dbPTM

XPF_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	XPF_DROME
UniProt AC	Q24087
Protein Name	DNA repair endonuclease XPF
Gene Name	mei-9
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	961
Subcellular Localization	Nucleus .
Protein Description	Implicated in recombination events during meiosis, mostly in meiotic exchange. May directly resolve Holliday junctions within recombination intermediates leading to DNA exchange. Also required for the repair of mismatches within meiotic heteroduplex DNA and for nucleotide excision repair..
Protein Sequence	MADSCAENAAKGTENERPKEVEASADTVPQVEEGVEEYLKRKNMVLLDYEKQMFLDLVEADGLLVCAKGLSYDRVVISILKAYSDSGNLVLVINSSDWEEQYYKSKIEPKYVHEVASTATERERVYLEGGLQFISTRILVVDLLKQRIPIELISGIIVLRAHTIIESCQEAFALRLFRQKNKTGFVKAFSSSPEAFTIGYSHVERTMRNLFVKHLYIWPRFHESVRTVLQPWKIQSIEMHVPISQNITSIQSHILEIMNFLVQEIKRINRTVDMEAVTVENCVTKSFHKILQAQLDCIWHQLNSQTKLIVADLKILRSLMISTMYHDAVSAYAFMKRYRSTEYALSNSGWTLLDAAEQIFKLSRQRVFNGQQEFEPEPCPKWQTLTDLLTKEIPGDMRRSRRSEQQPKVLILCQDARTCHQLKQYLTQGGPRFLLQQALQHEVPVGKLSDNYAKESQTRSAPPKNVSSNKELRREEVSGSQPPLAGMDELAQLLSESETEGQHFEESYMLTMTQPVEVGPAAIDIKPDPDVSIFETIPELEQFDVTAALASVPHQPYICLQTFKTEREGSMALEHMLEQLQPHYVVMYNMNVTAIRQLEVFEARRRLPPADRMKVYFLIHARTVEEQAYLTSLRREKAAFEFIIDTKSKMVIPKYQDGKTDEAFLLLKTYDDEPTDENAKSRQAGGQAPQATKETPKVIVDMREFRSDLPCLIHKRGLEVLPLTITIGDYILTPDICVERKSISDLIGSLNSGRLYNQCVQMQRHYAKPILLIEFDQNKPFHLQGKFMLSQQTSMANADIVQKLQLLTLHFPKLRLIWSPSPYATAQLFEELKLGKPEPDPQTAAALGSDEPTAGEQLHFNSGIYDFLLRLPGVHTRNIHGLLRKGGSLRQLLLRSQKELEELLQSQESAKLLYDILHVAHLPEKDEVTGSTALLAASKQFGAGSHNRFRMAAAASRRGRR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of XPF_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of XPF_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of XPF_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of XPF_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SLX4_DROME	mus312	physical	12504024
HDM_DROME	hdm	physical	18957705
SLX4_DROME	mus312	physical	15166153

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of XPF_DROME

Related Literatures of Post-Translational Modification