Y3427_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: Y3427_DROME
• UniProt AC: Q0KIC3
• Protein Name: Uncharacterized protein CG43427
• Gene Name: CG43427
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 1372
• Protein Sequence: MEATDQEVMLEGREDLMSTSATSSTNGGDTNGCGKKLSVTSPDPTPYVTKQRVTRPTPPAPSKNPMQFVQIKPCNLYQTAQEQLKKAEEVKKLKEVKKEEPEEWQNNLDNWKSSRRKRVEHIIDRAVETKKLELEEHDRLRRKSKTFTEMMEERAERGGPRGRAKLASLAVYNEDETNDLSDLGIGTSSASGKSSLSGDYDNNSVMSDHAAELDKAIGAASSVAAGVTAQNVDEQLNHINRNGSNGNHGNGAAVGQTGPSNSSKSAGRQYISSPGYDTSSSNAQASSPDLCEYTYEGAIQDYKQRVQRASSNGNGNANGKLIGEHIAYPTRRGSKIEDRLSGFEVTSPSDTQEGVEKQKVDVPKVDISKRKEIFEQAKAEVSNGGAPAAPKLVFRDGLTNGNSATTAPKSEVRRLSGDISSIRDRMQSLEQQRKAFSSSKSVDVPVPPLKQRLNSLQQSVAKEEQKKPPLVALIDARQLEIMRGEEERMRQQQQKEKHSPSQTTLCAPKPAPPALIIEEPPVADTNDDSGIQEDTADELQQQQQLNAAIAALALEERQLEEAANAVNQIEAEFDELTDLHPSPLPPSPALPAVQQSLQQPTVAQVPAQAVNQAAAPPLRDMEFSVSCTNNFIEPAKISPCDVNVVAASAVSVSKSGPTPNPTSTPNMVSSSPNCNLRRKPSNEMVHHRNLLKMFKETFQNDDDLKEVCEIVTSPGQFTQIIDFSKRPSNPPIPIPTLLPTSTPIPTQIPRPLGKPPMSPKAVRLASSPKGHINPLSSPTNSGFSPPQFSINGRVEIFNSRQLDKPPTPPAPPKKTVRSEHPLKEAVPSPEVVMCAPPMTIVDPDELPKPNTVKALSNCFSQSDSKSLTSPIMSPKPLPSGRIPQITPPASPKPPKRVQLDEVDRSSGDYAPVVGQTKAIVHTPPSKINARANQTLDPLAPNDSLCLHTSSPSEIPSLKACSPNESSLFKLASSRPTSPSVDVASCQKFLNREAPKDIQLAEEDRKRMDQFAVEEMPCDKIDVTKSPQPNTGFQIVTEDLVKKCDGKNISEAVRDLDVPPSQEDIALCAGLLDCLAPAQEPICDSIDVRNGPVPATGFQDISEEEVKKCEKHNKNYVITNRPSSPIGSVRAAHSKALMDTCEQIIAEERKASSQMMKTSLPESVEKPSTPLPGRKSKIPIPKPCCISASGTDSISRAGYVPTAPSHLSGSAQQPLIARTHVVETEIKVKEISPPSIPKTPEQTQLHASPTKEKKAKNIFDFLRRNFGHQEEPQHHSTLNETLEKKVVLTSTKSGVDVVNADEFVRVDNSKFYLASELEDVPVPPPLPKTPAPVNIEIRKKITTNEILEENTTEQALTQEISDLLDDEIMKLEN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
38	Phosphorylation	NGCGKKLSVTSPDPT CCCCCCCEECCCCCC	32.03	21082442
207	Phosphorylation	YDNNSVMSDHAAELD CCCCCCHHHHHHHHH	24.88	27794539
330	Phosphorylation	GEHIAYPTRRGSKIE CEEECCCCCCCCCHH	21.96	27794539
334	Phosphorylation	AYPTRRGSKIEDRLS CCCCCCCCCHHHHHC	28.75	27794539
416	Phosphorylation	KSEVRRLSGDISSIR HHHHHHHHCCHHHHH	32.38	19429919
428	Phosphorylation	SIRDRMQSLEQQRKA HHHHHHHHHHHHHHH	25.24	21082442
441	Phosphorylation	KAFSSSKSVDVPVPP HHHHCCCCCCCCCCC	26.04	21082442
455	Phosphorylation	PLKQRLNSLQQSVAK CHHHHHHHHHHHHHH	31.95	21082442
681	Phosphorylation	CNLRRKPSNEMVHHR CCCCCCCCCCHHHHH	48.75	21082442
758	Phosphorylation	PLGKPPMSPKAVRLA CCCCCCCCHHHHHHC	29.08	21082442
777	Phosphorylation	GHINPLSSPTNSGFS CCCCCCCCCCCCCCC	43.35	21082442
781	Phosphorylation	PLSSPTNSGFSPPQF CCCCCCCCCCCCCCC	43.63	21082442
873	Phosphorylation	SLTSPIMSPKPLPSG CCCCCCCCCCCCCCC	30.41	27626673
886	Phosphorylation	SGRIPQITPPASPKP CCCCCCCCCCCCCCC	20.26	25749252
890	Phosphorylation	PQITPPASPKPPKRV CCCCCCCCCCCCCCE	38.95	25749252
906	Phosphorylation	LDEVDRSSGDYAPVV CCCCCCCCCCCCCCC	36.26	22668510
976	Phosphorylation	KLASSRPTSPSVDVA HHHHCCCCCCCCCHH	52.76	29892262
977	Phosphorylation	LASSRPTSPSVDVAS HHHCCCCCCCCCHHH	20.19	29892262
979	Phosphorylation	SSRPTSPSVDVASCQ HCCCCCCCCCHHHHH	30.62	23607784
1118	Phosphorylation	HNKNYVITNRPSSPI CCCCEEEECCCCCCC	18.35	19429919
1122	Phosphorylation	YVITNRPSSPIGSVR EEEECCCCCCCCCHH	45.57	19429919
1123	Phosphorylation	VITNRPSSPIGSVRA EEECCCCCCCCCHHH	24.18	19429919
1127	Phosphorylation	RPSSPIGSVRAAHSK CCCCCCCCHHHHHHH	14.78	19429919
1162	Phosphorylation	MKTSLPESVEKPSTP HHHCCCCCCCCCCCC	33.37	22668510
1167	Phosphorylation	PESVEKPSTPLPGRK CCCCCCCCCCCCCCC	54.44	21082442
1168	Phosphorylation	ESVEKPSTPLPGRKS CCCCCCCCCCCCCCC	37.05	22668510
1247	Phosphorylation	EQTQLHASPTKEKKA HHCCCCCCCCHHHHH	23.50	22668510
1249	Phosphorylation	TQLHASPTKEKKAKN CCCCCCCCHHHHHHH	49.71	22668510

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of Y3427_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of Y3427_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of Y3427_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SRC42_DROME	Src42A	physical	14605208
RS8_DROME	RpS8	physical	14605208
GALT1_DROME	GalNAc-T1	physical	14605208
EXOC2_DROME	Sec5	physical	14605208

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.