| UniProt ID | ZNT2_HUMAN | |
|---|---|---|
| UniProt AC | Q9BRI3 | |
| Protein Name | Zinc transporter 2 | |
| Gene Name | SLC30A2 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 323 | |
| Subcellular Localization |
Vacuole membrane Multi-pass membrane protein . Isoform 2: Lysosome membrane. |
|
| Protein Description | ||
| Protein Sequence | MEAKEKQHLLDARPAIRSYTGSLWQEGAGWIPLPRPGLDLQAIELAAQSNHHCHAQKGPDSHCDPKKGKAQRQLYVASAICLLFMIGEVVEILGALVSVLSIWVVTGVLVYLAVERLISGDYEIDGGTMLITSGCAVAVNIIMGLTLHQSGHGHSHGTTNQQEENPSVRAAFIHVIGDFMQSMGVLVAAYILYFKPEYKYVDPICTFVFSILVLGTTLTILRDVILVLMEGTPKGVDFTAVRDLLLSVEGVEALHSLHIWALTVAQPVLSVHIAIAQNTDAQAVLKTASSRLQGKFHFHTVTIQIEDYSEDMKDCQACQGPSD | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
|
|
||
* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 4 | Ubiquitination | ----MEAKEKQHLLD ----CCHHHHHHHHH | 52.73 | - | |
| 6 | Ubiquitination | --MEAKEKQHLLDAR --CCHHHHHHHHHHH | 42.16 | - | |
| 131 (in isoform 2) | Phosphorylation | - | 1.68 | - | |
| 239 | Phosphorylation | TPKGVDFTAVRDLLL CCCCCCHHHHHHHHH | 21.56 | - | |
| 247 | Phosphorylation | AVRDLLLSVEGVEAL HHHHHHHCHHHHHHH | 20.35 | - | |
| 296 (in isoform 2) | Phosphorylation | - | 10.73 | - | |
| 300 | Phosphorylation | QGKFHFHTVTIQIED CCEEEEEEEEEEEEC | 20.57 | 27251275 | |
| 302 | Phosphorylation | KFHFHTVTIQIEDYS EEEEEEEEEEEECCC | 14.33 | 27251275 | |
| 349 (in isoform 2) | Phosphorylation | - | 27251275 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of ZNT2_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of ZNT2_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of ZNT2_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| CC4L_HUMAN | CCL4L2 | physical | 25416956 | |
| TNR12_HUMAN | TNFRSF12A | physical | 25416956 | |
| ADA33_HUMAN | ADAM33 | physical | 25416956 | |
| KASH5_HUMAN | CCDC155 | physical | 25416956 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
loading...
