dbPTM

TRI43_HUMAN - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TRI43_HUMAN
UniProt AC	Q96BQ3
Protein Name	Tripartite motif-containing protein 43
Gene Name	TRIM43
Organism	Homo sapiens (Human).
Sequence Length	446
Subcellular Localization
Protein Description
Protein Sequence	MDSDFSHAFQKELTCVICLNYLVDPVTICCGHSFCRPCLCLSWEEAQSPANCPACREPSPKMDFKTNILLKNLVTIARKASLWQFLSSEKQICGTHRQTKKMFCDMDKSLLCLLCSNSQEHGAHKHHPIEEAAEEHREKLLKQMRILWKKIQENQRNLYEEGRTAFLWRGNVVLRAQMIRNEYRKLHPVLHKEEKQHLERLNKEYQEIFQQLQRSWVKMDQKSKHLKEMYQELMEMCHKPDVELLQDLGDIVARSESVLLHMPQPVNPELTAGPITGLVYRLNRFRVEISFHFEVTNHNIRLFEDVRSWMFRRGPLNSDRSDYFAAWGARVFSFGKHYWELDVDNSCDWALGVCNNSWIRKNSTMVNSEDIFLLLCLKVDNHFNLLTTSPVFPHYIEKPLGRVGVFLDFESGSVSFLNVTKSSLIWSYPAGSLTFPVRPFFYTGHR

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
59	Phosphorylation	CPACREPSPKMDFKT CCCCCCCCCCCCHHH	32.19	24275569
290	Phosphorylation	NRFRVEISFHFEVTN CCCEEEEEEEEEECC	10.12	28842319

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TRI43_HUMAN !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TRI43_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TRI43_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TRI27_HUMAN	TRIM27	physical	22493164
TRIM8_HUMAN	TRIM8	physical	22493164
DHRS4_HUMAN	DHRS4	physical	28514442
CH60_HUMAN	HSPD1	physical	28514442
SIR3_HUMAN	SIRT3	physical	28514442
MIPEP_HUMAN	MIPEP	physical	28514442
IF2M_HUMAN	MTIF2	physical	28514442
CLPX_HUMAN	CLPX	physical	28514442
CLPP_HUMAN	CLPP	physical	28514442

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TRI43_HUMAN

Related Literatures of Post-Translational Modification