dbPTM

ZSC16_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	ZSC16_HUMAN
UniProt AC	Q9H4T2
Protein Name	Zinc finger and SCAN domain-containing protein 16
Gene Name	ZSCAN16
Organism	Homo sapiens (Human).
Sequence Length	348
Subcellular Localization	Nucleus .
Protein Description	May be involved in transcriptional regulation..
Protein Sequence	MTTALEPEDQKGLLIIKAEDHYWGQDSSSQKCSPHRRELYRQHFRKLCYQDAPGPREALTQLWELCRQWLRPECHTKEQILDLLVLEQFLSILPKDLQAWVRAHHPETGEEAVTVLEDLERELDEPGKQVPGNSERRDILMDKLAPLGRPYESLTVQLHPKKTQLEQEAGKPQRNGDKTRTKNEELFQKEDMPKDKEFLGEINDRLNKDTPQHPKSKDIIENEGRSEWQQRERRRYKCDECGKSFSHSSDLSKHRRTHTGEKPYKCDECGKAFIQRSHLIGHHRVHTGVKPYKCKECGKDFSGRTGLIQHQRIHTGEKPYECDECGRPFRVSSALIRHQRIHTANKLY

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
128	Ubiquitination	RELDEPGKQVPGNSE HHHCCCCCCCCCCHH	59.86	-
210	Phosphorylation	NDRLNKDTPQHPKSK HHHHCCCCCCCCCCH	26.85	24719451
257	Phosphorylation	DLSKHRRTHTGEKPY HHHHCCCCCCCCCCC	24.60	28348404
259	Phosphorylation	SKHRRTHTGEKPYKC HHCCCCCCCCCCCCC	46.56	26270265
262	Ubiquitination	RRTHTGEKPYKCDEC CCCCCCCCCCCCCHH	55.80	-
277	Phosphorylation	GKAFIQRSHLIGHHR HHHHHHHHHHHCCCC	13.28	27174698
302	Phosphorylation	KECGKDFSGRTGLIQ CCCCCCCCCCCCCEE	37.18	22210691
305	Phosphorylation	GKDFSGRTGLIQHQR CCCCCCCCCCEECCE	39.61	22210691
315	Phosphorylation	IQHQRIHTGEKPYEC EECCEECCCCCCCCC	44.67	28111955

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of ZSC16_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of ZSC16_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of ZSC16_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
S2538_HUMAN	SLC25A38	physical	16169070
A4_HUMAN	APP	physical	21832049

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of ZSC16_HUMAN

Related Literatures of Post-Translational Modification