C102A_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: C102A_HUMAN
• UniProt AC: Q96A19
• Protein Name: Coiled-coil domain-containing protein 102A
• Gene Name: CCDC102A
• Organism: Homo sapiens (Human).
• Sequence Length: 550
• Protein Sequence: MSHGPSPRLAESPQLSKGSLLTILGSPSPERMGPADSLPPTPPSGTPSPGPPPALPLPPAPALLADGDWESREELRLRELEEARARAAQMEKTMRRWSDCTANWREKWSKVRAERNRAREEVRQLRQRLDALTKELAGARRERQEAQGECEARGRELARLRGARGVADQTRDGPEPEAEREPVRDVGSERPPGSQELELVESLLKSMPEESEDCWEARSLGAGGPRGSSGRQERSRLPWEDTAATEEEASKLTALRLRLDESQKVLLKEREDKLALSRNIEKLEGELSQWKIKYEELSKTKQEMLKQLSILKEAHQDELGRMSEDLEDELGARSSMDRKMAELRGEMERLQAENAAEWGRRERLETEKLGLERENKKLRAQVGDLEEALARRRRQTASALDCDLRASQAALFEKNKELADLKHVHGKLKKQFQEKVAELAHANRRVEQHEAEVKKLRLRVEELKKELAQAEDELDEAHNQARKLQRSLDEQTEQSENLQVQLEHLQSRLRRQQQNAPLFGKIRSARFGTEEAEDGTSDLDEDEDLQIQVA

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
6	Phosphorylation	--MSHGPSPRLAESP --CCCCCCCCCCCCC	27.52	29514088
12	Phosphorylation	PSPRLAESPQLSKGS CCCCCCCCCCCCCCC	16.61	23401153
16	Phosphorylation	LAESPQLSKGSLLTI CCCCCCCCCCCEEHH	29.71	30266825
19	Phosphorylation	SPQLSKGSLLTILGS CCCCCCCCEEHHCCC	24.76	29255136
22	Phosphorylation	LSKGSLLTILGSPSP CCCCCEEHHCCCCCH	21.32	30266825
26	Phosphorylation	SLLTILGSPSPERMG CEEHHCCCCCHHHCC	20.82	30266825
28	Phosphorylation	LTILGSPSPERMGPA EHHCCCCCHHHCCCC	40.88	30266825
71	Phosphorylation	LADGDWESREELRLR CCCCCCCCHHHHHHH	40.51	22210691
101	Phosphorylation	MRRWSDCTANWREKW HHHHHHCCHHHHHHH	28.19	-
109	Phosphorylation	ANWREKWSKVRAERN HHHHHHHHHHHHHHH	32.13	-
188	Phosphorylation	EPVRDVGSERPPGSQ CCCCCCCCCCCCCHH	30.22	27080861
194	Phosphorylation	GSERPPGSQELELVE CCCCCCCHHHHHHHH	26.67	23663014
202	Phosphorylation	QELELVESLLKSMPE HHHHHHHHHHHCCCC	31.36	24719451
219	Phosphorylation	EDCWEARSLGAGGPR CCHHHHHHCCCCCCC	37.90	26657352
228	Phosphorylation	GAGGPRGSSGRQERS CCCCCCCCCCCCHHC	30.79	24719451
253	Phosphorylation	EEEASKLTALRLRLD HHHHHHHHHHHHHCC	27.64	24719451
277	Phosphorylation	REDKLALSRNIEKLE HHHHHHHHHCHHHHH	20.06	24719451
309	Phosphorylation	QEMLKQLSILKEAHQ HHHHHHHHHHHHHHH	24.31	24719451
396	Phosphorylation	LARRRRQTASALDCD HHHHHHHHHHHHCCH	22.29	28555341
464	Ubiquitination	RLRVEELKKELAQAE HHHHHHHHHHHHHHH	47.70	-
529	Phosphorylation	IRSARFGTEEAEDGT HHHHCCCCCCCCCCC	28.13	30278072
536	Phosphorylation	TEEAEDGTSDLDEDE CCCCCCCCCCCCCCC	31.24	28634120
537	Phosphorylation	EEAEDGTSDLDEDED CCCCCCCCCCCCCCC	41.53	29507054

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of C102A_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of C102A_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of C102A_HUMAN !!

Protein-Protein Interaction

Oops, there are no PPI records of C102A_HUMAN !!

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"A quantitative atlas of mitotic phosphorylation.";
Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.;
Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-26 AND SER-28, AND MASSSPECTROMETRY.
PubMed: 18669648