RX21_DROME - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RX21_DROME
• UniProt AC: Q24491
• Protein Name: RNA-binding protein Rsf1
• Gene Name: Rsf1
• Organism: Drosophila melanogaster (Fruit fly).
• Sequence Length: 197
• Subcellular Localization: Nucleus.
• Protein Description: May control important aspects of development..
• Protein Sequence: MGDQRGTRVYVGNLTDKVKKDDLEGEFTKYGKLNSVWIAFNPPGFAFVEFEHRDDAEKACDILNGSELLGSQLRVEISKGRPRQGRRGGPMDRGGRRGDFGRHSITSGGSGGGGFRQRGSSGSSSRHTERGYSSGRSGASSYNGREGGGSGFNRREVYGGGRDSSRYSSGSSASYGRTGGQSAGRFRSRSPVGNHRF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
104	Phosphorylation	RGDFGRHSITSGGSG CCCCCCCCCCCCCCC	26.63	22817900
106	Phosphorylation	DFGRHSITSGGSGGG CCCCCCCCCCCCCCC	25.08	18327897
168	Phosphorylation	GRDSSRYSSGSSASY CCCCCCCCCCCCCCC	27.41	22817900
171	Phosphorylation	SSRYSSGSSASYGRT CCCCCCCCCCCCCCC	25.36	22817900
174	Phosphorylation	YSSGSSASYGRTGGQ CCCCCCCCCCCCCCC	30.02	22817900
188	Phosphorylation	QSAGRFRSRSPVGNH CCCCCCCCCCCCCCC	34.10	19429919
190	Phosphorylation	AGRFRSRSPVGNHRF CCCCCCCCCCCCCCC	25.78	19429919

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RX21_DROME !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RX21_DROME !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RX21_DROME !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
SRR55_DROME	B52	genetic	10090730
ISWI_DROME	Iswi	physical	26549447

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.

Related Literatures of Post-Translational Modification

Phosphorylation

"Phosphoproteome analysis of Drosophila melanogaster embryos.";
Zhai B., Villen J., Beausoleil S.A., Mintseris J., Gygi S.P.;
J. Proteome Res. 7:1675-1682(2008).
Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT THR-106; SER-168; SER-171;SER-174; SER-188 AND SER-190, AND MASS SPECTROMETRY.
PubMed: 18327897