T53G5_HUMAN - dbPTM
T53G5_HUMAN - PTM Information in dbPTM
Basic Information of Protein
UniProt ID T53G5_HUMAN
UniProt AC Q9Y2B4
Protein Name TP53-target gene 5 protein
Gene Name TP53TG5
Organism Homo sapiens (Human).
Sequence Length 290
Subcellular Localization Cytoplasm . Nucleus . Cell cycle dependent intracellular localization.
Protein Description May play a significant role in p53/TP53-mediating signaling pathway..
Protein Sequence MSPSAKKRPKNSRVSKMQDEKLRDETEQPVSKVIERNRLRTVLKNLSLLKLLKSSNRRIQELHKLAKRCWHSLLSVPKILRISSGENSACNKTKQNNEEFQEIGCSEKELKSKKLESTGDPKKKEYKEWKSQVQSGMRNKEKTSLAAMPRKEKHIEPEVPRTSRDDSLNPGVQGRQPLTEGPRVIFIKPYRNRTPMGHMKQLDVADQWIWFEGLPTRIHLPAPRVMCRSSTLRWVKRRCTRFCSASLEMPMWHPYKVDVTWTRARGASRGWRSRHQLKGRNGWRNSRVYK
Overview of Protein Modification Sites with Functional and Structural Information
Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations Modification Substrate Peptides
&
Secondary Structure		 ASA (%) Reference Orthologous
Protein Cluster
31PhosphorylationDETEQPVSKVIERNR
CCCCCCHHHHHHHHH		28.0830622161
47PhosphorylationRTVLKNLSLLKLLKS
HHHHHHHHHHHHHHC		40.8424719451
75PhosphorylationRCWHSLLSVPKILRI
HHHHHHHCCCCEEEE		41.4924719451
83PhosphorylationVPKILRISSGENSAC
CCCEEEECCCCCCCC		26.3430622161
84PhosphorylationPKILRISSGENSACN
CCEEEECCCCCCCCC		47.9930622161
88PhosphorylationRISSGENSACNKTKQ
EECCCCCCCCCCCCC		29.8730622161
93PhosphorylationENSACNKTKQNNEEF
CCCCCCCCCCCCHHH		24.7030177828
106PhosphorylationEFQEIGCSEKELKSK
HHHHHCCCHHHHHHH		46.6330622161
126PhosphorylationGDPKKKEYKEWKSQV
CCCCHHHHHHHHHHH		24.08-
151UbiquitinationSLAAMPRKEKHIEPE
CHHCCCCCCCCCCCC		66.30-
153UbiquitinationAAMPRKEKHIEPEVP
HCCCCCCCCCCCCCC		53.57-
162PhosphorylationIEPEVPRTSRDDSLN
CCCCCCCCCCCCCCC		23.2630622161
163PhosphorylationEPEVPRTSRDDSLNP
CCCCCCCCCCCCCCC		34.6830622161
167PhosphorylationPRTSRDDSLNPGVQG
CCCCCCCCCCCCCCC		34.0430622161
224MethylationRIHLPAPRVMCRSST
EECCCCCCEECCHHH		30.79115918769
228MethylationPAPRVMCRSSTLRWV
CCCCEECCHHHHHHH		18.62115918773
229PhosphorylationAPRVMCRSSTLRWVK
CCCEECCHHHHHHHH		23.8130622161
230PhosphorylationPRVMCRSSTLRWVKR
CCEECCHHHHHHHHH		16.4730622161
244PhosphorylationRRCTRFCSASLEMPM
HHHHHHHCCCCCCCC		20.41-
246PhosphorylationCTRFCSASLEMPMWH
HHHHHCCCCCCCCCC		14.47-
255PhosphorylationEMPMWHPYKVDVTWT
CCCCCCCEEEEEEEC		15.68-
286PhosphorylationGRNGWRNSRVYK---
CCCCCCCCCCCC---		17.9828152594
Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)
Modified Location Modified Residue Modification Type of Upstream Proteins Gene Name of Upstream Proteins UniProt AC of Upstream Proteins Sources

Oops, there are no upstream regulatory protein records of T53G5_HUMAN !!
Functions of PTM Sites
Modified Location Modified Residue Modification Function Reference

Oops, there are no descriptions of PTM sites of T53G5_HUMAN !!
Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location Modification Variant Position
(Distance <= 10) 		Residue Change SAP Related Disease Reference

Oops, there are no SNP-PTM records of T53G5_HUMAN !!
Protein-Protein Interaction
Interacting Protein Gene Name Interaction Type PPI Reference Domain-Domain Interactions
A4_HUMANAPPphysical
21832049
FNTB_HUMANFNTBphysical
28514442
F192A_HUMANFAM192Aphysical
28514442
PSME3_HUMANPSME3physical
28514442
DCAF1_HUMANVPRBPphysical
28514442
Drug and Disease Associations
Kegg Drug
DrugBank
There are no disease associations of PTM sites.
Regulatory Network of T53G5_HUMAN

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Related Literatures of Post-Translational Modification

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