ZN333_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN333_HUMAN
• UniProt AC: Q96JL9
• Protein Name: Zinc finger protein 333
• Gene Name: ZNF333
• Organism: Homo sapiens (Human).
• Sequence Length: 665
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MESVTFEDVAVEFIQEWALLDSARRSLCKYRMLDQCRTLASRGTPPCKPSCVSQLGQRAEPKATERGILRATGVAWESQLKPEELPSMQDLLEEASSRDMQMGPGLFLRMQLVPSIEERETPLTREDRPALQEPPWSLGCTGLKAAMQIQRVVIPVPTLGHRNPWVARDSAVPARDPAWLQEDKVEEEAMAPGLPTACSQEPVTFADVAVVFTPEEWVFLDSTQRSLYRDVMLENYRNLASVADQLCKPNALSYLEERGEQWTTDRGVLSDTCAEPQCQPQEAIPSQDTFTEILSIDVKGEQPQPGEKLYKYNELEKPFNSIEPLFQYQRIHAGEASCECQEIRNSFFQSAHLIVPEKIRSGDKSYACNKCEKSFRYSSDLIRHEKTHTAEKCFDCQECGQAFKYSSNLRRHMRTHTGEKPFECSQCGKTFTRNFNLILHQRNHTGEKPYECKDCGKAFNQPSSLRSHVRTHTGEKPFECSQCGKAFREHSSLKTHLRTHTREKPYECNQCGKPFRTSTHLNVHKRIHTGEKLYECATCGQVLSRLSTLKSHMRTHTGEKPYVCQECGRAFSEPSSLRKHARTHSGKKPYACQECGRAFGQSSHLIVHVRTHSAGRPYQCNQCEKAFRHSSSLTVHKRTHVGRETIRNGSLPLSMSHPYCGPLAN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
41	Phosphorylation	DQCRTLASRGTPPCK HHHHHHHHCCCCCCC	34.06	-
44	Phosphorylation	RTLASRGTPPCKPSC HHHHHCCCCCCCHHH	23.97	27251275
50	Phosphorylation	GTPPCKPSCVSQLGQ CCCCCCHHHHHHCCC	16.79	27251275
53	Phosphorylation	PCKPSCVSQLGQRAE CCCHHHHHHCCCCCC	24.82	27251275
115	Phosphorylation	LRMQLVPSIEERETP HEEEECCCHHHCCCC	34.84	24719451
124	Phosphorylation	EERETPLTREDRPAL HHCCCCCCCCCCHHH	32.96	24719451
241	Phosphorylation	ENYRNLASVADQLCK HHHHHHHHHHHHHCC	22.47	27732954
312	Phosphorylation	PGEKLYKYNELEKPF CCCCCCCHHCCCCCC	10.58	30622161
361	Phosphorylation	IVPEKIRSGDKSYAC ECCHHHCCCCCCCCC	55.61	-
365	Phosphorylation	KIRSGDKSYACNKCE HHCCCCCCCCCCCCC	23.78	-
366	Phosphorylation	IRSGDKSYACNKCEK HCCCCCCCCCCCCCH	22.40	-
379	Phosphorylation	EKSFRYSSDLIRHEK CHHCCCCHHHHHCCC	27.74	27499020
405	Phosphorylation	ECGQAFKYSSNLRRH HHHHHHHHCHHHHHH	15.75	22817900
415	Phosphorylation	NLRRHMRTHTGEKPF HHHHHHHHCCCCCCE	19.06	-
417	Phosphorylation	RRHMRTHTGEKPFEC HHHHHHCCCCCCEEC	46.56	-
453	Sumoylation	GEKPYECKDCGKAFN CCCCCCCCCHHHHHC	44.08	-
453	Sumoylation	GEKPYECKDCGKAFN CCCCCCCCCHHHHHC	44.08	-
471	Phosphorylation	SLRSHVRTHTGEKPF HHHHHHHHCCCCCCC	23.77	-
473	Phosphorylation	RSHVRTHTGEKPFEC HHHHHHCCCCCCCCC	46.56	-
555	Phosphorylation	TLKSHMRTHTGEKPY HHHHHHCCCCCCCCE	19.06	-
557	Phosphorylation	KSHMRTHTGEKPYVC HHHHCCCCCCCCEEH	46.56	-
583	Phosphorylation	SLRKHARTHSGKKPY HHHHHHHHCCCCCCC	22.60	-
585	Phosphorylation	RKHARTHSGKKPYAC HHHHHHCCCCCCCHH	52.25	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN333_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN333_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN333_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
KDM1A_HUMAN	KDM1A	physical	23455924
TIF1B_HUMAN	TRIM28	physical	26186194
TYK2_HUMAN	TYK2	physical	26186194
ARL15_HUMAN	ARL15	physical	28514442
ASPM_HUMAN	ASPM	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.