ZN205_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZN205_HUMAN
• UniProt AC: O95201
• Protein Name: Zinc finger protein 205
• Gene Name: ZNF205
• Organism: Homo sapiens (Human).
• Sequence Length: 554
• Subcellular Localization: Nucleus .
• Protein Description: May be involved in transcriptional regulation..
• Protein Sequence: MSADGGGIQDTQDKETPPEVPDRGHPHQEMPSKLGEAVPSGDTQESLHIKMEPEEPHSEGASQEDGAQGAWGWAPLSHGSKEKALFLPGGALPSPRIPVLSREGRTRDRQMAAALLTAWSQMPVTFEDVALYLSREEWGRLDHTQQNFYRDVLQKKNGLSLGFPFSRPFWAPQAHGKGEASGSSRQAGDEKEWRGACTGAVEVGQRVQTSSVAALGNVKPFRTRAGRVQWGVPQCAQEAACGRSSGPAKDSGQPAEPDRTPDAAPPDPSPTEPQEYRVPEKPNEEEKGAPESGEEGLAPDSEVGRKSYRCEQCGKGFSWHSHLVTHRRTHTGEKPYACTDCGKRFGRSSHLIQHQIIHTGEKPYTCPACRKSFSHHSTLIQHQRIHTGEKPYVCDRCAKRFTRRSDLVTHQGTHTGAKPHKCPICAKCFTQSSALVTHQRTHTGVKPYPCPECGKCFSQRSNLIAHNRTHTGEKPYHCLDCGKSFSHSSHLTAHQRTHRGVRPYACPLCGKSFSRRSNLHRHEKIHTTGPKALAMLMLGAAAAGALATPPPAPT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
94	Phosphorylation	LPGGALPSPRIPVLS ECCCCCCCCCCCCCC	27.88	29396449
183	Phosphorylation	GKGEASGSSRQAGDE CCCCCCCCCCCCCCH	21.61	30631047
198	Phosphorylation	KEWRGACTGAVEVGQ HHHCCCCCCCHHCCC	27.86	-
219	Acetylation	VAALGNVKPFRTRAG CEECCCCCCCCCCCC	42.30	26051181
219	Sumoylation	VAALGNVKPFRTRAG CEECCCCCCCCCCCC	42.30	28112733
219	Sumoylation	VAALGNVKPFRTRAG CEECCCCCCCCCCCC	42.30	-
292	Phosphorylation	EEKGAPESGEEGLAP CCCCCCCCCCCCCCC	50.90	25159151
305	Methylation	APDSEVGRKSYRCEQ CCCCCCCCCEEECCC	29.89	115383929
329	Phosphorylation	HLVTHRRTHTGEKPY HHEEECCCCCCCCCE	24.60	-
331	Phosphorylation	VTHRRTHTGEKPYAC EEECCCCCCCCCEEE	46.56	-
359	Phosphorylation	IQHQIIHTGEKPYTC HEEEEEECCCCCCCC	36.31	27251275
372	Phosphorylation	TCPACRKSFSHHSTL CCHHHHHHCCCCCHH	16.78	28555341
387	Phosphorylation	IQHQRIHTGEKPYVC EEECCCCCCCCCCCC	44.67	28111955
392	Phosphorylation	IHTGEKPYVCDRCAK CCCCCCCCCCHHHHH	25.44	22210691
402	Phosphorylation	DRCAKRFTRRSDLVT HHHHHHHHHHHHHCC	29.25	22210691
443	Phosphorylation	VTHQRTHTGVKPYPC EECCCCCCCCCCEEC	42.95	28555341
469	Phosphorylation	NLIAHNRTHTGEKPY CCEECCCCCCCCCCE	29.16	-
471	Phosphorylation	IAHNRTHTGEKPYHC EECCCCCCCCCCEEE	46.56	-
512	Phosphorylation	ACPLCGKSFSRRSNL CCCCCCCCCCCCCCC	17.46	27251275
514	Phosphorylation	PLCGKSFSRRSNLHR CCCCCCCCCCCCCCC	33.60	17081983
527	Phosphorylation	HRHEKIHTTGPKALA CCCCCCCCCCHHHHH	36.60	-
528	Phosphorylation	RHEKIHTTGPKALAM CCCCCCCCCHHHHHH	37.01	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZN205_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZN205_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZN205_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
CC85B_HUMAN	CCDC85B	physical	16189514
CACO2_HUMAN	CALCOCO2	physical	16189514

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.