| UniProt ID | ACA12_ARATH | |
|---|---|---|
| UniProt AC | Q9LY77 | |
| Protein Name | Calcium-transporting ATPase 12, plasma membrane-type | |
| Gene Name | ACA12 | |
| Organism | Arabidopsis thaliana (Mouse-ear cress). | |
| Sequence Length | 1033 | |
| Subcellular Localization |
Membrane Multi-pass membrane protein. |
|
| Protein Description | This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the translocation of calcium from the cytosol out of the cell or into organelles.. | |
| Protein Sequence | MRDLKEYDYSALLLNLTTSSLNKAQRRWRFAYAAIYSMRAMLSLVKEIVPARIDPKTSDASLSLSYTALESGEGAKINSMPLSYVPAIDQEQLVEIMKGKDLPGIQALGGVEGVAASLRTNPTKGIHGNEQEVSRRRDLFGSNTYHKPPPKGLLFFVYEAFKDLTILILLVCAIFSLGFGIKEHGIKEGWYEGGSIFVAVFLVIVVSALSNFRQERQFDKLSKISNNIKVEVLRDSRRQHISIFDVVVGDVVFLKIGDQIPADGLFLEGHSLQVDESSMTGESDHLEVDHKDNPFLFSGTKIVDGFAQMLVVSVGMSTTWGQTMSSINQDSSERTPLQVRLDTLTSTIGKIGLTVAALVLVVLLVRYFTGNTEKEGKREYNGSKTPVDTVVNSVVRIVAAAVTIVVVAIPEGLPLAVTLTLAYSMKRMMSDQAMVRKLSACETMGSATVICTDKTGTLTLNEMKVTKFWLGQESIHEDSTKMISPDVLDLLYQGTGLNTTGSVCVSDSGSTPEFSGSPTEKALLSWTVLNLGMDMESVKQKHEVLRVETFSSAKKRSGVLVRRKSDNTVHVHWKGAAEMVLAMCSHYYTSTGSVDLMDSTAKSRIQAIIQGMAASSLRCIAFAHKIASNDSVLEEDGLTLMGIVGLKDPCRPGVSKAVETCKLAGVTIKMITGDNVFTAKAIAFECGILDHNDKDEEDAVVEGVQFRNYTDEERMQKVDKIRVMARSSPSDKLLMVKCLRLKGHVVAVTGDGTNDAPALKEADIGLSMGIQGTEVAKESSDIVILDDNFASVATVLKWGRCVYNNIQKFIQFQLTVNVAALVINFIAAISAGEVPLTAVQLLWVNLIMDTLGALALATERPTNELLKRKPVGRTEALITNVMWRNLLVQSLYQIAVLLILQFKGMSIFSVRKEVKDTLIFNTFVLCQVFNEFNAREMEKKNVFKGLHRNRLFIGIIAITIVLQVIMVEFLKKFADTVRLNGWQWGTCIALASLSWPIGFFTKFIPVSETPFLSYFKNPRSLFKGSRSPSLKKP | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 1 | Acetylation | -------MRDLKEYD -------CCCHHHCC | 34.87 | - | |
| 37 | Phosphorylation | FAYAAIYSMRAMLSL HHHHHHHHHHHHHHH | 8.83 | - | |
| 271 | Phosphorylation | GLFLEGHSLQVDESS CEEEECEEEEECCCC | 31.21 | 28011693 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ACA12_ARATH !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ACA12_ARATH !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ACA12_ARATH !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| HHP2_ARATH | HHP2 | physical | 24833385 | |
| HHP4_ARATH | HHP4 | physical | 24833385 | |
| UBC32_ARATH | UBC32 | physical | 24833385 | |
| UBC34_ARATH | UBC34 | physical | 24833385 | |
| TRXH3_ARATH | TRX3 | physical | 24833385 | |
| CNIH1_ARATH | AT3G12180 | physical | 24833385 | |
| CP21D_ARATH | AT3G66654 | physical | 24833385 | |
| BET12_ARATH | ATBET12 | physical | 24833385 | |
| TBL18_ARATH | TBL18 | physical | 24833385 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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