TPLAT_ARATH - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TPLAT_ARATH
• UniProt AC: F4J8D3
• Protein Name: Protein TPLATE
• Gene Name: TPLATE
• Organism: Arabidopsis thaliana (Mouse-ear cress).
• Sequence Length: 1176
• Subcellular Localization: Cytoplasm, cytoskeleton, phragmoplast . Localized in the forming cell plate and the cortical division zone (CDZ) during cytokinesis.
• Protein Description: Functions in vesicle-trafficking events required for site-specific cell wall modifications during pollen germination and for anchoring of the cell plate to the mother wall at the correct cortical position..
• Protein Sequence: MDILFAQIQADLRSNDALRQSSALLQALQQSAAGRDISVIAKSAVEEIVASPASAVCKKLAFDLIRSTRLTPDLWDTVCSGVKTDLHFPDPDVTAAAVSILAALPAFSLPKLISDCSSEIASCFDSPSDNLRFSITETLGCILARDDLVTLCENNVGLLDKVSNWWARIGQNMLDKSDAVSKVAFESVGRLFQEFDSKRMSRLAGDKLVDSENSLAIRSKWVSSMVDIVWRKRSALMARSLVLPVETFRATVFPLVFAVKAVASGSVEVIRQLSKASSAAAAANATVVDSNAEKLVGVSDLVTHLAPFLASSLDPALIFEVGINMLYLADVAGGKPEWASQSIIAILTLWDRQEFSSARESIVRAVVTNLHLLDLHMQVSLFRRLLLMVRNLRAESDRMHALACICRTALCVHLFARESARRGQKPLPGTDIISLFEDARIKDDLNSVTSKSLFREELVAMLVESCFQLSLPLPEQKNSGMESRVIGALAYGTGYGALNWTEPALEVVEVCRPCVKWDCDGRTYAVDCYLKLLVRLCHIYDTRGGVKRLKDGASQDQILNETRLQNLQRELVKDLQEVNTPRILGRLIWTIAEHIDLEGLDPLLADDPDDPLNIIIANIHKVLFNLDAAATTSNRLQDVQAVLLCAQRMGSRHARAGQLLTKELEEYRNHAAADTVSKHQTRLILQRIKYVSNLPERKWAGVSETRGDYPFSHHKLTVQFYEPSAAQDRKLEGLIHKAILELWRPKPTELTLFLTKGVDSTSIKVPPTAYPLTGSSDPCYIEAYHLADTNDGRVTLHLKIINLTELELNRVDIRVGLSGALYFMDGSPQAVRQLRNLVSQDPVQCSVTVGVSQFERCGFWVQVLYYPFRGARGEYDGDYIEEDPQIMKQKRGSKAELGEPVILRCQPYKIPLTELLLPHKISPVEFFRLWPSLPAVAEYTGTYMYEGSGFMATAAQQYGASPFLSGLKSLSSKPFHRVCSHIIRTVAGFQLCYAAKTWHGGFVGMMIFGASEVSRNMDLGDETTTMMCKFVVRASEASITKQIESDIQGWCDDLTDGGVEYMPEDEVKATAAEKLKISMERIALLKAAQPKKTSKIEEESENEEEEEGEEEDDDEEVKEKKEKEEGKDKEEKKKKEKEKGTFSKLTAEETEHMALQAAVLQEWHILCKDRKYTKVN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
197	Phosphorylation	RLFQEFDSKRMSRLA HHHHHHCHHHHHHHH	27.73	19880383
277	Phosphorylation	IRQLSKASSAAAAAN HHHHHHHHHHHHHCC	25.01	25561503
278	Phosphorylation	RQLSKASSAAAAANA HHHHHHHHHHHHCCC	27.13	25561503
554	Phosphorylation	KRLKDGASQDQILNE EECCCCCCHHHHHHH	39.56	25368622
690	Phosphorylation	LILQRIKYVSNLPER HHHHHHHHHHCCCCC	13.51	23776212
692	Phosphorylation	LQRIKYVSNLPERKW HHHHHHHHCCCCCCC	29.56	23776212
980	Phosphorylation	KPFHRVCSHIIRTVA CHHHHHHHHHHHHHH	18.18	22074104
993	Phosphorylation	VAGFQLCYAAKTWHG HHHHHHHHHHCCCCC	20.41	22074104
1100	Phosphorylation	TSKIEEESENEEEEE CCCCCHHCCCHHHHC	49.34	30291188

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TPLAT_ARATH !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TPLAT_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TPLAT_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TPLAT_ARATH	TPLATE	physical	21187379
CLC2_ARATH	AT2G40060	physical	21187379
SNF12_ARATH	CHC1	physical	21187379

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.