SRYC_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SRYC_DROME
• UniProt AC: P15619
• Protein Name: Serendipity locus protein H-1
• Gene Name: wdn
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 869
• Subcellular Localization: Nucleus .
• Protein Description: May belong to a complex set of multifingered proteins which play an important role in gene activation or regulation at early embryonic stages through a maximal accumulation of their transcripts (or protein product) in the mature oocyte..
• Protein Sequence: MEGGKGEGKRMKEEAPSKKLPPKIYGGDAGTPTKAAHDEILSSLLRINNFDSISSIKDESLDIDLSACVTISSASLVNGNSLSSTDFWRVLDESAQNNTELNLSSDVCRDDLAATSSSTVPSTLTSDNHSSSEFSVTFLRPEPPNAFTNSPFKKTSSSGTSTPVKLSPEQLHQQHQLQMPQSQLLQRKPKLPAATAVRLKVFKEEPPEEKHPPEQVVTKVEVCESELLPPSFTIFQQAKSAESVADAASMPPPAASETKPLEVDPAPLHKCLDCNGLLLETPDEVAKHEAAAHRLRLTYRCSECQREFELLAGLKKHLKTHRTEGRKDTWKKCPDCGKCLKLGSMWMHRKIHSDNKKYQCDICGQKFVQKINLTHHARIHSSEKPYECPECQKRFQERSHLQRHQKYHAQTRSYRCEKCGKMYKTERCLKVHNLVHLEQRPFACTVCDKSFISNSKLKQHSNIHTGMRPFKCNYCPRDFTNFPNWLKHTRRRHKVDHKTGEHLENIPSYCSKKSTTNKAQKAAAAAAAAAAASSAVNPNELSASSELKAKANLTSTAAPAPAKQARKKKQPQQATLAALGITLPAGTALQQVHPVPLAQQHQQELTTVLVPLAPPAPKQTKAKRERKQLAPKQLQQKPQLLQQGQPQQSSLEPIPAVPQIKKEPVQTQGPFLDLHGLSLTSAEELIMEQALEMEECGLYDAPNANTEMGTSDNAISDSAAALHFQIKNELPDELLPDDDFLPCKPSDRLPCPSLESSPFSSPASMELTAVSCASSVAISTNALPVRSGNYYLPAFTLNAHGKLSSTGNGVQSVTTSLAQTPSVSMVNVPLLVRSNQMLPSVDTLLFTNQTGGSRFFAGKSATAATPHLT

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
5	Acetylation	---MEGGKGEGKRMK ---CCCCCCCCCCCC	65.72	21791702
9	Acetylation	EGGKGEGKRMKEEAP CCCCCCCCCCCCCCC	45.04	21791702
52	Phosphorylation	LRINNFDSISSIKDE HHHCCCCCCCCCCCC	21.89	19429919
54	Phosphorylation	INNFDSISSIKDESL HCCCCCCCCCCCCCC	29.93	19429919
55	Phosphorylation	NNFDSISSIKDESLD CCCCCCCCCCCCCCC	31.80	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SRYC_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SRYC_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SRYC_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
TULP_DROME	ktub	physical	14605208
TF2AA_DROME	TfIIA-L	physical	14605208
TIM10_DROME	Tim10	physical	25242320

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.