UniProt ID | CP1A2_HUMAN | |
---|---|---|
UniProt AC | P05177 | |
Protein Name | Cytochrome P450 1A2 | |
Gene Name | CYP1A2 | |
Organism | Homo sapiens (Human). | |
Sequence Length | 515 | |
Subcellular Localization |
Endoplasmic reticulum membrane Peripheral membrane protein. Microsome membrane Peripheral membrane protein. |
|
Protein Description | Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Most active in catalyzing 2-hydroxylation. Caffeine is metabolized primarily by cytochrome CYP1A2 in the liver through an initial N3-demethylation. Also acts in the metabolism of aflatoxin B1 and acetaminophen. Participates in the bioactivation of carcinogenic aromatic and heterocyclic amines. Catalizes the N-hydroxylation of heterocyclic amines and the O-deethylation of phenacetin.. | |
Protein Sequence | MALSQSVPFSATELLLASAIFCLVFWVLKGLRPRVPKGLKSPPEPWGWPLLGHVLTLGKNPHLALSRMSQRYGDVLQIRIGSTPVLVLSRLDTIRQALVRQGDDFKGRPDLYTSTLITDGQSLTFSTDSGPVWAARRRLAQNALNTFSIASDPASSSSCYLEEHVSKEAKALISRLQELMAGPGHFDPYNQVVVSVANVIGAMCFGQHFPESSDEMLSLVKNTHEFVETASSGNPLDFFPILRYLPNPALQRFKAFNQRFLWFLQKTVQEHYQDFDKNSVRDITGALFKHSKKGPRASGNLIPQEKIVNLVNDIFGAGFDTVTTAISWSLMYLVTKPEIQRKIQKELDTVIGRERRPRLSDRPQLPYLEAFILETFRHSSFLPFTIPHSTTRDTTLNGFYIPKKCCVFVNQWQVNHDPELWEDPSEFRPERFLTADGTAINKPLSEKMMLFGMGKRRCIGEVLAKWEIFLFLAILLQQLEFSVPPGVKVDLTPIYGLTMKHARCEHVQARRFSIN | |
Overview of Protein Modification Sites with Functional and Structural Information | ||
* ASA = Accessible Surface Area
Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
---|---|---|---|---|---|
66 | Phosphorylation | KNPHLALSRMSQRYG CCHHHHHHHHHHHHC | 21.96 | 24719451 | |
69 | O-linked_Glycosylation | HLALSRMSQRYGDVL HHHHHHHHHHHCCEE | 15.47 | UniProtKB CARBOHYD | |
72 | Phosphorylation | LSRMSQRYGDVLQIR HHHHHHHHCCEEEEE | 15.27 | - | |
82 | Phosphorylation | VLQIRIGSTPVLVLS EEEEEECCCCEEEEE | 27.45 | 20166139 | |
83 | Phosphorylation | LQIRIGSTPVLVLSR EEEEECCCCEEEEEC | 16.53 | 25072903 | |
89 | Phosphorylation | STPVLVLSRLDTIRQ CCCEEEEECHHHHHH | 24.26 | 24719451 | |
218 | Phosphorylation | ESSDEMLSLVKNTHE CCHHHHHHHHHCHHH | 29.79 | 24719451 | |
267 | Phosphorylation | FLWFLQKTVQEHYQD HHHHHHHHHHHHHHH | 17.92 | 28290473 | |
272 | Phosphorylation | QKTVQEHYQDFDKNS HHHHHHHHHHCCCCC | 14.71 | - | |
279 | Phosphorylation | YQDFDKNSVRDITGA HHHCCCCCHHHHHHH | 25.03 | 24275569 | |
298 | Phosphorylation | SKKGPRASGNLIPQE CCCCCCCCCCCCCHH | 29.50 | 22798277 | |
349 | Phosphorylation | KIQKELDTVIGRERR HHHHHHHHHHCCCCC | 27.01 | - | |
360 | Phosphorylation | RERRPRLSDRPQLPY CCCCCCCCCCCCCHH | 32.62 | 23532336 | |
438 | Phosphorylation | RFLTADGTAINKPLS HHCCCCCCCCCCCCH | 25.55 | - |
Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of CP1A2_HUMAN !! |
Modified Location | Modified Residue | Modification | Function | Reference | ||
---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of CP1A2_HUMAN !! |
* Distance = the distance between SAP position and PTM sites.
Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of CP1A2_HUMAN !! |
Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
---|---|---|---|---|
NCPR_HUMAN | POR | physical | 15680923 | |
CP1A2_HUMAN | CYP1A2 | physical | 22738171 | |
ASAH1_HUMAN | ASAH1 | physical | 28514442 | |
EPHA4_HUMAN | EPHA4 | physical | 28514442 | |
HEMH_HUMAN | FECH | physical | 28514442 | |
PGRC1_HUMAN | PGRMC1 | physical | 28514442 |
Kegg Disease | |
---|---|
There are no disease associations of PTM sites. | |
OMIM Disease | |
There are no disease associations of PTM sites. | |
Kegg Drug | |
D00085 | Insulin (JAN/USP) |
D00105 | Estradiol (JAN/USP/INN); Climara (TN); Divigel (TN); Estrace (TN); Estraderm (TN); Estrasorb (TN); E |
D00118 | Naproxen (JP16/USP/INN); Naprosyn (TN) |
D00131 | Disulfiram (JP16/USP/INN); Antabuse (TN) |
D00136 | Haloperidol (JP16/USP/INN); Haldol (TN) |
D00139 | Methoxsalen (JP16/USP); Oxsoralen (TN) |
D00186 | Ciprofloxacin (JAN/USP/INN); CPFX; Cipro (TN) |
D00210 | Norfloxacin (JP16/USP/INN); NFLX; Noroxin (TN) |
D00217 | Acetaminophen (JP16/USP); Paracetamol (INN); Tylenol (TN) |
D00228 | Amoxapine (JP16/USP/INN); Asendin (TN) |
D00255 | Carvedilol (JAN/USAN/INN); Artist (TN); Coreg (TN) |
D00283 | Clozapine (JAN/USP/INN); Clozaril (TN) |
D00295 | Cimetidine (JP16/USP/INN); Tagamet (TN) |
D00310 | Enoxacin (USAN/INN); ENX; Penetrex (TN) |
D00318 | Famotidine (JP16/USP/INN); Fluxid (TN); Pepcid (TN) |
D00358 | Lidocaine (JP16/USP/INN); Dentipatch (TN); Xylocaine (TN) |
D00371 | Theophylline (JP16); Elixophyllin (TN); Quibron-t (TN); Theo-24 (TN); Theodur G (TN); Theolair (TN); |
D00372 | Tiabendazole (JAN/INN); Thiabendazole (USP); Mintezol (TN) |
D00414 | Zileuton (USP/INN); Zyflo (TN) |
D00415 | Zolmitriptan (JAN/USAN/INN); Zomig (TN) |
D00454 | Olanzapine (JAN/USAN/INN); Zyprexa (TN) |
D00455 | Omeprazole (JP16/USP/INN); Prilosec (TN) |
D00456 | Ondansetron (JAN/USP/INN); Zofran ODT (TN) |
D00483 | Propranolol hydrochloride (JP16/USP); Inderal (TN); Innopran XL (TN) |
D00506 | Phenobarbital (JP16/USP/INN); Luminal (TN) |
D00512 | Phenytoin (JP16/USP/INN); Dilantin (TN) |
D00528 | Anhydrous caffeine (JP16); Caffeine (USP); Anhydrous caffeine (TN) |
D00529 | Montelukast sodium (JAN/USAN); Singulair (TN) |
D00560 | Pimozide (JP16/USP/INN); Orap (TN) |
D00563 | Mirtazapine (JAN/USAN/INN); Remeron (TN); Reflex (TN) |
D00564 | Warfarin sodium (USP); Coumadin (TN); Jantoven (TN) |
D00569 | Phenacetin (JAN/INN) |
D00619 | Verapamil hydrochloride (JP16/USP); Calan (TN); Covera-hs (TN); Vasolan (TN); Verelan (TN) |
D00636 | Amiodarone hydrochloride (JP16/USAN); Ancaron (TN); Cordarone (TN) |
D00639 | Mexiletine hydrochloride (JP16/USP); Mexitil (TN) |
D00640 | Propafenone hydrochloride (JP16/USP); Rythmol (TN) |
D00674 | Naratriptan hydrochloride (JAN/USAN); Amerge (TN) |
D00678 | Ondansetron hydrochloride hydrate (JAN/USP); Ondansetron hydrochloride; Zofran (TN) |
D00701 | Phenobarbital sodium (JAN/USP/INN); Luminal sodium (TN) |
D00706 | Zolpidem tartrate (JP16/USAN); Ambien (TN); Intermezzo (TN) |
D00769 | Clopidogrel sulfate (JAN); Clopidogrel bisulfate (USAN); Isocover (TN); Plavix (TN) |
D00771 | Chlorzoxazone (JAN/USP/INN); Paraflex (TN) |
D00772 | Cyclobenzaprine hydrochloride (USP); Flexeril (TN) |
D00775 | Riluzole (JAN/USAN/INN); Rilutek (TN) |
D00776 | Tizanidine hydrochloride (JP16/USAN); Zanaflex (TN) |
D00784 | Ropinirole hydrochloride (JAN/USAN); Requip (TN) |
D00809 | Amitriptyline hydrochloride (JP16/USP); Elavil (TN) |
D00811 | Clomipramine hydrochloride (JP16/USP); Anafranil (TN) |
D00815 | Imipramine hydrochloride (JP16/USP); Tofranil (TN) |
D00824 | Fluvoxamine maleate (JP16/USAN); Luvox (TN) |
D00928 | Nafcillin sodium (USP); Nafcillin sodium monohydrate; Unipen (TN) |
D00960 | Anastrozole (JAN/USAN/INN); Arimidex (TN) |
D00970 | Naproxen sodium (USP); Anaprox (TN) |
D01028 | Ticlopidine hydrochloride (JP16/USAN); Ticlid (TN) |
D01179 | Duloxetine hydrochloride (JAN/USAN); Cymbalta (TN) |
D01207 | Omeprazole sodium (USAN); Losec sodium (TN) |
D01224 | Phenylpropanolamine hydrochloride (JAN/USP) |
D01280 | Warfarin potassium (JP16); Athrombin-K (TN) |
D01287 | Levobupivacaine hydrochloride (JAN/USAN); Chirocaine (TN) |
D01358 | Mianserin hydrochloride (JAN/USAN); Tetramide (TN) |
D01453 | Caffeine hydrate (JP16); Caffeine monohydrate; Caffeine (TN) |
D01531 | Pipemidic acid hydrate (JP16); PPA; Karunomazin (TN) |
D01583 | Pirfenidone (JAN/USAN/INN); Esbriet (TN) |
D01624 | Sarpogrelate hydrochloride (JP16); Anplag (TN) |
D01776 | Antipyrine (JP16/USP); Phenazone (INN) |
D01832 | Modafinil (JAN/USAN/INN); Provigil (TN) |
D01898 | Haloperidol decanoate (JAN/USAN); Halomonth (TN) |
D01984 | Esomeprazole magnesium hydrate (JAN); Esomeprazole magnesium (USAN); Nexium (TN) |
D02016 | Ramosetron hydrochloride (JAN); YM 060; Nasea (TN) |
D02017 | Choline theophylline (JAN); Oxtriphylline (USP); Choline theophyllinate (INN); Theophyline - choline |
D02068 | Tacrine hydrochloride (USP); Cognex (TN) |
D02086 | Lidocaine injection (JP16); Lidocaine hydrochloride (JAN/USP); Dalcaine (TN); Xylocaine (TN) |
D02087 | Moricizine hydrochloride (USP); Ethmozine (TN) |
D02103 | Phenytoin sodium for injection (JP16); Phenytoin sodium (USP); Aleviatin (TN); Dilantin (TN) |
D02216 | Ciprofloxacin hydrochloride (JAN/USP); CPFX; Ciloxan (TN); Cipro (TN); Proquin XR (TN) |
D02219 | Terbinafine hydrochloride (JP16/USP); Lamisil (TN) |
D02274 | Dantrolene sodium hydrate (JP16); Dantrolene sodium (USAN); Dantrium (TN) |
D02347 | Dantrolene (USAN/INN) |
D02356 | Verapamil (USAN/INN) |
D02375 | Terbinafine (USAN/INN); Lamasil (TN) |
D02497 | Fosamprenavir (INN) |
D02689 | Ramelteon (JAN/USAN/INN); Rozerem (TN) |
D02829 | Alosetron hydrochloride (USAN); Lotrpnex (TN) |
D02867 | Fosamprenavir calcium hydrate (JAN); Lexiva (TN) |
D02910 | Amiodarone (USAN/INN) |
D03150 | Bortezomib (JAN/USAN/INN); Velcade (TN) |
D03215 | Armodafinil (USAN/INN); Nuvigil (TN) |
D03230 | Insulin human (genetical recombination) (JP16); Insulin human (biosynthesis) (JAN); Insulin human (s |
D03250 | Insulin glargine (genetical recombination) (JAN); Insulin glargine (USAN/INN); Lantus (TN) |
D03365 | Nicotine (USP); Habitrol (TN) |
D03415 | Carvedilol phosphate hydrate (JAN); Carvedilol phosphate (USAN); Coreg CR (TN) |
D03503 | Cimetidine hydrochloride (USP); Cimetidine hydrochloride (TN) |
D03669 | Deferasirox (JAN/USAN/INN); Exjade (TN) |
D03729 | Dexpropranolol hydrochloride (USAN) |
D03835 | Fosamprenavir calcium (USAN); Lexiva (TN) |
D03837 | Fosamprenavir sodium (USAN) |
D03978 | Eltrombopag olamine (JAN/USAN); Promacta (TN) |
D04023 | Erlotinib hydrochloride (JAN/USAN); Tarceva (TN) |
D04048 | Ropivacaine hydrochloride hydrate (JAN); Ropivacaine hydrochloride (USP); Anapeine (TN) |
D04052 | Adrenaline - lidocaine hydrochloride mixt; Epinephrine - lidocaine hydrochloride mixt; Xylocaine (TN |
D04056 | Esomeprazole sodium (USAN); Nexium IV (TN) |
D04475 | Insulin aspart (genetical recombination) (JAN); Insulin aspart (USAN/INN); Insulin X 14; NovoRapid ( |
D04477 | Insulin lispro (genetical recombination) (JAN); Insulin lispro (USP/INN); Humalog (TN) |
D04539 | Insulin detemir (genetical recombination) (JAN); Insulin detemir (USAN/INN); Levemir (TN) |
D04540 | Insulin glulisine (genetical recombination) (JAN); Insulin glulisine (USAN/INN); Apidra (TN) |
D04541 | Insulin human, isophane (USP) |
D04542 | Insulin human zinc (USP) |
D04543 | Insulin human zinc, extended (USP) |
D04547 | Isophane insulin injection (aqueous suspension) (JAN); Insulin, isophane (USP); Humalog PEN (TN) |
D04548 | Insulin, neutral (USAN); Neutral insulin injection (INN) |
D04549 | Insulin zinc, extended (USP); Ultralente iletin (TN) |
D04550 | Insulin zinc, prompt (USP); Semilente iletin (TN) |
D04551 | Insulin zinc (USP); Lente iletin (TN) |
D04813 | Lidocaine hydrochloride - epinephrine bitartrate mixt; Ora (TN); Lidosite (TN) |
D05024 | Mibefradil dihydrochloride (USAN); Posicor (TN) |
D05077 | Moricizine (USAN); Moracizine (INN) |
D05259 | Omeprazole magnesium (USAN); Prilosec OTC (TN) |
D05261 | Omeprazole sodium injection (JAN); Omeprazole sodium hydrate; Omepral (TN) |
D05343 | Palonocetron hydrochloride (JAN); Palonosetron hydrochloride (USAN); Aloxi (TN) |
D05429 | Aminophylline hydrate (JP16) |
D05461 | Enoxacin hydrate (JP16) |
D05466 | Phenylpropanolamine polistirex (USAN) |
D05622 | Proinsulin human (USAN) |
D05928 | Stiripentol (JAN/USAN/INN) |
D06103 | Theophylline (USP); Theophylline monohydrate; Accurbron (TN) |
D06623 | Olanzapine pamoate (USAN); Olanzapine pamoate monohydrate |
D07129 | Alosetron (INN) |
D07175 | Palonosetron (INN); Aloxi (TN) |
D07448 | Amitriptyline (INN); Laroxyl (TN) |
D07603 | Caffeine citrate (USP); Cafcit (TN) |
D07702 | Ciprofloxacin lactate; Ciproxin (TN) |
D07727 | Clomipramine (INN); Anafranil (TN) |
D07729 | Clopidogrel (INN); Clopidogrel (TN); Plavix (TN) |
D07758 | Cyclobenzaprine (INN) |
D07880 | Duloxetine (INN); Yentreve (TN) |
D07907 | Erlotinib (INN); Tarceva (TN) |
D07917 | Esomeprazole (INN); Inexium paranova (TN) |
D07984 | Fluvoxamine (INN) |
D08070 | Imipramine (INN); Tofranil (TN) |
D08071 | Imipramine embonate; Tofranil-pm (TN) |
D08080 | Insulin injection, biphasic isophane (BAN); Insulin Humacart (TN) |
D08127 | Lidocaine hydrochloride monohydrate; Lidocaine (TN) |
D08170 | Melatonin; Melatonina (TN) |
D08215 | Mexiletine (INN) |
D08216 | Mianserin (INN); Tolvon (TN) |
D08217 | Mibefradil (INN) |
D08229 | Montelukast (INN); Brondilat (TN) |
D08242 | Nafcillin (INN) |
D08255 | Naratriptan (INN); Naramig (TN) |
D08287 | Norfloxacin nicotinate; Quinabic soluble powder (TN) [veterinary] |
D08356 | Phenobarbital diethylamine; Gratusminal (TN) |
D08368 | Phenylpropanolamine (INN); Fansia (TN) |
D08379 | Pipemidic acid (INN); Nuril (TN) |
D08435 | Propafenone (INN); Propafenon hexal (TN) |
D08443 | Propranolol (INN); Propranolol (TN) |
D08466 | Ramosetron (INN) |
D08489 | Ropinirole (USAN/INN); Ropitor (TN) |
D08490 | Ropivacaine (INN); Naropin (TN) |
D08508 | Sarpogrelate (INN) |
D08555 | Tacrine (INN); Tacrinal (TN) |
D08559 | Tamoxifen (INN); Tamoxifen (TN); Tamoplex (TN) |
D08594 | Ticlopidine (INN); Ticlopidin-Puren (TN) |
D08611 | Tizanidine (INN); Sirdalud (TN) |
D08682 | Warfarin (INN); Warfarine; Choice (TN) |
D08690 | Zolpidem (INN); Sanval (TN) |
D08903 | Dexlansoprazole (INN/USAN) |
D09339 | Esomeprazole potassium (USAN) |
DrugBank | |
DB01418 | Acenocoumarol |
DB00316 | Acetaminophen |
DB06594 | Agomelatine |
DB00518 | Albendazole |
DB00523 | Alitretinoin |
DB00918 | Almotriptan |
DB00969 | Alosetron |
DB00357 | Aminoglutethimide |
DB01424 | Aminophenazone |
DB01223 | Aminophylline |
DB01118 | Amiodarone |
DB00321 | Amitriptyline |
DB00381 | Amlodipine |
DB00261 | Anagrelide |
DB01217 | Anastrozole |
DB01435 | Antipyrine |
DB06605 | Apixaban |
DB00673 | Aprepitant |
DB06216 | Asenapine |
DB00572 | Atropine |
DB06626 | Axitinib |
DB00972 | Azelastine |
DB00207 | Azithromycin |
DB06770 | Benzyl alcohol |
DB00195 | Betaxolol |
DB00188 | Bortezomib |
DB01558 | Bromazepam |
DB01200 | Bromocriptine |
DB00297 | Bupivacaine |
DB00921 | Buprenorphine |
DB01156 | Bupropion |
DB00201 | Caffeine |
DB00564 | Carbamazepine |
DB00262 | Carmustine |
DB01136 | Carvedilol |
DB00477 | Chlorpromazine |
DB00356 | Chlorzoxazone |
DB01166 | Cilostazol |
DB00501 | Cimetidine |
DB01012 | Cinacalcet |
DB00568 | Cinnarizine |
DB00537 | Ciprofloxacin |
DB00604 | Cisapride |
DB00215 | Citalopram |
DB01211 | Clarithromycin |
DB01407 | Clenbuterol |
DB04920 | Clevidipine |
DB01013 | Clobetasol propionate |
DB00882 | Clomifene |
DB01242 | Clomipramine |
DB00575 | Clonidine |
DB00758 | Clopidogrel |
DB00257 | Clotrimazole |
DB00363 | Clozapine |
DB00286 | Conjugated Estrogens |
DB00924 | Cyclobenzaprine |
DB00851 | Dacarbazine |
DB06292 | Dapagliflozin |
DB01254 | Dasatinib |
DB00694 | Daunorubicin |
DB00705 | Delavirdine |
DB01151 | Desipramine |
DB00967 | Desloratadine |
DB01191 | Dexfenfluramine |
DB00633 | Dexmedetomidine |
DB00829 | Diazepam |
DB00586 | Diclofenac |
DB00917 | Dinoprostone |
DB01075 | Diphenhydramine |
DB01184 | Domperidone |
DB00988 | Dopamine |
DB01142 | Doxepin |
DB00476 | Duloxetine |
DB00974 | Edetic Acid |
DB00625 | Efavirenz |
DB06210 | Eltrombopag |
DB00467 | Enoxacin |
DB00668 | Epinephrine |
DB00696 | Ergotamine |
DB00530 | Erlotinib |
DB00199 | Erythromycin |
DB00783 | Estradiol |
DB00655 | Estrone |
DB04574 | Estropipate |
DB00898 | Ethanol |
DB00773 | Etoposide |
DB01628 | Etoricoxib |
DB04841 | Flunarizine |
DB01544 | Flunitrazepam |
DB00544 | Fluorouracil |
DB00472 | Fluoxetine |
DB00623 | Fluphenazine |
DB00499 | Flutamide |
DB01095 | Fluvastatin |
DB00176 | Fluvoxamine |
DB00998 | Frovatriptan |
DB01241 | Gemfibrozil |
DB00400 | Griseofulvin |
DB00629 | Guanabenz |
DB00502 | Haloperidol |
DB01094 | Hesperetin |
DB01355 | Hexobarbital |
DB04946 | Iloperidone |
DB00619 | Imatinib |
DB00458 | Imipramine |
DB00724 | Imiquimod |
DB05278 | inhaled insulin |
DB01306 | Insulin Aspart |
DB01307 | Insulin Detemir |
DB00047 | Insulin Glargine |
DB01309 | Insulin Glulisine |
DB00046 | Insulin Lispro |
DB00030 | Insulin Regular |
DB01029 | Irbesartan |
DB00951 | Isoniazid |
DB01026 | Ketoconazole |
DB00448 | Lansoprazole |
DB01097 | Leflunomide |
DB01002 | Levobupivacaine |
DB01137 | Levofloxacin |
DB00281 | Lidocaine |
DB00978 | Lomefloxacin |
DB01601 | Lopinavir |
DB04871 | Lorcaserin |
DB00678 | Losartan |
DB01283 | Lumiracoxib |
DB00772 | Malathion |
DB00934 | Maprotiline |
DB00737 | Meclizine |
DB01065 | Melatonin |
DB00170 | Menadione |
DB00333 | Methadone |
DB00763 | Methimazole |
DB01403 | Methotrimeprazine |
DB00553 | Methoxsalen |
DB01028 | Methoxyflurane |
DB00379 | Mexiletine |
DB06148 | Mianserin |
DB01110 | Miconazole |
DB00370 | Mirtazapine |
DB01171 | Moclobemide |
DB00745 | Modafinil |
DB00461 | Nabumetone |
DB00607 | Nafcillin |
DB00788 | Naproxen |
DB00220 | Nelfinavir |
DB00238 | Nevirapine |
DB06803 | Niclosamide |
DB00184 | Nicotine |
DB01115 | Nifedipine |
DB06712 | Nilvadipine |
DB00401 | Nisoldipine |
DB00435 | Nitric Oxide |
DB00325 | Nitroprusside |
DB00368 | Norepinephrine |
DB01059 | Norfloxacin |
DB00540 | Nortriptyline |
DB01165 | Ofloxacin |
DB00334 | Olanzapine |
DB00338 | Omeprazole |
DB00904 | Ondansetron |
DB00526 | Oxaliplatin |
DB01303 | Oxtriphylline |
DB00377 | Palonosetron |
DB00213 | Pantoprazole |
DB06589 | Pazopanib |
DB00487 | Pefloxacin |
DB00738 | Pentamidine |
DB00806 | Pentoxifylline |
DB00850 | Perphenazine |
DB01174 | Phenobarbital |
DB00191 | Phentermine |
DB00388 | Phenylephrine |
DB00397 | Phenylpropanolamine |
DB01100 | Pimozide |
DB01621 | Pipotiazine |
DB08910 | Pomalidomide |
DB01058 | Praziquantel |
DB01087 | Primaquine |
DB00794 | Primidone |
DB00396 | Progesterone |
DB01131 | Proguanil |
DB00420 | Promazine |
DB01182 | Propafenone |
DB00818 | Propofol |
DB00571 | Propranolol |
DB00339 | Pyrazinamide |
DB00908 | Quinidine |
DB00468 | Quinine |
DB01129 | Rabeprazole |
DB00980 | Ramelteon |
DB00863 | Ranitidine |
DB01367 | Rasagiline |
DB00615 | Rifabutin |
DB01045 | Rifampicin |
DB08864 | Rilpivirine |
DB00740 | Riluzole |
DB00503 | Ritonavir |
DB00953 | Rizatriptan |
DB00268 | Ropinirole |
DB00296 | Ropivacaine |
DB00412 | Rosiglitazone |
DB05271 | Rotigotine |
DB00778 | Roxithromycin |
DB00418 | Secobarbital |
DB01037 | Selegiline |
DB01104 | Sertraline |
DB06290 | Simeprevir |
DB00398 | Sorafenib |
DB00428 | Streptozocin |
DB00605 | Sulindac |
DB00675 | Tamoxifen |
DB00976 | Telithromycin |
DB00300 | Tenofovir |
DB00857 | Terbinafine |
DB01041 | Thalidomide |
DB01412 | Theobromine |
DB00277 | Theophylline |
DB00730 | Thiabendazole |
DB00679 | Thioridazine |
DB01623 | Thiothixene |
DB00208 | Ticlopidine |
DB01007 | Tioconazole |
DB00697 | Tizanidine |
DB01056 | Tocainide |
DB00539 | Toremifene |
DB00752 | Tranylcypromine |
DB00384 | Triamterene |
DB00831 | Trifluoperazine |
DB00313 | Valproic Acid |
DB08881 | Vemurafenib |
DB00661 | Verapamil |
DB00682 | Warfarin |
DB00549 | Zafirlukast |
DB00744 | Zileuton |
DB00246 | Ziprasidone |
DB00315 | Zolmitriptan |
DB00425 | Zolpidem |
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