dbPTM

ATAD5_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ATAD5_HUMAN
UniProt AC	Q96QE3
Protein Name	ATPase family AAA domain-containing protein 5
Gene Name	ATAD5
Organism	Homo sapiens (Human).
Sequence Length	1844
Subcellular Localization	Nucleus .
Protein Description	Involved in DNA damage response. Involved in a RAD9A-related damage checkpoint, a pathway that is important in determining whether DNA damage is compatible with cell survival or whether it requires cell elimination by apoptosis. Modulates the RAD9A interaction with BCL2 and thereby induces DNA damages-induced apoptosis..
Protein Sequence	MVGVLAMAAAAAPPPVKDCEIEPCKKRKKDDDTSTCKTITKYLSPLGKTRDRVFAPPKPSNILDYFRKTSPTNEKTQLGKECKIKSPESVPVDSNKDCTTPLEMFSNVEFKKKRKRVNLSHQLNNIKTENEAPIEISSDDSKEDYSLNNDFVESSTSVLRYKKQVEVLAENIQDTKSQPNTMTSLQNSKKVNPKQGTTKNDFKKLRKRKCRDVVDLSESLPLAEELNLLKKDGKDTKQMENTTSHANSRDNVTEAAQLNDSIITVSYEEFLKSHKENKVEEIPDSTMSICVPSETVDEIVKSGYISESENSEISQQVRFKTVTVLAQVHPIPPKKTGKIPRIFLKQKQFEMENSLSDPENEQTVQKRKSNVVIQEEELELAVLEAGSSEAVKPKCTLEERQQFMKAFRQPASDALKNGVKKSSDKQKDLNEKCLYEVGRDDNSKKIMENSGIQMVSKNGNLQLHTDKGSFLKEKNKKLKKKNKKTLDTGAIPGKNREGNTQKKETTFFLKEKQYQNRMSLRQRKTEFFKSSTLFNNESLVYEDIANDDLLKVSSLCNNNKLSRKTSIPVKDIKLTQSKAESEASLLNVSTPKSTRRSGRISSTPTTETIRGIDSDDVQDNSQLKASTQKAANLSEKHSLYTAELITVPFDSESPIRMKFTRISTPKKSKKKSNKRSEKSEATDGGFTSQIRKASNTSKNISKAKQLIEKAKALHISRSKVTEEIAIPLRRSSRHQTLPERKKLSETEDSVIIIDSSPTALKHPEKNQKKLQCLNDVLGKKLNTSTKNVPGKMKVAPLFLVRKAQKAADPVPSFDESSQDTSEKSQDCDVQCKAKRDFLMSGLPDLLKRQIAKKAAALDVYNAVSTSFQRVVHVQQKDDGCCLWHLKPPSCPLLTKFKELNTKVIDLSKCGIALGEFSTLNSKLKSGNSAAVFMRTRKEFTEEVRNLLLEEIRWSNPEFSLKKYFPLLLKKQIEHQVLSSECHSKQELEADVSHKETKRKLVEAENSKSKRKKPNEYSKNLEKTNRKSEELSKRNNSSGIKLDSSKDSGTEDMLWTEKYQPQTASELIGNELAIKKLHSWLKDWKRRAELEERQNLKGKRDEKHEDFSGGIDFKGSSDDEEESRLCNTVLITGPTGVGKTAAVYACAQELGFKIFEVNASSQRSGRQILSQLKEATQSHQVDKQGVNSQKPCFFNSYYIGKSPKKISSPKKVVTSPRKVPPPSPKSSGPKRALPPKTLANYFKVSPKPKNNEEIGMLLENNKGIKNSFEQKQITQTKSTNATNSNVKDVGAEEPSRKNATSLILFEEVDVIFDEDAGFLNAIKTFMATTKRPVILTTSDPTFSLMFDGCFEEIKFSTPSLLNVASYLQMICLTENFRTDVKDFVTLLTANTCDIRKSILYLQFWIRSGGGVLEERPLTLYRGNSRNVQLVCSEHGLDNKIYPKNTKKKRVDLPKCDSGCAETLFGLKNIFSPSEDLFSFLKHKITMKEEWHKFIQLLTEFQMRNVDFLYSNLEFILPLPVDTIPETKNFCGPSVTVDASAATKSMNCLARKHSEREQPLKKSQKKKQKKTLVILDDSDLFDTDLDFPDQSISLSSVSSSSNAEESKTGDEESKARDKGNNPETKKSIPCPPKTTAGKKCSALVSHCLNSLSEFMDNMSFLDALLTDVREQNKYGRNDFSWTNGKVTSGLCDEFSLESNDGWTSQSSGELKAAAEALSFTKCSSAISKALETLNSCKKLGRDPTNDLTFYVSQKRNNVYFSQSAANLDNAWKRISVIKSVFSSRSLLYVGNRQASIIEYLPTLRNICKTEKLKEQGKSKRRFLHYFEGIHLDIPKETVNTLAADFP

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
38	Phosphorylation	DDTSTCKTITKYLSP CCCCHHHHHHHHHCC	35.71	-
42	Phosphorylation	TCKTITKYLSPLGKT HHHHHHHHHCCCCCC	12.08	30266825
44	Phosphorylation	KTITKYLSPLGKTRD HHHHHHHCCCCCCCC	18.26	30266825
48	Acetylation	KYLSPLGKTRDRVFA HHHCCCCCCCCCCCC	48.33	25953088
58	Acetylation	DRVFAPPKPSNILDY CCCCCCCCCCCHHHH	61.08	26051181
65	Phosphorylation	KPSNILDYFRKTSPT CCCCHHHHHHCCCCC	11.22	-
69	Phosphorylation	ILDYFRKTSPTNEKT HHHHHHCCCCCCCCC	35.36	28176443
70	Phosphorylation	LDYFRKTSPTNEKTQ HHHHHCCCCCCCCCC	32.53	26657352
72	Phosphorylation	YFRKTSPTNEKTQLG HHHCCCCCCCCCCCC	56.64	23312004
76	Phosphorylation	TSPTNEKTQLGKECK CCCCCCCCCCCCCCC	23.89	23312004
86	Phosphorylation	GKECKIKSPESVPVD CCCCCCCCCCCCCCC	37.06	30266825
89	Phosphorylation	CKIKSPESVPVDSNK CCCCCCCCCCCCCCC	34.80	30266825
94	Phosphorylation	PESVPVDSNKDCTTP CCCCCCCCCCCCCCC	46.11	29396449
99	Phosphorylation	VDSNKDCTTPLEMFS CCCCCCCCCCHHHHC	41.40	28961369
100	Phosphorylation	DSNKDCTTPLEMFSN CCCCCCCCCHHHHCC	32.01	28555341
106	Phosphorylation	TTPLEMFSNVEFKKK CCCHHHHCCCCHHHH	38.36	21712546
120	Phosphorylation	KRKRVNLSHQLNNIK HHHCCCHHHHHCCCC	12.18	28555341
127	Sumoylation	SHQLNNIKTENEAPI HHHHCCCCCCCCCCC	52.49	-
127	Sumoylation	SHQLNNIKTENEAPI HHHHCCCCCCCCCCC	52.49	28112733
127	Ubiquitination	SHQLNNIKTENEAPI HHHHCCCCCCCCCCC	52.49	29967540
137	Phosphorylation	NEAPIEISSDDSKED CCCCCCCCCCCCCCC	18.22	22777824
138	Phosphorylation	EAPIEISSDDSKEDY CCCCCCCCCCCCCCC	51.61	22777824
141	Phosphorylation	IEISSDDSKEDYSLN CCCCCCCCCCCCCCC	42.82	22777824
145	Phosphorylation	SDDSKEDYSLNNDFV CCCCCCCCCCCCHHH	19.02	25072903
146	Phosphorylation	DDSKEDYSLNNDFVE CCCCCCCCCCCHHHH	36.62	25072903
154	Phosphorylation	LNNDFVESSTSVLRY CCCHHHHCCHHHHHH	33.35	25072903
155	Phosphorylation	NNDFVESSTSVLRYK CCHHHHCCHHHHHHH	15.93	25072903
156	Phosphorylation	NDFVESSTSVLRYKK CHHHHCCHHHHHHHH	31.94	25072903
157	Phosphorylation	DFVESSTSVLRYKKQ HHHHCCHHHHHHHHH	22.54	25072903
170	Ubiquitination	KQVEVLAENIQDTKS HHHHHHHHHHHCCCC	51.18	24816145
175	Ubiquitination	LAENIQDTKSQPNTM HHHHHHCCCCCCCCC	19.07	24816145
177	Phosphorylation	ENIQDTKSQPNTMTS HHHHCCCCCCCCCHH	53.62	20068231
181	Phosphorylation	DTKSQPNTMTSLQNS CCCCCCCCCHHHCCC	28.63	20068231
183	Phosphorylation	KSQPNTMTSLQNSKK CCCCCCCHHHCCCCC	25.01	20068231
184	Phosphorylation	SQPNTMTSLQNSKKV CCCCCCHHHCCCCCC	19.69	20068231
188	Phosphorylation	TMTSLQNSKKVNPKQ CCHHHCCCCCCCCCC	22.38	20068231
217	Phosphorylation	CRDVVDLSESLPLAE CCCCCCHHHHCCHHH	22.22	23663014
219	Phosphorylation	DVVDLSESLPLAEEL CCCCHHHHCCHHHHH	31.73	30278072
230	Ubiquitination	AEELNLLKKDGKDTK HHHHHHHHHCCCCCH	52.57	29967540
249	Methylation	TTSHANSRDNVTEAA CCCHHHCCCCHHHHH	39.05	-
261	Phosphorylation	EAAQLNDSIITVSYE HHHHCCCCEEEEEHH	18.15	24532841
272	Ubiquitination	VSYEEFLKSHKENKV EEHHHHHHHCCCCCC	56.70	29967540
302	Phosphorylation	TVDEIVKSGYISESE HHHHHHHHCCCCCCC	26.40	30266825
304	Phosphorylation	DEIVKSGYISESENS HHHHHHCCCCCCCCC	14.36	30266825
306	Phosphorylation	IVKSGYISESENSEI HHHHCCCCCCCCCHH	26.96	23401153
308	Phosphorylation	KSGYISESENSEISQ HHCCCCCCCCCHHHH	34.97	30266825
311	Phosphorylation	YISESENSEISQQVR CCCCCCCCHHHHHHC	32.05	30266825
314	Phosphorylation	ESENSEISQQVRFKT CCCCCHHHHHHCEEE	15.54	29978859
354	Phosphorylation	KQFEMENSLSDPENE HHHCCCCCCCCCCCH	18.88	30266825
356	Phosphorylation	FEMENSLSDPENEQT HCCCCCCCCCCCHHH	51.44	30266825
363	Phosphorylation	SDPENEQTVQKRKSN CCCCCHHHHHHHHHC	20.80	28450419
369	Phosphorylation	QTVQKRKSNVVIQEE HHHHHHHHCCEECHH	38.60	18669648
405	Ubiquitination	EERQQFMKAFRQPAS HHHHHHHHHHHCHHH	45.74	29967540
432	Ubiquitination	KQKDLNEKCLYEVGR HHCCHHHHHHHHHCC	28.59	29967540
435	Phosphorylation	DLNEKCLYEVGRDDN CHHHHHHHHHCCCCC	20.31	27642862
443	Phosphorylation	EVGRDDNSKKIMENS HHCCCCCCCHHHHHC	42.17	-
450	Phosphorylation	SKKIMENSGIQMVSK CCHHHHHCCCEEEEC	24.78	28555341
467	Acetylation	NLQLHTDKGSFLKEK CEEEECCCCHHHHHH	58.57	23749302
469	Phosphorylation	QLHTDKGSFLKEKNK EEECCCCHHHHHHHH	32.90	24719451
484	Acetylation	KLKKKNKKTLDTGAI HHHHCCCCCCCCCCC	64.81	26210075
485	Phosphorylation	LKKKNKKTLDTGAIP HHHCCCCCCCCCCCC	31.32	28555341
494	Methylation	DTGAIPGKNREGNTQ CCCCCCCCCCCCCCC	47.69	-
494	Ubiquitination	DTGAIPGKNREGNTQ CCCCCCCCCCCCCCC	47.69	29967540
500	Phosphorylation	GKNREGNTQKKETTF CCCCCCCCCCEEEEE	53.26	22210691
510	Methylation	KETTFFLKEKQYQNR EEEEEECCHHHHHHH	58.68	-
510	Ubiquitination	KETTFFLKEKQYQNR EEEEEECCHHHHHHH	58.68	-
538	Phosphorylation	STLFNNESLVYEDIA CCCCCCCCCEEECCC	25.84	27067055
541	Phosphorylation	FNNESLVYEDIANDD CCCCCCEEECCCCCC	17.12	27642862
551	Ubiquitination	IANDDLLKVSSLCNN CCCCCHHHHHHHCCC	47.57	29967540
560	Acetylation	SSLCNNNKLSRKTSI HHHCCCCCCCCCCCC	50.38	26051181
560	Ubiquitination	SSLCNNNKLSRKTSI HHHCCCCCCCCCCCC	50.38	29967540
565	Phosphorylation	NNKLSRKTSIPVKDI CCCCCCCCCCCHHHC	30.67	22617229
566	Phosphorylation	NKLSRKTSIPVKDIK CCCCCCCCCCHHHCE	28.12	21406692
570	Acetylation	RKTSIPVKDIKLTQS CCCCCCHHHCEECCC	48.67	23749302
578	Sumoylation	DIKLTQSKAESEASL HCEECCCCHHHHHHH	46.48	-
578	Sumoylation	DIKLTQSKAESEASL HCEECCCCHHHHHHH	46.48	-
578	Ubiquitination	DIKLTQSKAESEASL HCEECCCCHHHHHHH	46.48	29967540
581	Phosphorylation	LTQSKAESEASLLNV ECCCCHHHHHHHCCC	43.24	23532336
589	Phosphorylation	EASLLNVSTPKSTRR HHHHCCCCCCCCCCC	37.61	29255136
590	Phosphorylation	ASLLNVSTPKSTRRS HHHCCCCCCCCCCCC	30.38	29255136
593	Phosphorylation	LNVSTPKSTRRSGRI CCCCCCCCCCCCCCC	28.49	21712546
594	Phosphorylation	NVSTPKSTRRSGRIS CCCCCCCCCCCCCCC	35.91	21712546
597	Phosphorylation	TPKSTRRSGRISSTP CCCCCCCCCCCCCCC	29.18	30576142
601	Phosphorylation	TRRSGRISSTPTTET CCCCCCCCCCCCCCC	27.14	29255136
602	Phosphorylation	RRSGRISSTPTTETI CCCCCCCCCCCCCCC	35.71	29255136
603	Phosphorylation	RSGRISSTPTTETIR CCCCCCCCCCCCCCC	20.19	29255136
605	Phosphorylation	GRISSTPTTETIRGI CCCCCCCCCCCCCCC	37.03	29255136
606	Phosphorylation	RISSTPTTETIRGID CCCCCCCCCCCCCCC	32.13	29255136
608	Phosphorylation	SSTPTTETIRGIDSD CCCCCCCCCCCCCCC	17.55	28450419
610	Ubiquitination	TPTTETIRGIDSDDV CCCCCCCCCCCCCCC	43.35	21963094
614	Phosphorylation	ETIRGIDSDDVQDNS CCCCCCCCCCCCCCH	33.51	25159151
615	Ubiquitination	TIRGIDSDDVQDNSQ CCCCCCCCCCCCCHH	57.25	22817900
621	Phosphorylation	SDDVQDNSQLKASTQ CCCCCCCHHHHHHHH	45.22	17525332
624	Ubiquitination	VQDNSQLKASTQKAA CCCCHHHHHHHHHHH	32.43	21963094
624 (in isoform 1)	Ubiquitination	-	32.43	21906983
624 (in isoform 2)	Ubiquitination	-	32.43	21906983
626	Phosphorylation	DNSQLKASTQKAANL CCHHHHHHHHHHHCH	29.77	22210691
627	Phosphorylation	NSQLKASTQKAANLS CHHHHHHHHHHHCHH	38.66	18669648
629	Ubiquitination	QLKASTQKAANLSEK HHHHHHHHHHCHHHH	49.94	22817900
638	Phosphorylation	ANLSEKHSLYTAELI HCHHHHCCCEEEEEE	33.85	25907765
640	Phosphorylation	LSEKHSLYTAELITV HHHHCCCEEEEEEEC	13.61	25907765
641	Phosphorylation	SEKHSLYTAELITVP HHHCCCEEEEEEECC	20.96	25907765
646	Phosphorylation	LYTAELITVPFDSES CEEEEEEECCCCCCC	34.45	22210691
651	Phosphorylation	LITVPFDSESPIRMK EEECCCCCCCCCEEE	40.11	25159151
653	Phosphorylation	TVPFDSESPIRMKFT ECCCCCCCCCEEEEE	29.58	25159151
660	Phosphorylation	SPIRMKFTRISTPKK CCCEEEEEECCCCCC	22.90	21406692
663	Phosphorylation	RMKFTRISTPKKSKK EEEEEECCCCCCCCC	35.05	20068231
664	Phosphorylation	MKFTRISTPKKSKKK EEEEECCCCCCCCCC	36.43	30576142
679	Phosphorylation	SNKRSEKSEATDGGF CCCCCCHHHCCCCCH	28.54	28555341
687	Phosphorylation	EATDGGFTSQIRKAS HCCCCCHHHHHHHHC	24.01	-
688	Phosphorylation	ATDGGFTSQIRKASN CCCCCHHHHHHHHCC	22.73	-
702	Acetylation	NTSKNISKAKQLIEK CCCCCHHHHHHHHHH	56.67	7714015
704	Acetylation	SKNISKAKQLIEKAK CCCHHHHHHHHHHHH	49.74	7714025
711	Acetylation	KQLIEKAKALHISRS HHHHHHHHHHCCCCC	63.65	7714035
721	Phosphorylation	HISRSKVTEEIAIPL CCCCCCCCCEECCCC	31.47	24719451
731	Phosphorylation	IAIPLRRSSRHQTLP ECCCCCCCCCCCCCC	25.86	24719451
732	Phosphorylation	AIPLRRSSRHQTLPE CCCCCCCCCCCCCCC	31.78	24719451
744	Phosphorylation	LPERKKLSETEDSVI CCCHHCCCCCCCCEE	51.88	23312004
746	Phosphorylation	ERKKLSETEDSVIII CHHCCCCCCCCEEEE	41.54	23312004
749	Phosphorylation	KLSETEDSVIIIDSS CCCCCCCCEEEECCC	14.69	23312004
755	Phosphorylation	DSVIIIDSSPTALKH CCEEEECCCCCHHCC	28.01	30266825
756	Phosphorylation	SVIIIDSSPTALKHP CEEEECCCCCHHCCH	23.63	19664994
758	Phosphorylation	IIIDSSPTALKHPEK EEECCCCCHHCCHHH	46.71	30266825
769	Sumoylation	HPEKNQKKLQCLNDV CHHHHHHHHHHHHHH	33.74	-
769	Sumoylation	HPEKNQKKLQCLNDV CHHHHHHHHHHHHHH	33.74	-
769	Ubiquitination	HPEKNQKKLQCLNDV CHHHHHHHHHHHHHH	33.74	29967540
779	Acetylation	CLNDVLGKKLNTSTK HHHHHHHHHCCCCCC	50.34	25953088
793	Sumoylation	KNVPGKMKVAPLFLV CCCCCCCCCCHHHHH	38.44	-
793	Sumoylation	KNVPGKMKVAPLFLV CCCCCCCCCCHHHHH	38.44	-
812	Phosphorylation	KAADPVPSFDESSQD HHCCCCCCCCCCCCC	45.63	23663014
816	Phosphorylation	PVPSFDESSQDTSEK CCCCCCCCCCCCCHH	34.83	23401153
817	Phosphorylation	VPSFDESSQDTSEKS CCCCCCCCCCCCHHH	29.99	23401153
820	Phosphorylation	FDESSQDTSEKSQDC CCCCCCCCCHHHCCC	31.02	30266825
821	Phosphorylation	DESSQDTSEKSQDCD CCCCCCCCHHHCCCC	51.85	30266825
824	Phosphorylation	SQDTSEKSQDCDVQC CCCCCHHHCCCCCHH	27.48	23312004
847	Ubiquitination	SGLPDLLKRQIAKKA CCCHHHHHHHHHHHH	49.94	-
860	Phosphorylation	KAAALDVYNAVSTSF HHHHHHHHHHHCCCC	9.32	24719451
865	Phosphorylation	DVYNAVSTSFQRVVH HHHHHHCCCCEEEEE	27.28	24719451
889	Phosphorylation	LWHLKPPSCPLLTKF EECCCCCCCCHHHHH	36.57	27499020
894	Phosphorylation	PPSCPLLTKFKELNT CCCCCHHHHHHHHCC	41.96	-
902	Ubiquitination	KFKELNTKVIDLSKC HHHHHCCEEEEHHHC	35.80	29967540
908	Ubiquitination	TKVIDLSKCGIALGE CEEEEHHHCCEECCC	43.72	29967540
922	Ubiquitination	EFSTLNSKLKSGNSA CHHHHHHHHCCCCCC	59.88	29967540
959	Phosphorylation	RWSNPEFSLKKYFPL CCCCCCCCHHHHHHH	37.30	24719451
970	Ubiquitination	YFPLLLKKQIEHQVL HHHHHHHHHHHHHHH	57.38	29967540
994	Ubiquitination	LEADVSHKETKRKLV HCCCCCHHHHHHHHH	60.62	24816145
996	Phosphorylation	ADVSHKETKRKLVEA CCCCHHHHHHHHHHH	40.74	26074081
999	Ubiquitination	SHKETKRKLVEAENS CHHHHHHHHHHHHHH	59.44	24816145
1006	Phosphorylation	KLVEAENSKSKRKKP HHHHHHHHHCCCCCC	29.79	26074081
1007	Ubiquitination	LVEAENSKSKRKKPN HHHHHHHHCCCCCCC	72.13	24816145
1008	Phosphorylation	VEAENSKSKRKKPNE HHHHHHHCCCCCCCH	37.20	26074081
1008	Ubiquitination	VEAENSKSKRKKPNE HHHHHHHCCCCCCCH	37.20	24816145
1012	Ubiquitination	NSKSKRKKPNEYSKN HHHCCCCCCCHHHHH	58.05	24816145
1013	Ubiquitination	SKSKRKKPNEYSKNL HHCCCCCCCHHHHHH	41.75	24816145
1016	Phosphorylation	KRKKPNEYSKNLEKT CCCCCCHHHHHHHHH	31.42	26074081
1017	Phosphorylation	RKKPNEYSKNLEKTN CCCCCHHHHHHHHHH	14.64	26074081
1040	Ubiquitination	RNNSSGIKLDSSKDS HCCCCCCCCCCCCCC	50.17	29967540
1058	Phosphorylation	DMLWTEKYQPQTASE CCCEEECCCCCCHHH	21.13	-
1074	Ubiquitination	IGNELAIKKLHSWLK HCCHHHHHHHHHHHH	43.61	29967540
1075	Ubiquitination	GNELAIKKLHSWLKD CCHHHHHHHHHHHHH	45.37	29967540
1107	Phosphorylation	DEKHEDFSGGIDFKG CCCCCCCCCCCCCCC	48.72	30576142
1115	Phosphorylation	GGIDFKGSSDDEEES CCCCCCCCCCHHHHH	31.05	25159151
1116	Phosphorylation	GIDFKGSSDDEEESR CCCCCCCCCHHHHHH	58.72	25159151
1122	Phosphorylation	SSDDEEESRLCNTVL CCCHHHHHHHCCEEE	33.56	30576142
1152	Acetylation	CAQELGFKIFEVNAS HHHHHCCEEEEECCC	44.69	20167786
1169	Phosphorylation	RSGRQILSQLKEATQ HHHHHHHHHHHHHHH	34.79	24719451
1172	Ubiquitination	RQILSQLKEATQSHQ HHHHHHHHHHHHHCC	37.35	29967540
1175	Phosphorylation	LSQLKEATQSHQVDK HHHHHHHHHHCCCCC	31.53	23312004
1177	Phosphorylation	QLKEATQSHQVDKQG HHHHHHHHCCCCCCC	16.13	23312004
1182	Ubiquitination	TQSHQVDKQGVNSQK HHHCCCCCCCCCCCC	50.52	29967540
1187	Phosphorylation	VDKQGVNSQKPCFFN CCCCCCCCCCCCEEE	36.86	23312004
1195	Phosphorylation	QKPCFFNSYYIGKSP CCCCEEECEECCCCC	17.73	23312004
1196	Phosphorylation	KPCFFNSYYIGKSPK CCCEEECEECCCCCC	10.54	23312004
1197	Phosphorylation	PCFFNSYYIGKSPKK CCEEECEECCCCCCC	11.74	23312004
1201	Phosphorylation	NSYYIGKSPKKISSP ECEECCCCCCCCCCC	36.42	23401153
1206	Phosphorylation	GKSPKKISSPKKVVT CCCCCCCCCCCCEEC	49.85	20068231
1207	Phosphorylation	KSPKKISSPKKVVTS CCCCCCCCCCCEECC	44.18	17929957
1213	Phosphorylation	SSPKKVVTSPRKVPP CCCCCEECCCCCCCC	35.68	30266825
1214	O-linked_Glycosylation	SPKKVVTSPRKVPPP CCCCEECCCCCCCCC	15.88	30379171
1214	Phosphorylation	SPKKVVTSPRKVPPP CCCCEECCCCCCCCC	15.88	30266825
1222	Phosphorylation	PRKVPPPSPKSSGPK CCCCCCCCCCCCCCC	51.22	30266825
1225	Phosphorylation	VPPPSPKSSGPKRAL CCCCCCCCCCCCCCC	43.86	23312004
1226	Phosphorylation	PPPSPKSSGPKRALP CCCCCCCCCCCCCCC	66.30	23312004
1236	Phosphorylation	KRALPPKTLANYFKV CCCCCCHHHHHHCCC	36.56	26074081
1240	Phosphorylation	PPKTLANYFKVSPKP CCHHHHHHCCCCCCC	10.12	30576142
1244	Phosphorylation	LANYFKVSPKPKNNE HHHHCCCCCCCCCCH	28.00	25159151
1264	Ubiquitination	LENNKGIKNSFEQKQ HHCCCCCCCCHHHHC	56.03	29967540
1270	Ubiquitination	IKNSFEQKQITQTKS CCCCHHHHCCCCCCC	36.15	29967540
1276	Ubiquitination	QKQITQTKSTNATNS HHCCCCCCCCCCCCC	45.53	29967540
1286	Ubiquitination	NATNSNVKDVGAEEP CCCCCCCCCCCCCCC	51.45	29967540
1294	Phosphorylation	DVGAEEPSRKNATSL CCCCCCCCCCCCCEE	60.20	-
1323	Phosphorylation	GFLNAIKTFMATTKR CHHHHHHHHHHCCCC	16.72	29116813
1327	Phosphorylation	AIKTFMATTKRPVIL HHHHHHHCCCCCEEE	22.51	29116813
1337	Phosphorylation	RPVILTTSDPTFSLM CCEEEECCCCCEEHH	36.04	29116813
1342	Phosphorylation	TTSDPTFSLMFDGCF ECCCCCEEHHCCCCC	22.77	29116813
1384	Phosphorylation	TDVKDFVTLLTANTC CCHHHHHHHHHCCCC	18.95	29449344
1387	Phosphorylation	KDFVTLLTANTCDIR HHHHHHHHCCCCCHH	22.45	29449344
1390	Phosphorylation	VTLLTANTCDIRKSI HHHHHCCCCCHHHHH	14.75	29449344
1477	Phosphorylation	SPSEDLFSFLKHKIT CCCHHHHHHHHHCCC	36.65	24719451
1552	Phosphorylation	NCLARKHSEREQPLK HHHHHHCCCCCCCCC	41.19	24719451
1664	Phosphorylation	SFLDALLTDVREQNK HHHHHHHHHHHHHHC	33.04	18452278
1716	Phosphorylation	KAAAEALSFTKCSSA HHHHHHHHHHHHHHH	37.61	24719451
1718	Phosphorylation	AAEALSFTKCSSAIS HHHHHHHHHHHHHHH	27.97	-
1752	Ubiquitination	LTFYVSQKRNNVYFS CEEEEEECCCCEEEC	49.97	29967540
1770	Ubiquitination	ANLDNAWKRISVIKS HCCHHHHHHHHHHHH	37.13	-
1780	Phosphorylation	SVIKSVFSSRSLLYV HHHHHHHCCCCEEEE	23.76	30278072
1781	Phosphorylation	VIKSVFSSRSLLYVG HHHHHHCCCCEEEEC	17.90	30278072
1783	Phosphorylation	KSVFSSRSLLYVGNR HHHHCCCCEEEECCC	25.36	30278072
1823	Phosphorylation	SKRRFLHYFEGIHLD CHHHHHHHHCCCCCC	12.89	23898821

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
653	S	Phosphorylation	Kinase	CDK1	P06493	PSP

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ATAD5_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ATAD5_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
WDR48_HUMAN	WDR48	physical	20147293
RFC4_HUMAN	RFC4	physical	20147293
BRD4_HUMAN	BRD4	physical	21555454
CPVL_HUMAN	CPVL	physical	21555454
BAZ1B_HUMAN	BAZ1B	physical	21555454
UBP1_HUMAN	USP1	physical	21555454

Drug and Disease Associations

Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ATAD5_HUMAN

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Quantitative phosphoproteomic analysis of T cell receptor signalingreveals system-wide modulation of protein-protein interactions."; Mayya V., Lundgren D.H., Hwang S.-I., Rezaul K., Wu L., Eng J.K.,Rodionov V., Han D.K.; Sci. Signal. 2:RA46-RA46(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-306; SER-311; SER-614AND SER-817, AND MASS SPECTROMETRY.	19690332 [Abstract]
"A quantitative atlas of mitotic phosphorylation."; Dephoure N., Zhou C., Villen J., Beausoleil S.A., Bakalarski C.E.,Elledge S.J., Gygi S.P.; Proc. Natl. Acad. Sci. U.S.A. 105:10762-10767(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-44; SER-306; SER-369;SER-1115 AND SER-1116, AND MASS SPECTROMETRY.	18669648 [Abstract]
"Combining protein-based IMAC, peptide-based IMAC, and MudPIT forefficient phosphoproteomic analysis."; Cantin G.T., Yi W., Lu B., Park S.K., Xu T., Lee J.-D.,Yates J.R. III; J. Proteome Res. 7:1346-1351(2008). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-653, AND MASSSPECTROMETRY.	18220336 [Abstract]
"ATM and ATR substrate analysis reveals extensive protein networksresponsive to DNA damage."; Matsuoka S., Ballif B.A., Smogorzewska A., McDonald E.R. III,Hurov K.E., Luo J., Bakalarski C.E., Zhao Z., Solimini N.,Lerenthal Y., Shiloh Y., Gygi S.P., Elledge S.J.; Science 316:1160-1166(2007). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-621, AND MASSSPECTROMETRY.	17525332 [Abstract]
"Global, in vivo, and site-specific phosphorylation dynamics insignaling networks."; Olsen J.V., Blagoev B., Gnad F., Macek B., Kumar C., Mortensen P.,Mann M.; Cell 127:635-648(2006). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-663 AND THR-664, ANDMASS SPECTROMETRY.	17081983 [Abstract]