BAALC_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: BAALC_HUMAN
• UniProt AC: Q8WXS3
• Protein Name: Brain and acute leukemia cytoplasmic protein {ECO:0000303|PubMed:11707601}
• Gene Name: BAALC
• Organism: Homo sapiens (Human).
• Sequence Length: 180
• Subcellular Localization: Cytoplasm . Cell junction, synapse, synaptosome . Membrane raft . Cell junction, synapse, postsynaptic cell membrane, postsynaptic density . In neurons, localizes to postsynaptic lipid rafts (By similarity). In myocardial and skeletal muscle cells, l
• Protein Description: May play a synaptic role at the postsynaptic lipid rafts possibly through interaction with CAMK2A..
• Protein Sequence: MGCGGSRADAIEPRYYESWTRETESTWLTYTDSDAPPSAAAPDSGPEAGGLHSVLEAEKSKIKAPTDSVSDEGLFSASKMAPLAVFSHGMLEDGLPSNGVPRSTAPGGIPNPEKKTNCETQCPNPQSLSSGPLTQKQNGLQTTEAKRDAKRMPAKEVTINVTDSIQQMDRSRRITKNCVN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Myristoylation	------MGCGGSRAD ------CCCCCCHHH	20.83	-
3	S-palmitoylation	-----MGCGGSRADA -----CCCCCCHHHC	5.57	-
18	Phosphorylation	IEPRYYESWTRETES CCCCHHCCCCCCCCC	20.02	27732954
20	Phosphorylation	PRYYESWTRETESTW CCHHCCCCCCCCCEE	28.10	27732954
70	Phosphorylation	KAPTDSVSDEGLFSA CCCCCCCCCCCCCCH	33.62	27762562
158	Phosphorylation	RMPAKEVTINVTDSI HCCCCEEEEEEHHHH	14.13	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of BAALC_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of BAALC_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of BAALC_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
M3K1_HUMAN	MAP3K1	physical	26050649
KLF4_HUMAN	KLF4	physical	26050649
AT1B3_HUMAN	ATP1B3	physical	26050649
RING2_HUMAN	RNF2	physical	26050649
CHD1L_HUMAN	CHD1L	physical	26050649
CINP_HUMAN	CINP	physical	26050649
OSBL1_HUMAN	OSBPL1A	physical	26050649
AP1G1_HUMAN	AP1G1	physical	26050649

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.