TAF7_SCHPO - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: TAF7_SCHPO
• UniProt AC: O13701
• Protein Name: Transcription initiation factor TFIID subunit 7
• Gene Name: taf7
• Organism: Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
• Sequence Length: 393
• Subcellular Localization: Nucleus .
• Protein Description: TAFs are components of the transcription factor IID (TFIID) complex that are essential for mediating regulation of RNA polymerase transcription. Also involved in the transport of mRNA from the nucleus to the cytoplasm..
• Protein Sequence: MVKLKIRAVQPPPNDSRSSTPATGPPPPIPKIKIKTREPKGPRLTKIRLKRVREPGLGYDSEASDREEDTYIEEQIILRLPPGEDCEYVRKAIENREVGRGADIWVKFKDQRRAVVHVNGHLYAAKLVDLPCIIESNKSFDKKVIFKAADICQMLIATERIEHENSVLNTQLKQADYIYPHGLTTPMHWVRQKRFRKRVSNRTIEAVENEVDRLLAMDERAESTSNELIDQAQLARDSSIALSEDTSFDGMAGLRGTSIDRDDQSVQTDMFDGMDEDDLAGQIEQGMLELSQDTRESTAEPRAAGEESASEEEEEEEEEEEEENEADDETRENKRQNRLVREFISELESSIQKRRKDADEATNPILRNRFLADVNRMVTELELKRTQLVDNPE

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	VQPPPNDSRSSTPAT ECCCCCCCCCCCCCC	40.48	21712547
18	Phosphorylation	PPPNDSRSSTPATGP CCCCCCCCCCCCCCC	42.38	21712547
19	Phosphorylation	PPNDSRSSTPATGPP CCCCCCCCCCCCCCC	36.98	21712547
20	Phosphorylation	PNDSRSSTPATGPPP CCCCCCCCCCCCCCC	20.42	21712547
23	Phosphorylation	SRSSTPATGPPPPIP CCCCCCCCCCCCCCC	51.96	21712547
61	Phosphorylation	EPGLGYDSEASDREE CCCCCCCCCCCCCCC	26.95	29996109
64	Phosphorylation	LGYDSEASDREEDTY CCCCCCCCCCCCCCE	32.90	29996109
223	Phosphorylation	AMDERAESTSNELID HCHHHHHHHCHHHHH	35.83	25720772
238	Phosphorylation	QAQLARDSSIALSED HHHHHCCCCCCCCCC	20.35	25720772
239	Phosphorylation	AQLARDSSIALSEDT HHHHCCCCCCCCCCC	19.03	25720772
308	Phosphorylation	PRAAGEESASEEEEE CCHHCCCCCCHHHHH	32.56	28889911
310	Phosphorylation	AAGEESASEEEEEEE HHCCCCCCHHHHHHH	55.62	28889911

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of TAF7_SCHPO !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of TAF7_SCHPO !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of TAF7_SCHPO !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RNG3_SCHPO	rng3	physical	26771498
YCHC_SCHPO	SPCC645.12c	physical	26771498

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of fission yeast.";
Wilson-Grady J.T., Villen J., Gygi S.P.;
J. Proteome Res. 7:1088-1097(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-308 AND SER-310, ANDMASS SPECTROMETRY.
PubMed: 18257517