SZRD1_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SZRD1_HUMAN
• UniProt AC: Q7Z422
• Protein Name: SUZ domain-containing protein 1
• Gene Name: SZRD1
• Organism: Homo sapiens (Human).
• Sequence Length: 152
• Protein Sequence: MEDEEVAESWEEAADSGEIDRRLEKKLKITQKESRKSKSPPKVPIVIQDDSLPAGPPPQIRILKRPTSNGVVSSPNSTSRPTLPVKSLAQREAEYAEARKRILGSASPEEEQEKPILDRPTRISQPEDSRQPNNVIRQPLGPDGSQGFKQRR

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
1	Acetylation	-------MEDEEVAE -------CCHHHHHH		19413330
9	Phosphorylation	EDEEVAESWEEAADS CHHHHHHHHHHHHHH		28348404
13 (in isoform 4)	Phosphorylation	-		-
17 (in isoform 2)	Phosphorylation	-		29743597
18 (in isoform 4)	Phosphorylation	-		29116813
19 (in isoform 2)	Phosphorylation	-		29743597
19 (in isoform 3)	Phosphorylation	-		22496350
20 (in isoform 4)	Phosphorylation	-		29116813
21 (in isoform 3)	Phosphorylation	-		22496350
34	Phosphorylation	LKITQKESRKSKSPP HCCCHHHHHCCCCCC		24719451
37	Phosphorylation	TQKESRKSKSPPKVP CHHHHHCCCCCCCCC		23927012
38 (in isoform 5)	Phosphorylation	-		25849741
39	Phosphorylation	KESRKSKSPPKVPIV HHHHCCCCCCCCCEE		29255136
51	Phosphorylation	PIVIQDDSLPAGPPP CEEECCCCCCCCCCC		22167270
67	Phosphorylation	IRILKRPTSNGVVSS EEEEECCCCCCCCCC		30266825
68	Phosphorylation	RILKRPTSNGVVSSP EEEECCCCCCCCCCC		30266825
73	Phosphorylation	PTSNGVVSSPNSTSR CCCCCCCCCCCCCCC		25159151
73	O-linked_Glycosylation	PTSNGVVSSPNSTSR CCCCCCCCCCCCCCC		31373491
74	Phosphorylation	TSNGVVSSPNSTSRP CCCCCCCCCCCCCCC		25159151
77	Phosphorylation	GVVSSPNSTSRPTLP CCCCCCCCCCCCCCC		25159151
78	Phosphorylation	VVSSPNSTSRPTLPV CCCCCCCCCCCCCCH		21712546
79	Phosphorylation	VSSPNSTSRPTLPVK CCCCCCCCCCCCCHH		21712546
82	Phosphorylation	PNSTSRPTLPVKSLA CCCCCCCCCCHHHHH		22199227
95	Phosphorylation	LAQREAEYAEARKRI HHHHHHHHHHHHHHH		28796482
104	Phosphorylation	EARKRILGSASPEEE HHHHHHHCCCCCHHH		32142685
105	Phosphorylation	ARKRILGSASPEEEQ HHHHHHCCCCCHHHH		29255136
106	Phosphorylation	RKRILGSASPEEEQE HHHHHCCCCCHHHHC		33259812
107	O-linked_Glycosylation	KRILGSASPEEEQEK HHHHCCCCCHHHHCC		OGP
107	Phosphorylation	KRILGSASPEEEQEK HHHHCCCCCHHHHCC		29255136
113	Ubiquitination	ASPEEEQEKPILDRP CCCHHHHCCCCCCCC		29967540
114	Ubiquitination	SPEEEQEKPILDRPT CCHHHHCCCCCCCCC		29967540
121	Phosphorylation	KPILDRPTRISQPED CCCCCCCCCCCCCCC		25159151
121	O-linked_Glycosylation	KPILDRPTRISQPED CCCCCCCCCCCCCCC		OGP
124	Phosphorylation	LDRPTRISQPEDSRQ CCCCCCCCCCCCCCC		21815630
129	Phosphorylation	RISQPEDSRQPNNVI CCCCCCCCCCCCCCC		21712546
148	Ubiquitination	GPDGSQGFKQRR--- CCCCCCCCCCCC---		24816145
149	Ubiquitination	PDGSQGFKQRR---- CCCCCCCCCCC----		24816145
149	Methylation	PDGSQGFKQRR---- CCCCCCCCCCC----		115980257

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SZRD1_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SZRD1_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SZRD1_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
MTMR2_HUMAN	MTMR2	physical	22863883
5NTC_HUMAN	NT5C2	physical	22863883
SRP14_HUMAN	SRP14	physical	22863883
SRP09_HUMAN	SRP9	physical	22863883
ZPR1_HUMAN	ZPR1	physical	22863883

Drug and Disease Associations

• Kegg Disease
• There are no disease associations of PTM sites.
• OMIM Disease
• There are no disease associations of PTM sites.
• Kegg Drug
• There are no disease associations of PTM sites.
• DrugBank
• There are no disease associations of PTM sites.