TRI67_MOUSE - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TRI67_MOUSE
• UniProt AC: Q505D9
• Protein Name: Tripartite motif-containing protein 67
• Gene Name: Trim67
• Organism: Mus musculus (Mouse).
• Sequence Length: 768
• Subcellular Localization: Cytoplasm. Cytoplasm, cytoskeleton. Microtubule-associated..
• Protein Sequence: MEEELKCPVCGSLFREPIILPCSHNVCLPCARTIAVQTPDGEQHLPPPLLLSRGAAAAATPPDQDAAAGATSGGAGANTAGGLGGGATGGGDHADKLSLYSETDSGYGSYTPSLKSPNGVRVLPMVPAPPGSSAAAARGAACSSLCSSSSSITCPQCHRSASLDHRGLRGFQRNRLLEGIVQRYQQGRGVVPGAAAAPAVAICQLCDRTPPEPAATLCEQCDVLYCATCQLKCHPSRGPFAKHRLVQPPPPPTPPEATPAVTGTSTASSAGGCRSPGGAGASAPRKFPTCPEHEMENYSMYCVSCRSPVCYMCLEEGRHSKHEVKPLGATWKQHKAQLSQALNGVSDKAKEAKEFLVQLKNILQQIQENGLDYEACLVAQCDALVDALTRQKAKLLTKVTKEREHKLKMVWDQINHCTLKLRQSTGLMEYCLEVIKEDDPSGFLQISDALIKRVQTSQEQWVKGALEPKVSAEFDLTLDSEPLLQAIHQLDFVQMKLPPVPLLQLEKCCTRNNSVTLAWRTPPFTHSPAEGYILELDDGDGGQFREVYVGKETLCTIDGLHFNSTYNARVKAFNSSGVGPYSKTVVLQTSDVAWFTFDPNSGHRDIILSNDNQTATCSSYDDRVVLGTAAFSKGVHYWELHVDRYDNHPDPAFGVARASVVKDMMLGKDDKAWAMYVDNNRSWFMHCNSHTNRTEGGVCKGATVGVLLDLNKHTLTFFINGQQQGPTAFSHVDGVFMPALSLNRNVQVTLHTGLEVPTNLGRPKLSGN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
33	Phosphorylation	VCLPCARTIAVQTPD CCCCCCCEEEEECCC	8.51	30372032
38	Phosphorylation	ARTIAVQTPDGEQHL CCEEEEECCCCCCCC	19.42	27180971
60	Phosphorylation	RGAAAAATPPDQDAA CCCCCCCCCCCCCHH	30.54	25777480
71	Phosphorylation	QDAAAGATSGGAGAN CCHHCCCCCCCCCCC	27.30	25777480
72	Phosphorylation	DAAAGATSGGAGANT CHHCCCCCCCCCCCC	34.39	25777480
79	Phosphorylation	SGGAGANTAGGLGGG CCCCCCCCCCCCCCC	26.58	25777480
88	Phosphorylation	GGLGGGATGGGDHAD CCCCCCCCCCCCCHH	39.37	25777480
147	O-linked_Glycosylation	AACSSLCSSSSSITC HHHHHHHCCCCCCCC	38.25	30016717
148	O-linked_Glycosylation	ACSSLCSSSSSITCP HHHHHHCCCCCCCCC	32.99	30016717
149	O-linked_Glycosylation	CSSLCSSSSSITCPQ HHHHHCCCCCCCCCC	16.29	30016717
275	Phosphorylation	SSAGGCRSPGGAGAS CCCCCCCCCCCCCCC	31.79	28066266
520	Methylation	NSVTLAWRTPPFTHS CCEEEEEECCCCCCC	31.57	18960215
749	Phosphorylation	LNRNVQVTLHTGLEV CCCCCEEEEECCCCC	8.84	21454597
752	Phosphorylation	NVQVTLHTGLEVPTN CCEEEEECCCCCCCC	46.72	21454597
758	Phosphorylation	HTGLEVPTNLGRPKL ECCCCCCCCCCCCCC	48.53	21454597

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TRI67_MOUSE !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TRI67_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TRI67_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
GLU2B_MOUSE	Prkcsh	physical	22337885
PLPR4_MOUSE	Lppr4	physical	22337885

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.