: 223
• Subcellular Localization: Secreted .
• Protein Description: Binds to spermatozoa upon ejaculation and may play a role in sperm capacitation. Has phosphorylcholine-binding activity (By similarity)..
• Protein Sequence: MTRWSSYLLGWTTFLLYSYESSGGMHEECVFPFTYKGSVYFTCTHIHSLSPWCATRAVYNGQWKYCQSEDYPRCIFPFIYRGKAYNSCISQGSFLGSLWCSVTSVFDEKQQWKFCETNEYGGNSLRKPCIFPSIYRNNVVSDCMEDESNKLWCPTTENMDKDGKWSFCADTRISALVPGFPCHFPFNYKNKNYFNCTNEGSKENLVWCATSYNYDQDHTWVYC

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
64	Acetylation	AVYNGQWKYCQSEDY HHHCCCCCEECCCCC	28.41	25038526
155	Phosphorylation	SNKLWCPTTENMDKD CCCEECCCCCCCCCC	43.54	-
156	Phosphorylation	NKLWCPTTENMDKDG CCEECCCCCCCCCCC	15.54	-
195	N-linked_Glycosylation	YKNKNYFNCTNEGSK CCCCCCEECCCCCCH	22.73	UniProtKB CARBOHYD

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ESPB1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ESPB1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ESPB1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ID3_RAT	Id3	physical	9013644
ID1_RAT	Id1	physical	9013644
UBC9_RAT	Ube2i	physical	9013644
ESPB1_HUMAN	ELSPBP1	physical	9372912
MYOD1_HUMAN	MYOD1	physical	9372912

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.