dbPTM

RNF37_MOUSE - PTM Information in dbPTM

Basic Information of Protein

Overview of Protein Modification Sites with Functional and Structural Information
UniProt ID	RNF37_MOUSE
UniProt AC	Q925F4
Protein Name	RING finger protein 37 {ECO:0000305}
Gene Name	Ubox5
Organism	Mus musculus (Mouse).
Sequence Length	539
Subcellular Localization	Nucleus . Enriched in nuclear bodies.
Protein Description	May have a ubiquitin-protein ligase activity acting as an E3 ubiquitin-protein ligase or as a ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates..
Protein Sequence	MVVNLCLPQFRPRIHCNKVSADGYEVENLISEDLIKRSHGFRTEYFIRPPIYVTVSFPFNVEICRVNIDLTTGGYQNVSGLELYTSALSSRVSQDAQDCWTTGPVETSVPDKEAFTLVGKVLLKNQNHVVFSHRGFKARPPFSPMEVTLLSPAVVAQELWNKGALSLSHVAHLKIGITHVTGSGISCIKRLEVWGQPARTCSQEVINSVLLIASESLPQDLDLHAPALPMESDCDPGGQSESQHSPCTLQDMSEVESDVPEEFLDPITLEIMPCPMLLPSGKVIDQSTLEKCNLSEAAWGRVPSDPFTGLAFTPQSQPLPHPSLKARIDRFLLQHSISGCRLLGRAQTPSAMTPSVITLPSRKRKTEQAEHSSHYSLGMSASSSATSPLFSPTTSEPTAKKMKATSELGLTDMDCSAGPVSHEQKLAQSLEIALTSTLGSMPSFTARLTKGQLQLGTRGSSACRRPASSSEHPRSVSGPECASCKQAFSSYSTNEPVYQLPCGHLLCRPCLSEKQRSQPMMCTACRQPVTSQDVLRVHF

Experimental Post-Translational Modification Sites

* ASA = Accessible Surface Area

Locations	Modification	Substrate Peptides & Secondary Structure	ASA (%)	Reference	Orthologous Protein Cluster
348	Phosphorylation	RLLGRAQTPSAMTPS EECCCCCCCCCCCCC	20.44	26745281
350	Phosphorylation	LGRAQTPSAMTPSVI CCCCCCCCCCCCCEE	33.78	26745281

Upstream regulatory proteins (kinases for phosphorylation sites, E3 ubiquitin ligases of ubiquitination sites, ...)

Modified Location	Modified Residue	Modification	Type of Upstream Proteins	Gene Name of Upstream Proteins	UniProt AC of Upstream Proteins	Sources
Oops, there are no upstream regulatory protein records of RNF37_MOUSE !!

Functions of PTM Sites

Modified Location	Modified Residue	Modification	Function	Reference
Oops, there are no descriptions of PTM sites of RNF37_MOUSE !!

Disease-associated PTM Sites based on SAP

* Distance = the distance between SAP position and PTM sites.

Modified Location	Modification	Variant Position (Distance <= 10)	Residue Change	SAP	Related Disease	Reference
Oops, there are no SNP-PTM records of RNF37_MOUSE !!

Protein-Protein Interaction

Interacting Protein	Gene Name	Interaction Type	PPI Reference
UB2L3_HUMAN	UBE2L3	physical	11274149
UB2D1_HUMAN	UBE2D1	physical	11274149
TERA_MOUSE	Vcp	physical	15189447
TERA_HUMAN	VCP	physical	15189447

Drug and Disease Associations

Kegg Drug
DrugBank
There are no disease associations of PTM sites.

Regulatory Network of RNF37_MOUSE

Related Literatures of Post-Translational Modification