T11L2_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: T11L2_HUMAN
• UniProt AC: Q8N4U5
• Protein Name: T-complex protein 11-like protein 2
• Gene Name: TCP11L2
• Organism: Homo sapiens (Human).
• Sequence Length: 519
• Protein Sequence: MPFNGEKQCVGEDQPSDSDSSRFSESMASLSDYECSRQSFASDSSSKSSSPASTSPPRVVTFDEVMATARNLSNLTLAHEIAVNENFQLKQEALPEKSLAGRVKHIVHQAFWDVLDSELNADPPEFEHAIKLFEEIREILLSFLTPGGNRLRNQICEVLDTDLIRQQAEHSAVDIQGLANYVISTMGKLCAPVRDNDIRELKATGNIVEVLRQIFHVLDLMQMDMANFTIMSLRPHLQRQLVEYERTKFQEILEETPSALDQTTEWIKESVNEELFSLSESALTPGAENTSKPSLSPTLVLNNSYLKLLQWDYQKKELPETLMTDGARLQELTEKLNQLKIIACLSLITNNMVGAITGGLPELASRLTRISAVLLEGMNKETFNLKEVLNSIGIQTCVEVNKTLMERGLPTLNAEIQANLIGQFSSIEEEDNPIWSLIDKRIKLYMRRLLCLPSPQKCMPPMPGGLAVIQQELEALGSQYANIVNLNKQVYGPFYANILRKLLFNEEAMGKVDASPPTN

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
16	Phosphorylation	CVGEDQPSDSDSSRF CCCCCCCCCCCCHHH	44.08	-
18	Phosphorylation	GEDQPSDSDSSRFSE CCCCCCCCCCHHHHH	43.67	22210691
20	Phosphorylation	DQPSDSDSSRFSESM CCCCCCCCHHHHHHH	27.62	22210691
21	Phosphorylation	QPSDSDSSRFSESMA CCCCCCCHHHHHHHH	42.19	22210691
24	Phosphorylation	DSDSSRFSESMASLS CCCCHHHHHHHHHCC	27.87	30576142
26	Phosphorylation	DSSRFSESMASLSDY CCHHHHHHHHHCCHH	20.60	30576142
29	Phosphorylation	RFSESMASLSDYECS HHHHHHHHCCHHHHH	21.55	30576142
31	Phosphorylation	SESMASLSDYECSRQ HHHHHHCCHHHHHHH	35.33	27642862
33	Phosphorylation	SMASLSDYECSRQSF HHHHCCHHHHHHHHH	18.56	27642862
36	Phosphorylation	SLSDYECSRQSFASD HCCHHHHHHHHHCCC	22.78	29978859
46	Phosphorylation	SFASDSSSKSSSPAS HHCCCCCCCCCCCCC	40.27	-
48	Phosphorylation	ASDSSSKSSSPASTS CCCCCCCCCCCCCCC	37.69	22199227
49	Phosphorylation	SDSSSKSSSPASTSP CCCCCCCCCCCCCCC	44.04	22199227
50	Phosphorylation	DSSSKSSSPASTSPP CCCCCCCCCCCCCCC	31.41	30576142
53	Phosphorylation	SKSSSPASTSPPRVV CCCCCCCCCCCCEEE	32.57	22199227
54	Phosphorylation	KSSSPASTSPPRVVT CCCCCCCCCCCEEEE	47.56	22199227
55	Phosphorylation	SSSPASTSPPRVVTF CCCCCCCCCCEEEEH	30.34	30576142
61	Phosphorylation	TSPPRVVTFDEVMAT CCCCEEEEHHHHHHH	23.63	30576142
68	Phosphorylation	TFDEVMATARNLSNL EHHHHHHHHHHHHHC	14.19	23090842
73	Phosphorylation	MATARNLSNLTLAHE HHHHHHHHHCHHHHH	33.08	24275569
97	Ubiquitination	KQEALPEKSLAGRVK CHHHCCCCCHHHHHH	49.16	-
244	Phosphorylation	LQRQLVEYERTKFQE HHHHHHHHHHHHHHH	11.84	22817900
305	Phosphorylation	TLVLNNSYLKLLQWD EEEECHHHHHHHHHH	15.24	-
313	Phosphorylation	LKLLQWDYQKKELPE HHHHHHHHCCCCCCH	21.19	-
321	Phosphorylation	QKKELPETLMTDGAR CCCCCCHHHCCCCHH	21.64	28674151
454	Phosphorylation	RRLLCLPSPQKCMPP HHHHCCCCCHHCCCC	27.32	29116813

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of T11L2_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of T11L2_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of T11L2_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
ACTA_HUMAN	ACTA2	physical	28514442

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.