B2L10_HUMAN - dbPTM
B2L10_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID B2L10_HUMAN
UniProt AC Q9HD36
Protein Name Bcl-2-like protein 10
Gene Name BCL2L10
Organism Homo sapiens (Human).
Sequence Length 194
Subcellular Localization Mitochondrion . Nucleus membrane .
Protein Description Promotes cell survival. Suppresses apoptosis induced by BAX but not BAK..
Protein Sequence MADPLRERTELLLADYLGYCAREPGTPEPAPSTPEAAVLRSAAARLRQIHRSFFSAYLGYPGNRFELVALMADSVLSDSPGPTWGRVVTLVTFAGTLLERGPLVTARWKKWGFQPRLKEQEGDVARDCQRLVALLSSRLMGQHRAWLQAQGGWDGFCHFFRTPFPLAFWRKQLVQAFLSCLLTTAFIYLWTRLL
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure
ASA (%) Reference Orthologous
Protein Cluster
92PhosphorylationGRVVTLVTFAGTLLE
HHHHHHHHHHHHHHH
15.75-
96PhosphorylationTLVTFAGTLLERGPL
HHHHHHHHHHHHCCC
25.41-
109UbiquitinationPLVTARWKKWGFQPR
CCEEHHHHHCCCCCC
32.8521890473
110UbiquitinationLVTARWKKWGFQPRL
CEEHHHHHCCCCCCH
45.6621890473
119UbiquitinationGFQPRLKEQEGDVAR
CCCCCHHCCCCCHHH
59.4621890473
120UbiquitinationFQPRLKEQEGDVARD
CCCCHHCCCCCHHHH
59.3921890473
136PhosphorylationQRLVALLSSRLMGQH
HHHHHHHHHHHHHHH
17.7924719451
137PhosphorylationRLVALLSSRLMGQHR
HHHHHHHHHHHHHHH
29.4224719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of B2L10_HUMAN !!

Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of B2L10_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10)
Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of B2L10_HUMAN !!

Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
B2L10_HUMANBCL2L10physical
11278245
BCL2_HUMANBCL2physical
11278245
BAX_HUMANBAXphysical
11278245
NR4A1_HUMANNR4A1physical
18835031

Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of B2L10_HUMAN

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Related Literatures of Post-Translational Modification

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