ZFP2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: ZFP2_HUMAN
• UniProt AC: Q6ZN57
• Protein Name: Zinc finger protein 2 homolog
• Gene Name: ZFP2
• Organism: Homo sapiens (Human).
• Sequence Length: 461
• Subcellular Localization: Nucleus .
• Protein Description: Probable transcription factor involved in neuronal differentiation and/or phenotypic maintenance..
• Protein Sequence: MEREGIWHSTLGETWEPNNWLEGQQDSHLSQVGVTHKETFTEMRVCGGNEFERCSSQDSILDTQQSIPMVKRPHNCNSHGEDATQNSELIKTQRMFVGKKIYECNQCSKTFSQSSSLLKHQRIHTGEKPYKCNVCGKHFIERSSLTVHQRIHTGEKPYKCNECGKAFSQSMNLTVHQRTHTGEKPYQCKECGKAFHKNSSLIQHERIHTGEKPYKCNECGKAFTQSMNLTVHQRTHTGEKPYECNECGKAFSQSMHLIVHQRSHTGEKPYECSQCGKAFSKSSTLTLHQRNHTGEKPYKCNKCGKSFSQSTYLIEHQRLHSGVKPFECNECGKAFSKNSSLTQHRRIHTGEKPYECMVCGKHFTGRSSLTVHQVIHTGEKPYECNECGKAFSQSAYLIEHQRIHTGEKPYECDQCGKAFIKNSSLTVHQRTHTGEKPYQCNECGKAFSRSTNLTRHQRTHT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
110	Phosphorylation	ECNQCSKTFSQSSSL ECCCCCCCCCCCHHH	16.54	-
114	Phosphorylation	CSKTFSQSSSLLKHQ CCCCCCCCHHHHHHC	22.24	-
116	Phosphorylation	KTFSQSSSLLKHQRI CCCCCCHHHHHHCCC	42.86	24719451
125	Phosphorylation	LKHQRIHTGEKPYKC HHHCCCCCCCCCEEC	44.67	29496963
153	Phosphorylation	TVHQRIHTGEKPYKC EEEEECCCCCCCEEC	44.67	29496963
158	Phosphorylation	IHTGEKPYKCNECGK CCCCCCCEECCCCHH	38.96	18767875
159	Sumoylation	HTGEKPYKCNECGKA CCCCCCEECCCCHHH	38.83	-
159	Sumoylation	HTGEKPYKCNECGKA CCCCCCEECCCCHHH	38.83	-
168	Phosphorylation	NECGKAFSQSMNLTV CCCHHHHHHHCCCEE	26.63	30576142
174	Phosphorylation	FSQSMNLTVHQRTHT HHHHCCCEEEECCCC	15.78	30576142
179	Phosphorylation	NLTVHQRTHTGEKPY CCEEEECCCCCCCCE	19.74	-
181	Phosphorylation	TVHQRTHTGEKPYQC EEEECCCCCCCCEEC	46.56	-
209	Phosphorylation	IQHERIHTGEKPYKC CCCCEECCCCCCEEC	44.67	29496963
214	Phosphorylation	IHTGEKPYKCNECGK ECCCCCCEECCCCHH	38.96	18767875
215	Sumoylation	HTGEKPYKCNECGKA CCCCCCEECCCCHHH	38.83	-
215	Sumoylation	HTGEKPYKCNECGKA CCCCCCEECCCCHHH	38.83	-
235	Phosphorylation	NLTVHQRTHTGEKPY CCEEEECCCCCCCCE	19.74	28348404
237	Phosphorylation	TVHQRTHTGEKPYEC EEEECCCCCCCCEEC	46.56	29496963
240	Ubiquitination	QRTHTGEKPYECNEC ECCCCCCCCEECCCH	55.00	-
242	Phosphorylation	THTGEKPYECNECGK CCCCCCCEECCCHHH	44.15	-
299	Trimethylation	HTGEKPYKCNKCGKS CCCCCCEECCCCCCC	39.60	-
299	Methylation	HTGEKPYKCNKCGKS CCCCCCEECCCCCCC	39.60	23644510
336	Phosphorylation	NECGKAFSKNSSLTQ CCCHHHHCCCCCCCC	35.47	23909892
339	Phosphorylation	GKAFSKNSSLTQHRR HHHHCCCCCCCCCCC	30.38	23909892
340	Phosphorylation	KAFSKNSSLTQHRRI HHHCCCCCCCCCCCE	44.84	23909892
342	Phosphorylation	FSKNSSLTQHRRIHT HCCCCCCCCCCCEEC	25.03	23909892
349	Phosphorylation	TQHRRIHTGEKPYEC CCCCCEECCCCCEEE	44.67	28111955
377	Phosphorylation	TVHQVIHTGEKPYEC EEEEEEECCCCCEEC	35.59	28152594
380	Ubiquitination	QVIHTGEKPYECNEC EEEECCCCCEECCCC	55.00	-
382	Phosphorylation	IHTGEKPYECNECGK EECCCCCEECCCCHH	44.15	28152594
405	Phosphorylation	IEHQRIHTGEKPYEC EEECCCCCCCCCCCC	44.67	21712546
431	Phosphorylation	SLTVHQRTHTGEKPY CCEEEECCCCCCCCE	19.74	-
433	Phosphorylation	TVHQRTHTGEKPYQC EEEECCCCCCCCEEC	46.56	-
438	Phosphorylation	THTGEKPYQCNECGK CCCCCCCEECCCCCC	36.44	-

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of ZFP2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of ZFP2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of ZFP2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TRI41_HUMAN	TRIM41	physical	25416956
K1C40_HUMAN	KRT40	physical	25416956
BN3D2_HUMAN	BCDIN3D	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.