dbPTM

CSUP_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CSUP_DROME
UniProt AC	Q9V3A4
Protein Name	Protein catecholamines up
Gene Name	Catsup
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	449
Subcellular Localization	Membrane Multi-pass membrane protein .
Protein Description	Negatively regulates tyrosine hydroxylase activity..
Protein Sequence	MAKQVADYQCSKLQLYQKLALVVILGAVLFSLPALCAGQGNPSFKYSREANENFDPQKAPRAEHHHHHDHDHDHGHHHHGHDHDHDHDHGHDHGHHHHGHDHDHDHDHGHHHHGHDERHTKAKPDLDMSTIWLHSIGSTLLISAAPFVLLYIIPLDNSEAMKPRLKVLLAFASGGLLGDAFLHLIPHATHPHSHGEHGHDHGHDHHHHHDGEEHEHGHSHDMSIGLWVLGGIIAFLSVEKLVRILKGGHGGHGHSHGAPKPKPVPAKKKSSDKEDSGDGDKPAKPAKIKSKKPEAEPEGEVEISGYLNLAADFAHNFTDGLAIGASYLAGNSIGIVTTITILLHEVPHEIGDFAILIKSGCSRRKAMLLQLVTALGALAGTALALLGAGGGDGSAPWVLPFTAGGFIYIATVSVLPELLEESTKLKQSLKEIFALLTGVALMIVIAKFE

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
270	Phosphorylation	PVPAKKKSSDKEDSG CCCCCCCCCCCCCCC	53.28	19429919
271	Phosphorylation	VPAKKKSSDKEDSGD CCCCCCCCCCCCCCC	62.68	19429919
276	Phosphorylation	KSSDKEDSGDGDKPA CCCCCCCCCCCCCCC	39.62	19429919
316	N-linked_Glycosylation	LAADFAHNFTDGLAI HHHHHHHHHCCCCHH	37.78	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CSUP_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CSUP_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CSUP_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GCH1_DROME	Pu	genetic	17585895
FGFR2_DROME	btl	genetic	17585895
NDKA_DROME	awd	genetic	17585895
GCH1_DROME	Pu	physical	21985068
TY3H_DROME	ple	physical	21985068

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CSUP_DROME

Related Literatures of Post-Translational Modification