dbPTM

HDM_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	HDM_DROME
UniProt AC	Q9W3M9
Protein Name	Protein hold'em
Gene Name	hdm
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	486
Subcellular Localization
Protein Description	Single-stranded DNA-binding protein required for meiosis. May be involved in the resolution of recombination intermediates into crossovers in the meiotic recombination pathway..
Protein Sequence	MARRIKFQRLAEMRPTMTRFSTVALIVSKSSPNIFYDKMSGTERGVLSLTIRDSPNHLTNCKCWGQRDCVDEYAAMLQIGHVVDIVGAKVMSIPFAAPGEQRYQPQATVSCALVVNEGSGYVVRHDNDDFGQITILQQLLHQPIRPLGAVLKLADVRSGLGFPDKIITTNVNLLVVVAAVRPVRQIKRKLQGPLSEVQELLQCLEVIVIDASYPEGMLLSVWQPDWIQRAQQWQPRRTVLHLIDVRVSYSNFHRSLVLSHSNCTLICENPQAAGDDCRLLLAFAATVPLTTFSGCDQAELDNMPAVASIQAQMTVRQIYSRAEGELQDPSIHQFTAVLYGMVTKFDLDGLTSHVNRKCIACQQHIPRNLQDCASDACQQYFSLDNDEPRSISYFNINIHLSDQTGTLVEARLAGHPAERILGLRAEDFERLAEREKSELKWRFLLKYFEVRLMIKKPVGVRNHLVIVVVDMQAIPLEKLVANMVVF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
Oops, there are no PTM records of HDM_DROME !!

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of HDM_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of HDM_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of HDM_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
SIR2_DROME	Sir2	genetic	20711363
MCMR_DROME	rec	genetic	18957704

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of HDM_DROME

Related Literatures of Post-Translational Modification