| UniProt ID | SYWM_YEAST | |
|---|---|---|
| UniProt AC | P04803 | |
| Protein Name | Tryptophan--tRNA ligase, mitochondrial | |
| Gene Name | MSW1 | |
| Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast). | |
| Sequence Length | 379 | |
| Subcellular Localization | Mitochondrion matrix . | |
| Protein Description | ||
| Protein Sequence | MSNKQAVLKLISKRWISTVQRADFKLNSEALHSNATVFSMIQPTGCFHLGNYLGATRVWTDLCELKQPGQELIFGVADLHAITVPKPDGEMFRKFRHEAVASILAVGVDPEKASVIYQSAIPQHSELHWLLSTLASMGLLNRMTQWKSKSNIKQSTNGDYLVNDSDVGKVRLGLFSYPVLQAADILLYKSTHVPVGDDQSQHLELTRHLAEKFNKMYKKNFFPKPVTMLAQTKKVLSLSTPEKKMSKSDPNHDSVIFLNDEPKAIQKKIRKALTDSISDRFYYDPVERPGVSNLINIVSGIQRKSIEDVVEDVSRFNNYRDFKDYVSEVIIEELKGPRTEFEKYINEPTYLHSVVESGMRKAREKAAKNLADIHKIMGF | |
| Overview of Protein Modification Sites with Functional and Structural Information | ||
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* ASA = Accessible Surface Area
| Locations | Modification | Substrate Peptides & Secondary Structure |
ASA (%) | Reference | Orthologous Protein Cluster |
|---|---|---|---|---|---|
| 169 | Acetylation | VNDSDVGKVRLGLFS ECHHCCCCEEECCCC | 24.83 | 24489116 | |
| 212 | Acetylation | LTRHLAEKFNKMYKK HHHHHHHHHHHHHHC | 48.94 | 24489116 | |
| 248 | Phosphorylation | PEKKMSKSDPNHDSV CCHHCCCCCCCCCCE | 51.50 | 27017623 | |
| 263 | Acetylation | IFLNDEPKAIQKKIR EEECCCHHHHHHHHH | 56.95 | 24489116 | |
| 282 | Phosphorylation | DSISDRFYYDPVERP HHCHHCCCCCCCCCC | 14.09 | 29688323 | |
| 283 | Phosphorylation | SISDRFYYDPVERPG HCHHCCCCCCCCCCC | 15.85 | 29688323 | |
| 292 | Phosphorylation | PVERPGVSNLINIVS CCCCCCHHHHHHHHH | 31.65 | 29688323 | |
| 299 | Phosphorylation | SNLINIVSGIQRKSI HHHHHHHHCCCCCCH | 26.78 | 29688323 | |
| 335 | Acetylation | EVIIEELKGPRTEFE HHHHHHHCCCCCHHH | 70.87 | 24489116 | |
| 353 | Phosphorylation | NEPTYLHSVVESGMR CCCHHHHHHHHHHHH | 25.84 | 27017623 | |
| 357 | Phosphorylation | YLHSVVESGMRKARE HHHHHHHHHHHHHHH | 26.69 | 27017623 |
| Modified Location | Modified Residue | Modification | Type of Upstream Proteins | Gene Name of Upstream Proteins | UniProt AC of Upstream Proteins | Sources |
|---|---|---|---|---|---|---|
Oops, there are no upstream regulatory protein records of SYWM_YEAST !! | ||||||
| Modified Location | Modified Residue | Modification | Function | Reference | ||
|---|---|---|---|---|---|---|
Oops, there are no descriptions of PTM sites of SYWM_YEAST !! | ||||||
* Distance = the distance between SAP position and PTM sites.
| Modified Location | Modification | Variant Position (Distance <= 10) |
Residue Change | SAP | Related Disease | Reference |
|---|---|---|---|---|---|---|
Oops, there are no SNP-PTM records of SYWM_YEAST !! | ||||||
| Interacting Protein | Gene Name | Interaction Type | PPI Reference | Domain-Domain Interactions |
|---|---|---|---|---|
| SIR2_YEAST | SIR2 | genetic | 21902802 | |
| GEM1_YEAST | GEM1 | genetic | 27708008 | |
| ACE2_YEAST | ACE2 | genetic | 27708008 |
| Kegg Drug | ||||||
|---|---|---|---|---|---|---|
| DrugBank | ||||||
| There are no disease associations of PTM sites. | ||||||
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