ZN567_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN567_HUMAN
• UniProt AC: Q8N184
• Protein Name: Zinc finger protein 567
• Gene Name: ZNF567
• Organism: Homo sapiens (Human).
• Sequence Length: 647
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MAQGSVSFNDVTVDFTQEEWQHLDHAQKTLYMDVMLENYCHLISVGCHMTKPDVILKLERGEEPWTSFAGHTCLEENWKAEDFLVKFKEHQEKYSRSVVSINHKKLVKEKSKIYEKTFTLGKNPVNSKNLPPEYDTHGRILKNVSELIISNLNPARKRLSEYNGYGKSLLSTKQETTHPEVKSHNQSARAFSHNEVLMQYQKTETPAQSFGYNDCEKSFLQRGGLITHSRPYKGENPSVYNKKRRATNIEKKHTCNECGKSFCRKSVLILHQGIHSEEKPYQCHQCGNAFRRKSYLIDHQRTHTGEKPFVCNECGKSFRLKTALTDHQRTHTGEKSYECLQCRNAFRLKSHLIRHQRTHTGEKPYECNDCGKSFRQKTTLSLHQRIHTGEKPYICKECGKSFHQKANLTVHQRTHTGEKPYICNECGKSFSQKTTLALHEKTHNEEKPYICSECGKSFRQKTTLVAHQRTHTGEKSYECPHCGKAFRMKSYLIDHHRTHTGEKPYECNECGKSFSQKTNLNLHQRIHTGEKPYVCNECGKSFRQKATLTVHQKIHTGQKSYECPQCGKAFSRKSYLIHHQRTHTGEKPYKCSECGKCFRQKTNLIVHQRTHTGEKPYVCNECGKSFSYKRNLIVHQRTHKGENIEMQ

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
26 (in isoform 1)	Ubiquitination	-	16.54	21890473
39	Phosphorylation	MDVMLENYCHLISVG HHHHHHHHHEEEEEE	3.34	24043423
44	Phosphorylation	ENYCHLISVGCHMTK HHHHEEEEEECCCCC	20.86	24043423
50	Phosphorylation	ISVGCHMTKPDVILK EEEECCCCCCCEEEE	18.76	24043423
55 (in isoform 1)	Ubiquitination	-	3.51	21890473
57	Ubiquitination	TKPDVILKLERGEEP CCCCEEEEEECCCCC	36.86	21890473
57 (in isoform 3)	Ubiquitination	-	36.86	21890473
57 (in isoform 2)	Ubiquitination	-	36.86	21890473
86	Ubiquitination	KAEDFLVKFKEHQEK CHHHHHHHHHHHHHH	53.52	21890473
86 (in isoform 3)	Ubiquitination	-	53.52	21890473
86 (in isoform 2)	Ubiquitination	-	53.52	21890473
100	O-linked_Glycosylation	KYSRSVVSINHKKLV HHCCCEEECCHHHHH	18.60	30379171
145	Phosphorylation	GRILKNVSELIISNL HHHHHCHHHHHHHCC	35.76	30622161
160	Phosphorylation	NPARKRLSEYNGYGK CHHHHHHHHHCCCCH	41.91	28555341
162	Phosphorylation	ARKRLSEYNGYGKSL HHHHHHHHCCCCHHH	15.54	28555341
171	Phosphorylation	GYGKSLLSTKQETTH CCCHHHHCCCCCCCC	38.56	24719451
173	Sumoylation	GKSLLSTKQETTHPE CHHHHCCCCCCCCHH	42.64	-
173	Sumoylation	GKSLLSTKQETTHPE CHHHHCCCCCCCCHH	42.64	28112733
202	Sumoylation	EVLMQYQKTETPAQS HHHHHHHCCCCCCHH	43.31	28112733
217	Sumoylation	FGYNDCEKSFLQRGG CCCCHHHHHHHHCCC	53.49	28112733
233	Sumoylation	ITHSRPYKGENPSVY ECCCCCCCCCCCHHH	63.53	28112733
238	Phosphorylation	PYKGENPSVYNKKRR CCCCCCCHHHCHHCC	49.14	26074081
240	Phosphorylation	KGENPSVYNKKRRAT CCCCCHHHCHHCCCC	26.12	26074081
247	Phosphorylation	YNKKRRATNIEKKHT HCHHCCCCCCCCCCC	34.61	26074081
254	Phosphorylation	TNIEKKHTCNECGKS CCCCCCCCCCHHCHH	26.38	26074081
302	Phosphorylation	YLIDHQRTHTGEKPF EECCCCCCCCCCCCE	19.74	-
304	Phosphorylation	IDHQRTHTGEKPFVC CCCCCCCCCCCCEEE	46.56	-
330	Phosphorylation	ALTDHQRTHTGEKSY ECCCCCCCCCCCCCC	19.74	-
332	Phosphorylation	TDHQRTHTGEKSYEC CCCCCCCCCCCCCHH	46.56	-
358	Phosphorylation	HLIRHQRTHTGEKPY HHHHCCCCCCCCCCE	19.74	-
360	Phosphorylation	IRHQRTHTGEKPYEC HHCCCCCCCCCCEEC	46.56	-
388	Phosphorylation	SLHQRIHTGEKPYIC EHHHHHHCCCCCEEE	44.67	28111955
401	Phosphorylation	ICKECGKSFHQKANL EECCCCCCHHHHCCC	17.16	-
414	Phosphorylation	NLTVHQRTHTGEKPY CCEEEECCCCCCCCE	19.74	-
416	Phosphorylation	TVHQRTHTGEKPYIC EEEECCCCCCCCEEE	46.56	21712546
447	Sumoylation	EKTHNEEKPYICSEC HHHCCCCCCEEECCC	36.62	28112733
447	Sumoylation	EKTHNEEKPYICSEC HHHCCCCCCEEECCC	36.62	-
452	Phosphorylation	EEKPYICSECGKSFR CCCCEEECCCCCCHH	26.77	-
457	Phosphorylation	ICSECGKSFRQKTTL EECCCCCCHHHCCEE	15.79	-
461	Sumoylation	CGKSFRQKTTLVAHQ CCCCHHHCCEEEEEC	38.94	-
462	Phosphorylation	GKSFRQKTTLVAHQR CCCHHHCCEEEEECC	19.61	-
470	Phosphorylation	TLVAHQRTHTGEKSY EEEEECCCCCCCCCE	19.74	-
472	Phosphorylation	VAHQRTHTGEKSYEC EEECCCCCCCCCEEC	46.56	-
491	Phosphorylation	KAFRMKSYLIDHHRT CEEEEHHHHCCCCCC	11.36	18083107
498	Phosphorylation	YLIDHHRTHTGEKPY HHCCCCCCCCCCCCE	21.31	28348404
500	Phosphorylation	IDHHRTHTGEKPYEC CCCCCCCCCCCCEEC	46.56	29496963
503	Ubiquitination	HRTHTGEKPYECNEC CCCCCCCCCEECCCC	55.00	-
517	Sumoylation	CGKSFSQKTNLNLHQ CCCCCCCCCCCCHHH	37.88	-
528	Phosphorylation	NLHQRIHTGEKPYVC CHHHHHCCCCCCEEE	44.67	28111955
556	Phosphorylation	TVHQKIHTGQKSYEC EEEHHHHCCCCCEEC	44.79	-
582	Phosphorylation	YLIHHQRTHTGEKPY EEEEECCCCCCCCCE	19.74	28348404
584	Phosphorylation	IHHQRTHTGEKPYKC EEECCCCCCCCCEEC	46.56	26270265
589	Phosphorylation	THTGEKPYKCSECGK CCCCCCCEECCCCCH	35.38	-
592	Phosphorylation	GEKPYKCSECGKCFR CCCCEECCCCCHHHH	31.59	-
610	Phosphorylation	NLIVHQRTHTGEKPY CEEEEECCCCCCCCE	19.74	-
612	Phosphorylation	IVHQRTHTGEKPYVC EEEECCCCCCCCEEE	46.56	-
617	Phosphorylation	THTGEKPYVCNECGK CCCCCCCEEECCCCC	28.80	-
625	Phosphorylation	VCNECGKSFSYKRNL EECCCCCCEECCCCE	12.52	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN567_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN567_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN567_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
FAM9B_HUMAN	FAM9B	physical	25416956
M3K20_HUMAN	ZAK	physical	21516116

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.