S14L3_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: S14L3_HUMAN
• UniProt AC: Q9UDX4
• Protein Name: SEC14-like protein 3
• Gene Name: SEC14L3
• Organism: Homo sapiens (Human).
• Sequence Length: 400
• Protein Description: Probable hydrophobic ligand-binding protein; may play a role in the transport of hydrophobic ligands like tocopherol, squalene and phospholipids..
• Protein Sequence: MSGRVGDLSPKQAETLAKFRENVQDVLPALPNPDDYFLLRWLRARNFDLQKSEALLRKYMEFRKTMDIDHILDWQPPEVIQKYMPGGLCGYDRDGCPVWYDIIGPLDPKGLLFSVTKQDLLKTKMRDCERILHECDLQTERLGKKIETIVMIFDCEGLGLKHFWKPLVEVYQEFFGLLEENYPETLKFMLIVKATKLFPVGYNLMKPFLSEDTRRKIIVLGNNWKEGLLKLISPEELPAQFGGTLTDPDGNPKCLTKINYGGEIPKSMYVRDQVKTQYEHSVQINRGSSHQVEYEILFPGCVLRWQFSSDGADIGFGVFLKTKMGERQRAGEMTDVLPSQRYNAHMVPEDGNLTCSEAGVYVLRFDNTYSFVHAKKVSFTVEVLLPDEGMQKYDKELTPV

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Phosphorylation	SGRVGDLSPKQAETL CCCCCCCCHHHHHHH	34.49	24719451
36	Phosphorylation	ALPNPDDYFLLRWLR CCCCHHHHHHHHHHH	11.96	24275569
83	Phosphorylation	PPEVIQKYMPGGLCG CHHHHHHHCCCCCCC	7.68	-
91	Phosphorylation	MPGGLCGYDRDGCPV CCCCCCCCCCCCCCE	13.55	-
202	Phosphorylation	TKLFPVGYNLMKPFL HCCCCCCCCCCCCCC	12.83	-
256	Phosphorylation	DGNPKCLTKINYGGE CCCCCCCEECCCCCC	39.07	22210691
267	Phosphorylation	YGGEIPKSMYVRDQV CCCCCCHHHEECCHH	15.25	22210691
288	Phosphorylation	SVQINRGSSHQVEYE EEEECCCCCCEEEEE	22.78	27251275
289	Phosphorylation	VQINRGSSHQVEYEI EEECCCCCCEEEEEE	22.29	27251275
294	Phosphorylation	GSSHQVEYEILFPGC CCCCEEEEEEECCCC	14.93	-
339	Phosphorylation	EMTDVLPSQRYNAHM CCCCCCCHHCCCCEE	24.11	24670416

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of S14L3_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of S14L3_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of S14L3_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
S14L4_HUMAN	SEC14L4	physical	28514442
S14L2_HUMAN	SEC14L2	physical	28514442

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.