COR2B_HUMAN - dbPTM
COR2B_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID COR2B_HUMAN
UniProt AC Q9UQ03
Protein Name Coronin-2B
Gene Name CORO2B
Organism Homo sapiens (Human).
Sequence Length 480
Subcellular Localization Cytoplasm, cytoskeleton .
Protein Description May play a role in the reorganization of neuronal actin structure..
Protein Sequence MTVTKMSWRPQYRSSKFRNVYGKVANREHCFDGIPITKNVHDNHFCAVNTRFLAIVTESAGGGSFLVIPLEQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPEGGLKRNMTEALLELHGHSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDVGEPVKMIDCHTDVILCMSFNTDGSLLTTTCKDKKLRVIEPRSGRVLQEANCKNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPLIEEEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHGLDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGGINRDPVLMSLKEGYKKSSKMVFKAPIKEKKSVVVNGIDLLENVPPRTENELLRMFFRQQDEIRRLKEELAQKDIRIRQLQLELKNLRNSPKNC
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
4Phosphorylation----MTVTKMSWRPQ
----CCCCCCCCCHH		16.3229116813
12PhosphorylationKMSWRPQYRSSKFRN
CCCCCHHHCCCCHHH		18.3629116813
14PhosphorylationSWRPQYRSSKFRNVY
CCCHHHCCCCHHHCH		32.7122964224
77UbiquitinationLEQTGRIEPNYPKVC
HHHCCCCCCCCCCCC		26.5730230243
82UbiquitinationRIEPNYPKVCGHQGN
CCCCCCCCCCCCCCC		39.5330230243
118UbiquitinationSVRIWEIPEGGLKRN
CEEEEECCCCCCCCC		23.7530230243
123UbiquitinationEIPEGGLKRNMTEAL
ECCCCCCCCCHHHHH		45.0330230243
127PhosphorylationGGLKRNMTEALLELH
CCCCCCHHHHHHHHH		22.96-
216UbiquitinationPRSGRVLQEANCKNH
CCCCCCCHHHCCCCC		44.9230230243
221UbiquitinationVLQEANCKNHRVNRV
CCHHHCCCCCCCCEE		56.4430230243
315PhosphorylationSYLMEFRSPAPQKGL
HHHHHCCCCCCCCCC		30.6328857561
315UbiquitinationSYLMEFRSPAPQKGL
HHHHHCCCCCCCCCC		30.6330230243
320UbiquitinationFRSPAPQKGLGVMPK
CCCCCCCCCCCCCCC		55.8530230243
322UbiquitinationSPAPQKGLGVMPKHG
CCCCCCCCCCCCCCC		6.3530230243
327UbiquitinationKGLGVMPKHGLDVSA
CCCCCCCCCCCCHHH		32.0130230243
402AcetylationMSLKEGYKKSSKMVF
HHHHHCCHHCCCEEE		57.9718525613
403AcetylationSLKEGYKKSSKMVFK
HHHHCCHHCCCEEEE		52.0218525623
406AcetylationEGYKKSSKMVFKAPI
HCCHHCCCEEEECCC		46.2919812211
410AcetylationKSSKMVFKAPIKEKK
HCCCEEEECCCCCCC		41.6719812221
416AcetylationFKAPIKEKKSVVVNG
EECCCCCCCEEEEEC		45.4019812231
418PhosphorylationAPIKEKKSVVVNGID
CCCCCCCEEEEECEE		31.08-
466UbiquitinationKDIRIRQLQLELKNL
HCHHHHHHHHHHHHH		4.5130230243
471UbiquitinationRQLQLELKNLRNSPK
HHHHHHHHHHHCCCC		44.5630230243
476PhosphorylationELKNLRNSPKNC---
HHHHHHCCCCCC---		30.7129514088
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of COR2B_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of COR2B_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of COR2B_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
APBP2_HUMANAPPBP2physical
25416956
COR2A_HUMANCORO2Aphysical
28514442
KGP1_HUMANPRKG1physical
28514442
SHC1_HUMANSHC1physical
28514442
ARHGP_HUMANARHGEF25physical
28514442
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of COR2B_HUMAN

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Related Literatures of Post-Translational Modification

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