dbPTM

CF161_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	CF161_HUMAN
UniProt AC	Q6P656
Protein Name	Cilia- and flagella-associated protein 161 {ECO:0000312\|HGNC:HGNC:26782}
Gene Name	CFAP161 {ECO:0000312\|HGNC:HGNC:26782}
Organism	Homo sapiens (Human).
Sequence Length	301
Subcellular Localization
Protein Description	May play a role in motile cilia function, possibly by acting on dynein arm assembly..
Protein Sequence	MAQNVYGPGVRIGNWNEDVYLEEELMKDFLEKRDKGKLLIQRSRRLKQNLLRPMQLSVTEDGYIHYGDKVMLVNPDDPDTEADVFLRGDLSLCMTPDEIQSHLKDELEVPCGLSAVQAKTPIGRNTFIILSVHRDATGQVLRYGQDFCLGITGGFDNKMLYLSSDHRTLLKSSKRSWLQEVYLTDEVSHVNCWQAAFPDPQLRLEYEGFPVPANAKILINHCHTNRGLAAHRHLFLSTYFGKEAEVVAHTYLDSHRVEKPRNHWMLVTGNPRDASSSMLDLPKPPTEDTRAMEQAMGLDTQ

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	Reference
143	Phosphorylation	ATGQVLRYGQDFCLG CCCCEEEECCCEEEE	-
161	Phosphorylation	GFDNKMLYLSSDHRT CCCCCEEEECCCHHH	-
275	Phosphorylation	TGNPRDASSSMLDLP ECCCCCCCCCCCCCC	-
286	Phosphorylation	LDLPKPPTEDTRAME CCCCCCCCHHHHHHH	-
289	Phosphorylation	PKPPTEDTRAMEQAM CCCCCHHHHHHHHHH	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of CF161_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of CF161_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of CF161_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EMAL5_HUMAN	EML5	physical	27173435
SPA5L_HUMAN	SPATA5L1	physical	27173435
MRE11_HUMAN	MRE11A	physical	27173435
SPAT5_HUMAN	SPATA5	physical	27173435
BUB1_HUMAN	BUB1	physical	27173435

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of CF161_HUMAN

Related Literatures of Post-Translational Modification