BIM1_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BIM1_ARATH
• UniProt AC: Q9LEZ3
• Protein Name: Transcription factor BIM1
• Gene Name: BIM1
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 529
• Subcellular Localization: Nucleus .
• Protein Description: Positive brassinosteroid-signaling protein. Transcription factor that bind specifically to the DNA sequence 5'-CANNTG-3'(E box). Can bind individually to the promoter as a homodimer or synergistically as a heterodimer with BZR2/BES1. Does not itself activate transcription but enhances BZR2/BES1-mediated target gene activation..
• Protein Sequence: MELPQPRPFKTQGRKPTHDFLSLCSHSTVHPDPKPTPPPSSQGSHLKTHDFLQPLECVGAKEDVSRINSTTTASEKPPPPAPPPPLQHVLPGGIGTYTISPIPYFHHHHQRIPKPELSPPMMFNANERNVLDENSNSNCSSYAAASSGFTLWDESASGKKGQTRKENSVGERVNMRADVAATVGQWPVAERRSQSLTNNHMSGFSSLSSSQGSVLKSQSFMDMIRSAKGSSQEDDLDDEEDFIMKKESSSTSQSHRVDLRVKADVRGSPNDQKLNTPRSKHSATEQRRRSKINDRFQMLRQLIPNSDQKRDKASFLLEVIEYIQFLQEKADKYVTSYQGWNHEPAKLLNWQSNNNQQLVPEGVAFAPKLEEEKNNIPVSVLATAQGVVIDHPTTATTSPFPLSIQSNSFFSPVIAGNPVPQFHARVASSEAVEPSPSSRSQKEEEDEEVLEGNIRISSVYSQGLVKTLREALENSGVDLTKASISVEIELAKQSSSSSFKDHEVREPVSRTRNDNVKQTRKPKRLKTGQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
217	Phosphorylation	SQGSVLKSQSFMDMI CCCCHHHCHHHHHHH	27.22	25561503
219	Phosphorylation	GSVLKSQSFMDMIRS CCHHHCHHHHHHHHH	29.63	29654922
230	Phosphorylation	MIRSAKGSSQEDDLD HHHHCCCCCCCCCCC	28.30	25561503
231	Phosphorylation	IRSAKGSSQEDDLDD HHHCCCCCCCCCCCC	46.38	25561503
268	Phosphorylation	VKADVRGSPNDQKLN EEEECCCCCCCCCCC	15.23	25561503
428	Phosphorylation	QFHARVASSEAVEPS CCEEECCCCCCCCCC	26.34	30407730
429	Phosphorylation	FHARVASSEAVEPSP CEEECCCCCCCCCCC	21.60	30407730
435	Phosphorylation	SSEAVEPSPSSRSQK CCCCCCCCCCCCCCC	24.73	19880383
437	Phosphorylation	EAVEPSPSSRSQKEE CCCCCCCCCCCCCHH	42.60	19880383
438	Phosphorylation	AVEPSPSSRSQKEEE CCCCCCCCCCCCHHH	39.06	30407730
440	Phosphorylation	EPSPSSRSQKEEEDE CCCCCCCCCCHHHHH	47.77	30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BIM1_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BIM1_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BIM1_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
ESR1_ARATH	ESR1	physical	18830673
ESR2_ARATH	DRNL	physical	18830673
BZR2_ARATH	BES1	physical	15680330

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.