dbPTM

RTNLA_ARATH - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RTNLA_ARATH
UniProt AC	Q9SUR3
Protein Name	Reticulon-like protein B1
Gene Name	RTNLB1
Organism	Arabidopsis thaliana (Mouse-ear cress).
Sequence Length	275
Subcellular Localization	Endoplasmic reticulum membrane Multi-pass membrane protein . Cell membrane Multi-pass membrane protein .
Protein Description	Plays a role in the Agrobacterium-mediated plant transformation via its interaction with VirB2, the major component of the T-pilus..
Protein Sequence	MAEEHKHDESVIAPEPAVEVVERESLMDKISEKIHHGGDSSSSSSSSDDEDEKKKTKKPSSPSSSMKSKVYRLFGREQPVHKVLGGGKPADIFMWKNKKMSGGVLGGATAAWVVFELMEYHLLTLLCHVMIVVLAVLFLWSNATMFINKSPPKIPEVHIPEEPILQLASGLRIEINRGFSSLREIASGRDLKKFLIAIAGLWVLSILGGCFNFLTLAYIALVLLFTVPLAYDKYEDKVDPLGEKAMIELKKQYAVLDEKVLSKIPLGPLKNKKKD

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
2	Acetylation	------MAEEHKHDE ------CCCCCCCCC	30.77	-
6	Acetylation	--MAEEHKHDESVIA --CCCCCCCCCCCCC	56.91	21311031
10	Phosphorylation	EEHKHDESVIAPEPA CCCCCCCCCCCCCCC	25.53	25368622
31	Phosphorylation	ESLMDKISEKIHHGG HHHHHHHHHHHCCCC	38.28	30291188
40	Phosphorylation	KIHHGGDSSSSSSSS HHCCCCCCCCCCCCC	35.08	19376835
41	Phosphorylation	IHHGGDSSSSSSSSD HCCCCCCCCCCCCCC	38.69	19376835
42	Phosphorylation	HHGGDSSSSSSSSDD CCCCCCCCCCCCCCC	37.89	19376835
43	Phosphorylation	HGGDSSSSSSSSDDE CCCCCCCCCCCCCCH	35.87	19376835
44	Phosphorylation	GGDSSSSSSSSDDED CCCCCCCCCCCCCHH	35.87	27531888
45	Phosphorylation	GDSSSSSSSSDDEDE CCCCCCCCCCCCHHH	35.49	19376835
46	Phosphorylation	DSSSSSSSSDDEDEK CCCCCCCCCCCHHHH	39.47	27531888
47	Phosphorylation	SSSSSSSSDDEDEKK CCCCCCCCCCHHHHH	51.53	19376835
56	Phosphorylation	DEDEKKKTKKPSSPS CHHHHHHCCCCCCCC	53.86	19376835
60	Phosphorylation	KKKTKKPSSPSSSMK HHHCCCCCCCCHHHH	64.85	23776212
61	Phosphorylation	KKTKKPSSPSSSMKS HHCCCCCCCCHHHHH	37.01	19880383
63	Phosphorylation	TKKPSSPSSSMKSKV CCCCCCCCHHHHHHH	36.67	23776212
64	Phosphorylation	KKPSSPSSSMKSKVY CCCCCCCHHHHHHHH	37.52	23776212
65	Phosphorylation	KPSSPSSSMKSKVYR CCCCCCHHHHHHHHH	34.27	23776212

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RTNLA_ARATH !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RTNLA_ARATH !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RTNLA_ARATH !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
RTNLB_ARATH	BTI2	physical	15494553
RTNLD_ARATH	BTI3	physical	15494553
RAE1A_ARATH	RAB8	physical	15494553
RTNLA_ARATH	BTI1	physical	15494553
RTNLA_ARATH	BTI1	physical	20424177
RTNLC_ARATH	RTNLB3	physical	20424177
RTNLD_ARATH	BTI3	physical	20424177
FLS2_ARATH	FLS2	physical	21949153

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RTNLA_ARATH

Related Literatures of Post-Translational Modification

Phosphorylation
Reference	PubMed
"Large-scale Arabidopsis phosphoproteome profiling reveals novelchloroplast kinase substrates and phosphorylation networks."; Reiland S., Messerli G., Baerenfaller K., Gerrits B., Endler A.,Grossmann J., Gruissem W., Baginsky S.; Plant Physiol. 150:889-903(2009). Cited for: PHOSPHORYLATION [LARGE SCALE ANALYSIS] AT SER-61, AND MASSSPECTROMETRY.	19376835 [Abstract]