ATL55_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ATL55_ARATH
• UniProt AC: Q9LX93
• Protein Name: E3 ubiquitin-protein ligase RING1
• Gene Name: ATL55
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 301
• Subcellular Localization: Cell membrane ; Single-pass membrane protein .
• Protein Description: E3 ubiquitin-protein ligase that may be involved in positive regulation of programmed cell death (PCD) by facilitating degradation of negative regulators of PCD. May be involved in the early steps of the plant defense signaling pathway. Undergoes auto-ubiquitination..
• Protein Sequence: MAFNHRKMLLSCLQFKDLRFCFRQYPPPPPPPPPPRELSLLLPTSICVVGSIILFLFLVFFLYLHITQQRRISAASVTPGDTNQQEDEDETEERDFSDFHHVWQIPTVGLHRSAINSITVVGFKKGEGIIDGTECSVCLNEFEEDESLRLLPKCSHAFHLNCIDTWLLSHKNCPLCRAPVLLITEPPHQETETNHQPDSESSNDLRGRQDSSRSRRNHNIFLPRAQSDLANYCGSGRVENVRRSFSIGGSLSLCDGINNATRSGRQFYTSFSANLFSSSRRVRNEQPIPQNQMPSVTGNTS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
117	Phosphorylation	LHRSAINSITVVGFK CCHHHCCEEEEEEEE	17.33	28011693
119	Phosphorylation	RSAINSITVVGFKKG HHHCCEEEEEEEECC	14.68	28011693
227	Phosphorylation	IFLPRAQSDLANYCG CEECHHHHHHHHHCC	33.34	25561503

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
-	K	Ubiquitination	E3 ubiquitin ligase	ATL55	Q9LX93	PMID:22199232

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ATL55_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ATL55_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CLF_ARATH	CLF	physical	19097900
ATL55_ARATH	RING1	physical	19097900
LHP1_ARATH	TFL2	physical	19097900

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.