CK024_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CK024_HUMAN
• UniProt AC: Q96F05
• Protein Name: Uncharacterized protein C11orf24
• Gene Name: C11orf24
• Organism: Homo sapiens (Human).
• Sequence Length: 449
• Subcellular Localization: Cell membrane ; Single-pass type I membrane protein . Golgi apparatus, trans-Golgi network membrane ; Single-pass type I membrane protein . Cycles to the plasma membrane via endosomes in a pH sensitive manner. Associated with Rab6-positive vesicles.
• Protein Sequence: MWTALVLIWIFSLSLSESHAASNDPRNFVPNKMWKGLVKRNASVETVDNKTSEDVTMAAASPVTLTKGTSAAHLNSMEVTTEDTSRTDVSEPATSGGAADGVTSIAPTAVASSTTAASITTAASSMTVASSAPTTAASSTTVASIAPTTAASSMTAASSTPMTLALPAPTSTSTGRTPSTTATGHPSLSTALAQVPKSSALPRTATLATLATRAQTVATTANTSSPMSTRPSPSKHMPSDTAASPVPPMRPQAQGPISQVSVDQPVVNTTNKSTPMPSNTTPEPAPTPTVVTTTKAQAREPTASPVPVPHTSPIPEMEAMSPTTQPSPMPYTQRAAGPGTSQAPEQVETEATPGTDSTGPTPRSSGGTKMPATDSCQPSTQGQYMVVTTEPLTQAVVDKTLLLVVLLLGVTLFITVLVLFALQAYESYKKKDYTQVDYLINGMYADSEM

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
43	Phosphorylation	GLVKRNASVETVDNK HHHHCCCCEEEECCC	24.84	25159151
46	Phosphorylation	KRNASVETVDNKTSE HCCCCEEEECCCCCC	30.88	29514088
49	N-linked_Glycosylation	ASVETVDNKTSEDVT CCEEEECCCCCCCCH	45.21	UniProtKB CARBOHYD
56	O-linked_Glycosylation	NKTSEDVTMAAASPV CCCCCCCHHHCCCCE	17.26	OGP
61	Phosphorylation	DVTMAAASPVTLTKG CCHHHCCCCEEECCC	18.38	25627689
64	O-linked_Glycosylation	MAAASPVTLTKGTSA HHCCCCEEECCCCCC	31.90	OGP
66	O-linked_Glycosylation	AASPVTLTKGTSAAH CCCCEEECCCCCCHH	20.33	OGP
69	O-linked_Glycosylation	PVTLTKGTSAAHLNS CEEECCCCCCHHHCC	19.42	OGP
69	Phosphorylation	PVTLTKGTSAAHLNS CEEECCCCCCHHHCC	19.42	27251275
70	Phosphorylation	VTLTKGTSAAHLNSM EEECCCCCCHHHCCC	31.93	27251275
80	O-linked_Glycosylation	HLNSMEVTTEDTSRT HHCCCEEECCCCCCC	15.91	OGP
81	O-linked_Glycosylation	LNSMEVTTEDTSRTD HCCCEEECCCCCCCC	36.72	OGP
87	Phosphorylation	TTEDTSRTDVSEPAT ECCCCCCCCCCCCCC	40.29	-
90	Phosphorylation	DTSRTDVSEPATSGG CCCCCCCCCCCCCCC	40.44	-
179	O-linked_Glycosylation	TSTGRTPSTTATGHP CCCCCCCCCCCCCCC	37.46	OGP
189	O-linked_Glycosylation	ATGHPSLSTALAQVP CCCCCCHHHHHHHCC	18.90	OGP
190	O-linked_Glycosylation	TGHPSLSTALAQVPK CCCCCHHHHHHHCCC	30.86	OGP
199	Phosphorylation	LAQVPKSSALPRTAT HHHCCCCCCCCHHHH	39.69	24719451
204	Phosphorylation	KSSALPRTATLATLA CCCCCCHHHHHHHHH	23.27	26552605
204	O-linked_Glycosylation	KSSALPRTATLATLA CCCCCCHHHHHHHHH	23.27	10508707
206	O-linked_Glycosylation	SALPRTATLATLATR CCCCHHHHHHHHHHH	19.13	55833833
206	Phosphorylation	SALPRTATLATLATR CCCCHHHHHHHHHHH	19.13	26552605
209	O-linked_Glycosylation	PRTATLATLATRAQT CHHHHHHHHHHHHHH	21.75	55833837
209	Phosphorylation	PRTATLATLATRAQT CHHHHHHHHHHHHHH	21.75	26552605
212	O-linked_Glycosylation	ATLATLATRAQTVAT HHHHHHHHHHHHHHH	29.65	10508717
212	Phosphorylation	ATLATLATRAQTVAT HHHHHHHHHHHHHHH	29.65	26552605
216	Phosphorylation	TLATRAQTVATTANT HHHHHHHHHHHCCCC	15.89	26552605
219	Phosphorylation	TRAQTVATTANTSSP HHHHHHHHCCCCCCC	23.31	26552605
220	Phosphorylation	RAQTVATTANTSSPM HHHHHHHCCCCCCCC	14.26	26552605
223	Phosphorylation	TVATTANTSSPMSTR HHHHCCCCCCCCCCC	28.28	26552605
224	Phosphorylation	VATTANTSSPMSTRP HHHCCCCCCCCCCCC	32.05	26552605
225	Phosphorylation	ATTANTSSPMSTRPS HHCCCCCCCCCCCCC	23.68	26552605
228	Phosphorylation	ANTSSPMSTRPSPSK CCCCCCCCCCCCCCC	25.34	23186163
229	Phosphorylation	NTSSPMSTRPSPSKH CCCCCCCCCCCCCCC	40.11	26552605
232	Phosphorylation	SPMSTRPSPSKHMPS CCCCCCCCCCCCCCC	38.22	23917254
234	Phosphorylation	MSTRPSPSKHMPSDT CCCCCCCCCCCCCCC	39.26	23186163
244	Phosphorylation	MPSDTAASPVPPMRP CCCCCCCCCCCCCCC	24.78	25627689
278	Phosphorylation	NKSTPMPSNTTPEPA CCCCCCCCCCCCCCC	40.32	25627689
304	O-linked_Glycosylation	QAREPTASPVPVPHT CCCCCCCCCCCCCCC	28.98	OGP
311	Phosphorylation	SPVPVPHTSPIPEME CCCCCCCCCCCCCHH	30.08	30576142
312	Phosphorylation	PVPVPHTSPIPEMEA CCCCCCCCCCCCHHC	20.14	25332170
332	Phosphorylation	QPSPMPYTQRAAGPG CCCCCCCCCCCCCCC	13.00	30576142
357	Phosphorylation	EATPGTDSTGPTPRS CCCCCCCCCCCCCCC	34.79	28555341
433	Phosphorylation	ESYKKKDYTQVDYLI HHHCCCCCHHHHHHH	14.14	-
444	Phosphorylation	DYLINGMYADSEM-- HHHHCCCCCCCCC--	14.51	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CK024_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CK024_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CK024_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
VAT1L_HUMAN	VAT1L	physical	28514442
RN166_HUMAN	RNF166	physical	28514442
VWA1_HUMAN	VWA1	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.