| UniProt ID | YIPF1_HUMAN | |
|---|---|---|
| UniProt AC | Q9Y548 | |
| Protein Name | Protein YIPF1 | |
| Gene Name | YIPF1 | |
| Organism | Homo sapiens (Human). | |
| Sequence Length | 306 | |
| Subcellular Localization |
Golgi apparatus, cis-Golgi network membrane Multi-pass membrane protein . Golgi apparatus, trans-Golgi network membrane . Late endosome membrane . Mainly localizes within medial-/trans-Golgi and trans-Golgi network (TGN), while less so within cis-G |
|
| Protein Description | ||
| Protein Sequence | MAAVDDLQFEEFGNAATSLTANPDATTVNIEDPGETPKHQPGSPRGSGREEDDELLGNDDSDKTELLAGQKKSSPFWTFEYYQTFFDVDTYQVFDRIKGSLLPIPGKNFVRLYIRSNPDLYGPFWICATLVFAIAISGNLSNFLIHLGEKTYHYVPEFRKVSIAATIIYAYAWLVPLALWGFLMWRNSKVMNIVSYSFLEIVCVYGYSLFIYIPTAILWIIPQKAVRWILVMIALGISGSLLAMTFWPAVREDNRRVALATIVTIVLLHMLLSVGCLAYFFDAPEMDHLPTTTATPNQTVAAAKSS | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 17 | Phosphorylation | EEFGNAATSLTANPD HHHHCCCHHCCCCCC | 23.12 | 23401153 | |
| 18 | Phosphorylation | EFGNAATSLTANPDA HHHCCCHHCCCCCCC | 20.99 | 23401153 | |
| 20 | Phosphorylation | GNAATSLTANPDATT HCCCHHCCCCCCCCE | 24.93 | 23401153 | |
| 26 | Phosphorylation | LTANPDATTVNIEDP CCCCCCCCEEECCCC | 38.36 | 23401153 | |
| 27 | Phosphorylation | TANPDATTVNIEDPG CCCCCCCEEECCCCC | 17.18 | 23401153 | |
| 36 | Phosphorylation | NIEDPGETPKHQPGS ECCCCCCCCCCCCCC | 43.48 | 23401153 | |
| 39 | Ubiquitination | DPGETPKHQPGSPRG CCCCCCCCCCCCCCC | 40.03 | 27667366 | |
| 43 | Phosphorylation | TPKHQPGSPRGSGRE CCCCCCCCCCCCCCC | 20.36 | 20363803 | |
| 47 | Phosphorylation | QPGSPRGSGREEDDE CCCCCCCCCCCCCCH | 35.64 | 30266825 | |
| 48 | Ubiquitination | PGSPRGSGREEDDEL CCCCCCCCCCCCCHH | 43.79 | 21890473 | |
| 61 | Phosphorylation | ELLGNDDSDKTELLA HHCCCCCCCHHHHHC | 43.82 | 21815630 | |
| 63 | Ubiquitination | LGNDDSDKTELLAGQ CCCCCCCHHHHHCCC | 48.10 | 21890473 | |
| 71 | Ubiquitination | TELLAGQKKSSPFWT HHHHCCCCCCCCCEE | 54.42 | 21906983 | |
| 88 (in isoform 1) | Ubiquitination | - | 5.11 | 21890473 | |
| 96 (in isoform 1) | Ubiquitination | - | 22.51 | 21890473 | |
| 98 | Ubiquitination | YQVFDRIKGSLLPIP HHHHHHHCCCEECCC | 43.26 | 27667366 | |
| 107 | Ubiquitination | SLLPIPGKNFVRLYI CEECCCCCCEEEEEE | 41.69 | 23000965 | |
| 132 (in isoform 1) | Ubiquitination | - | 4.59 | 21890473 | |
| 297 | N-linked_Glycosylation | PTTTATPNQTVAAAK CCCCCCCCCCHHHHC | 45.89 | UniProtKB CARBOHYD |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of YIPF1_HUMAN !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of YIPF1_HUMAN !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of YIPF1_HUMAN !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| YIPF6_HUMAN | YIPF6 | physical | 25416956 | |
| YIPF6_HUMAN | YIPF6 | physical | 28514442 | |
| TPM2_HUMAN | TPM2 | physical | 28514442 |
| Kegg Disease | ||||||
|---|---|---|---|---|---|---|
| There are no disease associations of PTM sites. | ||||||
| OMIM Disease | ||||||
| There are no disease associations of PTM sites. | ||||||
| Kegg Drug | ||||||
| There are no disease associations of PTM sites. | ||||||
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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