dbPTM

TID_DROME - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	TID_DROME
UniProt AC	Q27237
Protein Name	Protein tumorous imaginal discs, mitochondrial
Gene Name	l(2)tid
Organism	Drosophila melanogaster (Fruit fly).
Sequence Length	520
Subcellular Localization	Mitochondrion outer membrane.
Protein Description	May act as a tumor suppressor in larval imaginal disks..
Protein Sequence	MMISCKKLFVFRQLPAVRRCLAAAAFSTPRATSYRILSSAGSGSTRADAPQVRRLHTTRDLLAKDYYATLGVAKNANGKDIKKAYYQLAKKYHPDTNKEDPDAGRKFQEVSEAYEVLSDEQKRREYDTYGQTAENIGRQGGGFPGGGAGGFGPEGFSQSWQFRSSIDPEELFRKIFGEGNFRTNSFDDFADSKFGFGQAQEMVMDLTFAQAARGVNKDVNVNVVDQCPKCAGTKCEPGTKPGRCQYCNGTGFETVSTGPFVMRSTCRYCQGTRQHIKYPCSECEGKGRTVQRRKVTVPVPAGIENGQTVRMQVGSKELFVTFRVERSDYFRREGADVHTDAAISLAQAVLGGTVRVQGVYEDQWINVEPGTSSHHKIMLRGKGLKRVNAHGHGDHYVHVKITVPSAKKLDKKRLALIEAYAELEEDTPGQIHGIANRKDGSKQATAGASEEPGAGAAAKASAAAAGSGASKPGPGAEESEGKDQWTDNKKTKAKEGGGSGSGQGDGGGGGFISKIKSMFN

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
90	Acetylation	KAYYQLAKKYHPDTN HHHHHHHHHHCCCCC	63.56	21791702
183	Phosphorylation	FGEGNFRTNSFDDFA HCCCCCCCCCHHHHH	30.95	27794539
185	Phosphorylation	EGNFRTNSFDDFADS CCCCCCCCHHHHHHC	29.46	27794539

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of TID_DROME !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of TID_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of TID_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference	Domain-Domain Interactions
PTC_DROME	ptc	physical	12783860
HH_DROME	hh	physical	12783860

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of TID_DROME

Related Literatures of Post-Translational Modification