UBFD1_HUMAN - dbPTM
UBFD1_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID UBFD1_HUMAN
UniProt AC O14562
Protein Name Ubiquitin domain-containing protein UBFD1
Gene Name UBFD1
Organism Homo sapiens (Human).
Sequence Length 309
Subcellular Localization
Protein Description May play a role as NF-kappa-B regulator..
Protein Sequence MAAAGAPDGMEEPGMDTEAETVATEAPARPVNCLEAEAAAGAAAEDSGAARGSLQPAPAQPPGDPAAQASVSNGEDAGGGAGRELVDLKIIWNKTKHDVKFPLDSTGSELKQKIHSITGLPPAMQKVMYKGLVPEDKTLREIKVTSGAKIMVVGSTINDVLAVNTPKDAAQQDAKAEENKKEPLCRQKQHRKVLDKGKPEDVMPSVKGAQERLPTVPLSGMYNKSGGKVRLTFKLEQDQLWIGTKERTEKLPMGSIKNVVSEPIEGHEDYHMMAFQLGPTEASYYWVYWVPTQYVDAIKDTVLGKWQYF
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
70PhosphorylationGDPAAQASVSNGEDA
CCHHHHHHCCCCCCC		17.6319060867
72PhosphorylationPAAQASVSNGEDAGG
HHHHHHCCCCCCCCC		36.3026657352
89UbiquitinationGRELVDLKIIWNKTK
CCEEEEEEEEEECCC		27.9032015554
94UbiquitinationDLKIIWNKTKHDVKF
EEEEEEECCCCCCCC		43.9121890473
94UbiquitinationDLKIIWNKTKHDVKF
EEEEEEECCCCCCCC		43.9127667366
96UbiquitinationKIIWNKTKHDVKFPL
EEEEECCCCCCCCCC		39.1422817900
100UbiquitinationNKTKHDVKFPLDSTG
ECCCCCCCCCCCCCC		47.5221890473
100UbiquitinationNKTKHDVKFPLDSTG
ECCCCCCCCCCCCCC		47.5227667366
106PhosphorylationVKFPLDSTGSELKQK
CCCCCCCCCHHHHHH		44.3825627689
108PhosphorylationFPLDSTGSELKQKIH
CCCCCCCHHHHHHHH		39.5825627689
111UbiquitinationDSTGSELKQKIHSIT
CCCCHHHHHHHHHHH		45.5621890473
111UbiquitinationDSTGSELKQKIHSIT
CCCCHHHHHHHHHHH		45.5627667366
113UbiquitinationTGSELKQKIHSITGL
CCHHHHHHHHHHHCC		40.5822817900
113UbiquitinationTGSELKQKIHSITGL
CCHHHHHHHHHHHCC		40.5821890473
116PhosphorylationELKQKIHSITGLPPA
HHHHHHHHHHCCCHH		25.8921406692
118PhosphorylationKQKIHSITGLPPAMQ
HHHHHHHHCCCHHHH		35.3630266825
126UbiquitinationGLPPAMQKVMYKGLV
CCCHHHHHHHHCCCC		18.8421890473
126UbiquitinationGLPPAMQKVMYKGLV
CCCHHHHHHHHCCCC		18.8423000965
126AcetylationGLPPAMQKVMYKGLV
CCCHHHHHHHHCCCC		18.8423954790
130UbiquitinationAMQKVMYKGLVPEDK
HHHHHHHCCCCCCCC		27.8923000965
137UbiquitinationKGLVPEDKTLREIKV
CCCCCCCCCHHEEEE		48.0433845483
143UbiquitinationDKTLREIKVTSGAKI
CCCHHEEEECCCCEE		34.4127667366
146PhosphorylationLREIKVTSGAKIMVV
HHEEEECCCCEEEEE		39.4822817900
149UbiquitinationIKVTSGAKIMVVGST
EEECCCCEEEEEECC		34.5622817900
149UbiquitinationIKVTSGAKIMVVGST
EEECCCCEEEEEECC		34.5621890473
151SulfoxidationVTSGAKIMVVGSTIN
ECCCCEEEEEECCHH		1.6521406390
165PhosphorylationNDVLAVNTPKDAAQQ
HHHHCCCCCHHHHHH		25.7227050516
167UbiquitinationVLAVNTPKDAAQQDA
HHCCCCCHHHHHHHH		58.9421906983
175UbiquitinationDAAQQDAKAEENKKE
HHHHHHHHHHHHCCC		65.7033845483
180UbiquitinationDAKAEENKKEPLCRQ
HHHHHHHCCCCCHHH		62.8929967540
181UbiquitinationAKAEENKKEPLCRQK
HHHHHHCCCCCHHHH		75.9329967540
196UbiquitinationQHRKVLDKGKPEDVM
HHHHHHHCCCHHHCC		65.7524816145
196AcetylationQHRKVLDKGKPEDVM
HHHHHHHCCCHHHCC		65.7525953088
203SulfoxidationKGKPEDVMPSVKGAQ
CCCHHHCCCCCCCHH		2.9530846556
207UbiquitinationEDVMPSVKGAQERLP
HHCCCCCCCHHHHCC		53.5223503661
219PhosphorylationRLPTVPLSGMYNKSG
HCCCCCCCEEEECCC		18.5529759185
222PhosphorylationTVPLSGMYNKSGGKV
CCCCCEEEECCCCEE		23.9829759185
224MalonylationPLSGMYNKSGGKVRL
CCCEEEECCCCEEEE		32.7526320211
224UbiquitinationPLSGMYNKSGGKVRL
CCCEEEECCCCEEEE		32.7522817900
225PhosphorylationLSGMYNKSGGKVRLT
CCEEEECCCCEEEEE		49.4929759185
228UbiquitinationMYNKSGGKVRLTFKL
EEECCCCEEEEEEEE		27.9222817900
245UbiquitinationDQLWIGTKERTEKLP
CEEEEEECCCCCCCC		39.7323000965
245UbiquitinationDQLWIGTKERTEKLP
CEEEEEECCCCCCCC		39.7321890473
245MalonylationDQLWIGTKERTEKLP
CEEEEEECCCCCCCC		39.7332601280
250MalonylationGTKERTEKLPMGSIK
EECCCCCCCCCCCCE		58.2226320211
250UbiquitinationGTKERTEKLPMGSIK
EECCCCCCCCCCCCE		58.2223000965
299UbiquitinationTQYVDAIKDTVLGKW
HHHHHHHHHHHCCCC		49.4123000965
305UbiquitinationIKDTVLGKWQYF---
HHHHHCCCCCCC---		27.2821890473
305UbiquitinationIKDTVLGKWQYF---
HHHHHCCCCCCC---		27.2823000965
308PhosphorylationTVLGKWQYF------
HHCCCCCCC------		15.33-
318Ubiquitination----------------
----------------		21890473
324Ubiquitination----------------------
----------------------		21890473
335Ubiquitination---------------------------------
---------------------------------		21890473
337Ubiquitination-----------------------------------
-----------------------------------		21890473
350Ubiquitination------------------------------------------------
------------------------------------------------		21890473
373Ubiquitination-----------------------------------------------------------------------
-----------------------------------------------------------------------		21890473
391Ubiquitination-----------------------------------------------------------------------------------------
-----------------------------------------------------------------------------------------		21890473
448Ubiquitination--------------------------------------------------------------------------------------------------------------------------------------------------
--------------------------------------------------------------------------------------------------------------------------------------------------		21890473
469Ubiquitination-----------------------------------------------------------------------------------------------------------------------------------------------------------------------
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------		21890473
529Ubiquitination-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------
-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------		21890473
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of UBFD1_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of UBFD1_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of UBFD1_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
HNRPK_HUMANHNRNPKphysical
22863883
RUXF_HUMANSNRPFphysical
22863883
IF4E_HUMANEIF4Ephysical
26344197
Drug and Disease Associations
Kegg Disease
There are no disease associations of PTM sites.
OMIM Disease
There are no disease associations of PTM sites.
Kegg Drug
There are no disease associations of PTM sites.
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of UBFD1_HUMAN

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Related Literatures of Post-Translational Modification

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