TAF73_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TAF73_SCHPO
• UniProt AC: O74319
• Protein Name: Transcription initiation factor TFIID subunit taf73
• Gene Name: taf73
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 642
• Subcellular Localization: Nucleus.
• Protein Description: TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase transcription. Regulates the genes involved in ubiquitin-dependent proteolysis during the progression of M-phase of mitosis..
• Protein Sequence: MAQSSYSSGNSTSDLNKIVLDYLFKKGYSRTEAMLRLEISSVGAIPEEQQDWHIGASETYVQVYILLRDWIDGTLDLYKPKLQKVLYPIFVHSYLDLLQKNDPEMAIYFFESFRIEHEVLHGYDIRALAQLKIASDVEEIEIAQLYRKNKYRINFTRSTFDLLVQFLFENEVNGSGIIIRLLNQYIDIKITMPQVEGKEDPNVQAVYEMDEAKNEQTIISEQEGIPGHSEQLLDYNKQSIQLGLRPLSEEVVTTLKNLLEVKDKDVEGRNEALNKILHPAKNLVELLTEKENLINESTLESPSDPPLPPTKMKDIDYFVSLLESEQNSLILGKNATDPSVFMYTMHNTLSAVNCAAFSDDASMFALGCADSSIHLYSSTNNGPQPLVGSQNEPLQKSSLIGHTRPVFGVSISPQKEFILSCSEDGFTRLWSKDTKSTIVKYAGHNAPIWDVQFSPFGYYFATASHDQTARLWDVEHAAPLRVFVGHQNDVDCVSFHPNAAYLATGSSDHTTRMWDVRTGGTVRVFNAHHSPVSALCMSADGLSLASADESGIIKVWDLRSSNQHVSFVKHSSIVYSLSFSYDNKILVSGGADTDVNFWDLTYRNNLSDGEQSPLLFNFKTKNTIIQNLSFTRRNYCLALSSS

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
521	Phosphorylation	WDVRTGGTVRVFNAH EEECCCCEEEEEECC	13.39	29996109
607	Phosphorylation	LTYRNNLSDGEQSPL CEEECCCCCCCCCCE	45.77	25720772
612	Phosphorylation	NLSDGEQSPLLFNFK CCCCCCCCCEEEEEC	17.14	25720772

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TAF73_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TAF73_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TAF73_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TAF6_SCHPO	taf6	physical	11972332
TAF7_SCHPO	ptr6	physical	11972332
TAF7_SCHPO	ptr6	physical	11279037
T111_SCHPO	taf111	physical	11972332
T111_SCHPO	taf111	physical	11279037
TBP_SCHPO	tbp1	physical	11972332
TBP_SCHPO	tbp1	physical	11279037
TAF14_SCHPO	tfg3	physical	15616156
MTO1_SCHPO	SPBC30B4.06c	genetic	22681890
SPC2_SCHPO	spc2	genetic	22681890

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.