BZP63_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BZP63_ARATH
• UniProt AC: B9DGI8
• Protein Name: Basic leucine zipper 63
• Gene Name: BZIP63
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 314
• Subcellular Localization: Nucleus .
• Protein Description: Transcription factor..
• Protein Sequence: MEKVFSDEEISGNHHWSVNGMTSLNRSASEWAFNRFIQESSAAADDGESTTACGVSVSSPPNVPVDSEEYRAFLKSKLNLACAAVAMKRGTFIKPQDTSGRSDNGGANESEQASLASSKATPMMSSAITSGSELSGDEEEADGETNMNPTNVKRVKRMLSNRESARRSRRRKQAHLSELETQVSQLRVENSKLMKGLTDVTQTFNDASVENRVLKANIETLRAKVKMAEETVKRLTGFNPMFHNMPQIVSTVSLPSETSNSPDTTSSQVTTPEIISSGNKGKALIGCKMNRTASMRRVESLEHLQKRIRSVGDQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
27	Phosphorylation	GMTSLNRSASEWAFN CCCCCCHHHHHHHHH	34.76	25561503
29	Phosphorylation	TSLNRSASEWAFNRF CCCCHHHHHHHHHHH	34.61	19880383
59	Phosphorylation	ACGVSVSSPPNVPVD CCCCEECCCCCCCCC	42.07	19880383
102	Phosphorylation	PQDTSGRSDNGGANE CCCCCCCCCCCCCCH	38.66	19880383
160	Phosphorylation	KRVKRMLSNRESARR HHHHHHHHCHHHHHH	25.21	19880383
261	Phosphorylation	LPSETSNSPDTTSSQ CCCCCCCCCCCCCCC	24.74	19880383
294	Phosphorylation	CKMNRTASMRRVESL ECCCCCCHHHHHHHH	16.53	19880383
300	Phosphorylation	ASMRRVESLEHLQKR CHHHHHHHHHHHHHH	35.88	29348240

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
29	S	Phosphorylation	Kinase	KIN10	Q38997	Uniprot
294	S	Phosphorylation	Kinase	KIN10	Q38997	Uniprot
300	S	Phosphorylation	Kinase	KIN10	Q38997	Uniprot

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
29	S	Phosphorylation	The phosphorylation at Ser-29, Ser-294 and Ser-300 by KIN10 strongly enhances its ability to form homo- as well as heterodimers and are then essential for its transcriptional activity.	26263501
294	S	Phosphorylation	The phosphorylation at Ser-29, Ser-294 and Ser-300 by KIN10 strongly enhances its ability to form homo- as well as heterodimers and are then essential for its transcriptional activity.	26263501
300	S	Phosphorylation	The phosphorylation at Ser-29, Ser-294 and Ser-300 by KIN10 strongly enhances its ability to form homo- as well as heterodimers and are then essential for its transcriptional activity.	26263501

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BZP63_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
BZP63_ARATH	BZO2H3	physical	15469500
BZIP1_ARATH	bZIP1	physical	16709202
BZIP9_ARATH	BZIP9	physical	16709202
BZP10_ARATH	BZO2H1	physical	16709202

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.