CRK37_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CRK37_ARATH
• UniProt AC: Q9XEC7
• Protein Name: Cysteine-rich receptor-like protein kinase 37
• Gene Name: CRK37
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 646
• Subcellular Localization: Membrane ; Single-pass membrane protein .
• Protein Sequence: MGKSCVVTSSFSLLLLFLQTLKYVHAGFICYGDFFNVNYGVSRTYLFSSLPSNVVSNGGFYNASFGRDSKNNRVHVVALCRRGYEKQACKTCLEHVIEDTKSKCPRQKESFSWVTDEFDDVSCSLRYTNHSTLGKLELLPNTINPNPNSIDSKFNNMAMFSQEWIAMVNRTLEAASTAENSSVLKYYSATRTEFTQISDVYALMQCVPDLSPGNCKRCLRECVNDFQKQFWGRQGGGVSRPSCYFRWDLYPYYRAFDNVVRVPAPPPQASSTIIDYGRDEKSFQGSNIAIIVVPSVINLIIFVVLIFSWKRKQSHTIINDVFDSNNGQSMLRFDLRMIVTATNNFSLENKLGQGGFGSVYKGILPSGQEIAVKRLRKGSGQGGMEFKNEVLLLTRLQHRNLVKLLGFCNEKDEEILVYEFVPNSSLDHFIFDEEKRRVLTWDVRYTIIEGVARGLLYLHEDSQLRIIHRDLKASNILLDAEMNPKVADFGMARLFDMDETRGQTSRVVGTYGYMAPEYATYGQFSTKSDVYSFGVMLLEMISGKSNKKLEKEEEEEEEELPAFVWKRWIEGRFAEIIDPLAAPSNNISINEVMKLIHIGLLCVQEDISKRPSINSILFWLERHATITMPVPTPVAYLTRPSLSLGH

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
62	N-linked_Glycosylation	VSNGGFYNASFGRDS ECCCCCCCCCCCCCC	27.18	-
129	N-linked_Glycosylation	SCSLRYTNHSTLGKL EEEEEECCCCCCCEE	20.41	-
169	N-linked_Glycosylation	QEWIAMVNRTLEAAS HHHHHHHHHHHHHHH	20.38	-
180	N-linked_Glycosylation	EAASTAENSSVLKYY HHHHCCCCCHHHHHE	36.80	-
346	Phosphorylation	VTATNNFSLENKLGQ EEECCCEECCCCCCC	36.58	19880383
418	Phosphorylation	KDEEILVYEFVPNSS CCCEEEEEEECCCCC	10.54	-
474	Phosphorylation	IHRDLKASNILLDAE EECCHHHCCEEECCC	23.86	-
510	Phosphorylation	QTSRVVGTYGYMAPE CCCEEEEECCCCCCC	11.36	-
518	Phosphorylation	YGYMAPEYATYGQFS CCCCCCCCCCCCCCC	11.81	-
643	Phosphorylation	YLTRPSLSLGH---- HHCCCCCCCCC----	36.32	24894044

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CRK37_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CRK37_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CRK37_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
PRA1E_ARATH	PRA1.E	physical	24833385
MSBP2_ARATH	MAPR3	physical	24833385
CP21D_ARATH	AT3G66654	physical	24833385
BETL2_ARATH	AT1G29060	physical	24833385

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.