SIRPD_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: SIRPD_HUMAN
• UniProt AC: Q9H106
• Protein Name: Signal-regulatory protein delta
• Gene Name: SIRPD
• Organism: Homo sapiens (Human).
• Sequence Length: 197
• Subcellular Localization: Secreted .
• Protein Sequence: MPIPASPLHPPLPSLLLYLLLELAGVTHVFHVQQTEMSQTVSTGESIILSCSVPNTLPNGPVLWFKGTGPNRKLIYNFKQGNFPRVKEIGDTTKPGNTDFSTRIREISLADAGTYYCVKFIKGRAIKEYQSGRGTQVFVTEQNPRPPKNRPAGRAGSRAHHDAHTCLSALPERNSTNYFVQPCCCLRLLGLTGLLSK

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
108	Phosphorylation	STRIREISLADAGTY HHHEEEEEHHHCCCE	16.86	-
135	Phosphorylation	EYQSGRGTQVFVTEQ EECCCCCEEEEEECC	21.87	-
174	N-linked_Glycosylation	LSALPERNSTNYFVQ HHHCCCCCCCCCCHH	52.07	UniProtKB CARBOHYD
196	Phosphorylation	LGLTGLLSK------ HHHHHHHCC------	41.17	24719451

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of SIRPD_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of SIRPD_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of SIRPD_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
EPDR1_HUMAN	EPDR1	physical	28514442
DIRA2_HUMAN	DIRAS2	physical	28514442
HIKES_HUMAN	C11orf73	physical	28514442
NT5C_HUMAN	NT5C	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.