STX3_RAT - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: STX3_RAT
• UniProt AC: Q08849
• Protein Name: Syntaxin-3
• Gene Name: Stx3
• Organism: Rattus norvegicus (Rat).
• Sequence Length: 289
• Subcellular Localization: Membrane ; Single-pass type IV membrane protein .
• Protein Description: Potentially involved in docking of synaptic vesicles at presynaptic active zones..
• Protein Sequence: MKDRLEQLKAKQLTQDDDTDEVEIAIDNTAFMDEFFSEIEETRLNIDKISEHVEEAKKLYSIILSAPIPEPKTKDDLEQLTTEIKKRANNVRNKLKSMEKHIEEDEVRSSADLRIRKSQHSVLSRKFVEVMTKYNEAQVDFRERSKGRIQRQLEITGKKTTDEELEEMLESGNPAIFTSGIIDSQISKQALSEIEGRHKDIVRLESSIKELHDMFMDIAMLVENQGEMLDNIELNVMHTVDHVEKARDETKRAMKYQGQARKKLIIIIVIVVVLLGILALIIGLSVGLK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
14	Phosphorylation	QLKAKQLTQDDDTDE HHHHHHCCCCCCCCC	27.71	-
85	Acetylation	EQLTTEIKKRANNVR HHHHHHHHHHHHHHH	29.94	22902405
100	Acetylation	NKLKSMEKHIEEDEV HHHHHHHHHHCHHHH	41.04	22902405

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of STX3_RAT !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of STX3_RAT !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of STX3_RAT !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
STXB1_RAT	Stxbp1	physical	8108429
SNP25_MOUSE	Snap25	physical	7768895
STXB1_RAT	Stxbp1	physical	7768895
STXB2_RAT	Stxbp2	physical	7768895
STXB1_RAT	Stxbp1	physical	8996080

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.