CCL7_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: CCL7_HUMAN
• UniProt AC: P80098
• Protein Name: C-C motif chemokine 7
• Gene Name: CCL7
• Organism: Homo sapiens (Human).
• Sequence Length: 99
• Subcellular Localization: Secreted.
• Protein Description: Chemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3..
• Protein Sequence: MKASAALLCLLLTAAAFSPQGLAQPVGINTSTTCCYRFINKKIPKQRLESYRRTTSSHCPREAVIFKTKLDKEICADPTQKWVQDFMKHLDKKTQTPKL

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
24	Pyrrolidone_carboxylic_acid	FSPQGLAQPVGINTS HCCCCCCCCCCCCCC	37.95	-
24	Pyrrolidone_carboxylic_acid	FSPQGLAQPVGINTS HCCCCCCCCCCCCCC	37.95	15340161
24	Pyrrolidone_carboxylic_acid	FSPQGLAQPVGINTS HCCCCCCCCCCCCCC	37.95	15340161
29	N-linked_Glycosylation	LAQPVGINTSTTCCY CCCCCCCCCCCCHHH	23.27	UniProtKB CARBOHYD
54	Phosphorylation	RLESYRRTTSSHCPR HHHHHHHHCCCCCCC	23.25	30206219
55	Phosphorylation	LESYRRTTSSHCPRE HHHHHHHCCCCCCCC	26.81	30206219
56	Phosphorylation	ESYRRTTSSHCPREA HHHHHHCCCCCCCCC	19.92	30206219
57	Phosphorylation	SYRRTTSSHCPREAV HHHHHCCCCCCCCCE	27.32	30206219
94	Phosphorylation	MKHLDKKTQTPKL-- HHHHHHHCCCCCC--	43.33	30576142
96	Phosphorylation	HLDKKTQTPKL---- HHHHHCCCCCC----	27.85	30576142

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of CCL7_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of CCL7_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of CCL7_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FEZ1_HUMAN	FEZ1	physical	16169070
CCL7_HUMAN	CCL7	physical	9109648
UBQL1_HUMAN	UBQLN1	physical	25416956

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.