RTL8C_HUMAN - PTM Information in dbPTM

Basic Information of Protein

• UniProt ID: RTL8C_HUMAN
• UniProt AC: A6ZKI3
• Protein Name: Retrotransposon Gag-like protein 8B {ECO:0000312|HGNC:HGNC:2569}
• Gene Name: RTL8C {ECO:0000312|HGNC:HGNC:2569}
• Organism: Homo sapiens (Human).
• Sequence Length: 113
• Protein Sequence: MDGRVQLIKALLALPIRPATRRWRNPIPFPETFDGDTDRLPEFIVQTGSYMFVDENTFSSDALKVTFLITRLTGPALQWVIPYIKKESPLLNDYRGFLAEMKRVFGWEEDEDF

Overview of Protein Modification Sites with Functional and Structural Information

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference
9	Ubiquitination	DGRVQLIKALLALPI CHHHHHHHHHHHCCC		23000965
64	Sumoylation	TFSSDALKVTFLITR CCCCHHHHHHEEHHH		-
85	Ubiquitination	QWVIPYIKKESPLLN HHHHHHHCCCCCCCC		23000965
85	Sumoylation	QWVIPYIKKESPLLN HHHHHHHCCCCCCCC		-
86	Ubiquitination	WVIPYIKKESPLLND HHHHHHCCCCCCCCC		23000965
86	Sumoylation	WVIPYIKKESPLLND HHHHHHCCCCCCCCC		-
102	Ubiquitination	RGFLAEMKRVFGWEE HHHHHHHHHHHCCCC		21963094

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Oops, there are no upstream regulatory protein records of RTL8C_HUMAN !!

Functions of PTM Sites

Oops, there are no descriptions of PTM sites of RTL8C_HUMAN !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Oops, there are no SNP-PTM records of RTL8C_HUMAN !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
A4_HUMAN	APP	physical	21832049
PEG10_HUMAN	PEG10	physical	25416956
UBQL1_HUMAN	UBQLN1	physical	25416956

Drug and Disease Associations

• Kegg Drug
• DrugBank
• There are no disease associations of PTM sites.