U1SBP_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: U1SBP_HUMAN
• UniProt AC: Q16560
• Protein Name: U11/U12 small nuclear ribonucleoprotein 35 kDa protein
• Gene Name: SNRNP35
• Organism: Homo sapiens (Human).
• Sequence Length: 246
• Subcellular Localization: Nucleus .
• Protein Sequence: MNDWMPIAKEYDPLKAGSIDGTDEDPHDRAVWRAMLARYVPNKGVIGDPLLTLFVARLNLQTKEDKLKEVFSRYGDIRRLRLVRDLVTGFSKGYAFIEYKEERAVIKAYRDADGLVIDQHEIFVDYELERTLKGWIPRRLGGGLGGKKESGQLRFGGRDRPFRKPINLPVVKNDLYREGKRERRERSRSRERHWDSRTRDRDHDRGREKRWQEREPTRVWPDNDWERERDFRDDRIKGREKKERGK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
88	Phosphorylation	RLVRDLVTGFSKGYA HHHHHHHHHCCCCEE	39.54	20068231
91	Phosphorylation	RDLVTGFSKGYAFIE HHHHHHCCCCEEEEE	26.90	21712546
131	Phosphorylation	VDYELERTLKGWIPR EEHHHHHHHCCCCCC	24.36	-
147	Acetylation	LGGGLGGKKESGQLR CCCCCCCCCCCCCCC	52.12	7681329
148	Acetylation	GGGLGGKKESGQLRF CCCCCCCCCCCCCCC	61.46	7350231
172	Sumoylation	PINLPVVKNDLYREG CCCCCCCCCHHHHHH	45.00	28112733
180	Ubiquitination	NDLYREGKRERRERS CHHHHHHHHHHHHHH	46.46	-
187	Phosphorylation	KRERRERSRSRERHW HHHHHHHHHHHHHHH	29.83	20068231
189	Phosphorylation	ERRERSRSRERHWDS HHHHHHHHHHHHHHH	39.48	20068231

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of U1SBP_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of U1SBP_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of U1SBP_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
PDCD7_HUMAN	PDCD7	physical	28514442
RBM40_HUMAN	RNPC3	physical	28514442
SNR48_HUMAN	SNRNP48	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.