ZN559_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN559_HUMAN
• UniProt AC: Q9BR84
• Protein Name: Zinc finger protein 559
• Gene Name: ZNF559
• Organism: Homo sapiens (Human).
• Sequence Length: 538
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MVAGWLTNYSQDSVTFEDVAVDFTQEEWTLLDQTQRNLYRDVMLENYKNLVAVDWESHINTKWSAPQQNFLQGKTSSVVEMERNHFGEELFDFNQCEKALSEHSCLKTHRRTYFRKKTCECNQCEKAFRKPSIFTLHKKTDIGEELPNCNQCETAFSQHLHLVCKKTSQNLHLVCKKTHTQEKPYKCSDCEKGLPSSSHLRECVRIYGGERPYTHKEYVETFSHSTALFVHMQTQDGEKFYECKACGKPFTESSYLTQHLRTHSRVLPIEHKKFGKAFAFSPDLAKHIRLRTRGKHYVCNECGKEFTCFSKLNIHIRVHTGEKPYECNKCGKAFTDSSGLIKHRRTHTGEKPYECKECGKAFANSSHLTVHMRTHTGEKPYQCKECGKAFINSSSFKSHMQTHPGVKPYDCQQCGKAFIRSSFLIRHLRSHSAERPFECEECGKAFRYSSHLSQHKRIHTGERPYKCQKCGQAFSISSGLTVHMRTHTGERPFECQECGKAFTRSTYLIRHLRSHSVEKPYKECGQTFSNSSCLTECV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
132	Phosphorylation	EKAFRKPSIFTLHKK HHHHCCCCEEEEEEC	33.11	29083192
135	Phosphorylation	FRKPSIFTLHKKTDI HCCCCEEEEEECCCC	26.70	29083192
281	Phosphorylation	FGKAFAFSPDLAKHI CCCEEECCHHHHHHH	17.67	28555341
286	Ubiquitination	AFSPDLAKHIRLRTR ECCHHHHHHHHHHCC	47.03	-
320	Phosphorylation	NIHIRVHTGEKPYEC EEEEEEECCCCCCCC	44.15	-
346	Phosphorylation	GLIKHRRTHTGEKPY CCCCCCCCCCCCCCE	24.60	29396449
348	Phosphorylation	IKHRRTHTGEKPYEC CCCCCCCCCCCCEEC	46.56	29496963
351	Ubiquitination	RRTHTGEKPYECKEC CCCCCCCCCEECCHH	55.00	-
356	Sumoylation	GEKPYECKECGKAFA CCCCEECCHHHHEEE	44.06	-
356	Ubiquitination	GEKPYECKECGKAFA CCCCEECCHHHHEEE	44.06	-
356	Sumoylation	GEKPYECKECGKAFA CCCCEECCHHHHEEE	44.06	-
374	Phosphorylation	HLTVHMRTHTGEKPY CEEEEEECCCCCCCE	19.06	-
376	Phosphorylation	TVHMRTHTGEKPYQC EEEEECCCCCCCEEC	46.56	-
398	Phosphorylation	INSSSFKSHMQTHPG ECCHHHHHHHCCCCC	23.37	24719451
416	Ubiquitination	YDCQQCGKAFIRSSF CCHHHHHHHHHHHHH	47.99	-
448	Phosphorylation	ECGKAFRYSSHLSQH HHHHHHHHHHHHHCC	14.20	27273156
449	Phosphorylation	CGKAFRYSSHLSQHK HHHHHHHHHHHHCCC	13.66	27273156
460	Phosphorylation	SQHKRIHTGERPYKC HCCCCCCCCCCCCCC	38.06	27273156
465	Phosphorylation	IHTGERPYKCQKCGQ CCCCCCCCCCCCCCC	30.53	27273156

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN559_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN559_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN559_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KRA42_HUMAN	KRTAP4-2	physical	25416956
KR101_HUMAN	KRTAP10-1	physical	25416956
KR103_HUMAN	KRTAP10-3	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.