CCD91_HUMAN - dbPTM
CCD91_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID CCD91_HUMAN
UniProt AC Q7Z6B0
Protein Name Coiled-coil domain-containing protein 91
Gene Name CCDC91
Organism Homo sapiens (Human).
Sequence Length 441
Subcellular Localization Membrane
Peripheral membrane protein . Golgi apparatus, trans-Golgi network membrane
Peripheral membrane protein . Golgi apparatus, trans-Golgi network . Colocalizes with GGA1, GGA2 and GGA3.
Protein Description Involved in the regulation of membrane traffic through the trans-Golgi network (TGN). Functions in close cooperation with the GGAs in the sorting of hydrolases to lysosomes..
Protein Sequence MDDDDFGGFEAAETFDGGSGETQTTSPAIPWAAFPAVSGVHLSPSSPEIVLDRDHSSSIGCLSSDAIISSPENTHAANSIVSQTIPKAQIQQSTHTHLDISLFPLGLTDEKSNGTIALVDDSEDPGANVSNIQLQQKISSLEIKLKVSEEEKQRIKQDVESLMEKHNVLEKGFLKEKEQEAISFQDRYKELQEKHKQELEDMRKAGHEALSIIVDEYKALLQSSVKQQVEAIEKQYISAIEKQAHKCEELLNAQHQRLLEMLDTEKELLKEKIKEALIQQSQEQKEILEKCLEEERQRNKEALVSAAKLEKEAVKDAVLKVVEEERKNLEKAHAEERELWKTEHAKDQEKVSQEIQKAIQEQRKISQETVKAAIIEEQKRSEKAVEEAVKRTRDELIEYIKEQKRLDQVIRQRSLSSLELFLSCAQKQLSALIATEPVDIE
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
15 (in isoform 2)Phosphorylation-6.5525159151
16 (in isoform 2)Phosphorylation-68.8825159151
43PhosphorylationAVSGVHLSPSSPEIV
CCCCEEECCCCCCEE		14.09-
46PhosphorylationGVHLSPSSPEIVLDR
CEEECCCCCCEEECC		29.90-
58PhosphorylationLDRDHSSSIGCLSSD
ECCCCCCCCCCCCCC		26.4721712546
63PhosphorylationSSSIGCLSSDAIISS
CCCCCCCCCCEEECC		30.1927080861
64PhosphorylationSSIGCLSSDAIISSP
CCCCCCCCCEEECCC		20.3627080861
69PhosphorylationLSSDAIISSPENTHA
CCCCEEECCCCCHHH		33.4523663014
70PhosphorylationSSDAIISSPENTHAA
CCCEEECCCCCHHHC		26.3123663014
74PhosphorylationIISSPENTHAANSIV
EECCCCCHHHCHHHH		15.9527080861
79PhosphorylationENTHAANSIVSQTIP
CCHHHCHHHHHCCCC		21.4623663014
82PhosphorylationHAANSIVSQTIPKAQ
HHCHHHHHCCCCHHH		21.6727080861
84PhosphorylationANSIVSQTIPKAQIQ
CHHHHHCCCCHHHHC		31.5727080861
130PhosphorylationEDPGANVSNIQLQQK
CCCCCCCCHHHHHHH		28.2028555341
139PhosphorylationIQLQQKISSLEIKLK
HHHHHHHHHCEEEEE		35.5923312004
140PhosphorylationQLQQKISSLEIKLKV
HHHHHHHHCEEEEEC		33.2323312004
148PhosphorylationLEIKLKVSEEEKQRI
CEEEEECCHHHHHHH		37.3926074081
161PhosphorylationRIKQDVESLMEKHNV
HHHHHHHHHHHHCCH		32.6326074081
165UbiquitinationDVESLMEKHNVLEKG
HHHHHHHHCCHHHHC		26.89-
171UbiquitinationEKHNVLEKGFLKEKE
HHCCHHHHCCCCHHH		51.29-
223PhosphorylationEYKALLQSSVKQQVE
HHHHHHHHHHHHHHH		36.7528442448
224PhosphorylationYKALLQSSVKQQVEA
HHHHHHHHHHHHHHH		22.0028442448
226UbiquitinationALLQSSVKQQVEAIE
HHHHHHHHHHHHHHH		36.64-
246UbiquitinationAIEKQAHKCEELLNA
HHHHHHHHHHHHHHH		46.48-
264PhosphorylationRLLEMLDTEKELLKE
HHHHHHHHHHHHHHH		45.0230622161
274UbiquitinationELLKEKIKEALIQQS
HHHHHHHHHHHHHHH		48.26-
290UbiquitinationEQKEILEKCLEEERQ
HHHHHHHHHHHHHHH		40.45-
300UbiquitinationEEERQRNKEALVSAA
HHHHHHHHHHHHHHH		46.70-
311UbiquitinationVSAAKLEKEAVKDAV
HHHHHHHHHHHHHHH		62.50-
315AcetylationKLEKEAVKDAVLKVV
HHHHHHHHHHHHHHH		47.2019820999
366PhosphorylationIQEQRKISQETVKAA
HHHHHHCCHHHHHHH		25.6220068231
371UbiquitinationKISQETVKAAIIEEQ
HCCHHHHHHHHHHHH		39.25-
381PhosphorylationIIEEQKRSEKAVEEA
HHHHHHHHHHHHHHH		50.9528674151
414PhosphorylationDQVIRQRSLSSLELF
HHHHHHCCHHHHHHH		25.0221082442
416PhosphorylationVIRQRSLSSLELFLS
HHHHCCHHHHHHHHH		33.8428857561
417PhosphorylationIRQRSLSSLELFLSC
HHHCCHHHHHHHHHH		31.0227273156
430PhosphorylationSCAQKQLSALIATEP
HHHHHHHHHHHHCCC		20.66-
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of CCD91_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of CCD91_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of CCD91_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
CCD91_HUMANCCDC91physical
17596511
GGA1_HUMANGGA1physical
17596511
CCD91_HUMANCCDC91physical
25416956
STAR7_HUMANSTARD7physical
28514442
CJ088_HUMANC10orf88physical
28514442
C102A_HUMANCCDC102Aphysical
28514442
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of CCD91_HUMAN

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Related Literatures of Post-Translational Modification

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